2020年全球爆發新型冠狀病毒病大流行。這場發展迅速的大流行，突顯了全世界各國的生物科技產業之重要性和能力。生技產業的運營管理特性，除了需尋求投資來源及擴大收入之外，成本控制同樣非常重要，以達到利潤最大化，進而增加股東的投資信心。但，對於擁有大量高技術員工的生技公司來說，這導致他們在收入減少時，仍必須保留他們的高技術員工。這會造成勞動成本的僵固性。近年來，日本國內聘用非正式員工的數量提升。此研究目的旨在探討臺灣和日本生技公司之勞動成本的僵固性，並瞭解非正式員工影響兩國生技公司之財務績效。觀察期為2003年至2021年。個案選取了SIC代碼2833-2836和8731-8734，共計定義生技公司192家及1,247個公司年觀察值。結果顯示，臺灣和日本的生技公司都存在勞動成本的抗僵固性。但顯然，當無論收入增加或減少時，臺灣生技公司的勞動成本的變動幅度皆大於日本生技公司，且在勞動成本增加幅度相同時，臺灣生技公司的財務績效增長幅度也高於日本。

The global pandemic COVID-19 was declared outbreak by World Health Organization. This rapid development pandemic has highlighted the importance and ability of the biotechnology industry in different countries (Industrial Development Bureau, Ministry of Economic Affairs, 2021). Be the leading role in the biotechnology industries, the operating management of biotech firms is obviously very important. Besides expanding revenue and seeking investing sources, cost control is equally important. As for biotech firm has lots skilled employees, that induced firms keep their manpower when revenue is decrease. This responds to the result of labor cost stickiness. Japan’s precarious employees has increased recently. The aimed of this study is to explore whether there is labor cost stickiness in the biotech companies in Japan and Taiwan and compare these two countries’ financial performance. We observed 19 years (2003-2021), 192 companies with 1,247 firm-year observations. The sample was selected by SIC codes 2833-2836 Office of Life Sciences & 8731-8734 Industrial Applications and Services, from the DataStream via Eikon. We found that there was labor costs anti-stickiness of biotech companies both in Taiwan and Japan. But obviously, Taiwan firms have larger amplitude of labor cost changed when revenues decrease. And Taiwan biotech companies has higher ROA increased then Japan when under the same increased amplitude of labor cost.

Aarto, S., & Kano, S. (2021). Platform technology management of biotechnology companies in Japan. Journal of Commercial Biotechnology, 26(0), 25-36.
Anderson, M. C., Banker, R. D., & Janakiraman, S. N. (2003). Are selling, general, and administrative costs “sticky”? Journal of Accounting Research, 41(1), 47-63.
Anghel, I., Marian, S., Cristea, M., Sichigea, M., & Noja, G. (2018). Intellectual capital and financial performance of biotech companies in the pharmaceutical industry. Amfiteatru Economic, 20(0), 631-646.
Atasel, O., Şeker, Y., & Yildirim, F. (2021). Sticky cost behavior: evidence from BRICS+T Countries. Ege Akademik Bakis (Ege Academic Review), 125-137.
Banker, R., & Mack, C. (2006). Labor market characteristics and cross-country differences in cost stickiness. SSRN Electronic Journal.
Banker, R. D., & Byzalov, D. (2014). Asymmetric cost behavior. Journal of Management Accounting Research, 26(2), 43-79.
Banker, R. D., Byzalov, D., Ciftci, M., & Mashruwala, R. (2014). The moderating effect of prior sales changes on asymmetric cost behavior. Journal of Management Accounting Research, 26(2), 221-242.
Bugeja, M., Lu, M., & Shan, Y. (2015). Cost stickiness in Australia: characteristics and determinants. Australian Accounting Review, 25(0).
Calleja, K., Steliaros, M., & Thomas, D. C. (2006). A note on cost stickiness: some international comparisons. Management Accounting Research, 17(2), 127-140.
Chen, C., Lu, H., & Sougiannis, T. (2011). The agency problem, corporate governance, and the asymmetrical behavior of selling, general, and administrative costs. Contemporary Accounting Research, 29(0), 252-282.
Cheng, W.-C. (2008). The development trends and prospects of Taiwan's biotech industry. (Master), Asia University. Available from Airiti AiritiLibrary database. (2008)
Cheung, J., Kim, H., Kim, S., & Huang, R. (2018). Is the asymmetric cost behavior affected by competition factors?*. Asia-Pacific Journal of Accounting & Economics, 25(1-2), 218-234.
Cho, D. (2017). Downward wage rigidity, corporate investment, and firm value. SSRN Electronic Journal.
Cho, D. (2022). Downward wage rigidity, corporate investment, and firm value.
Demirkan, I. and Demirkan, S. (2012). “Network Characteristics and Patenting in Biotechnology, 1990-2006”, Journal of Management, 38(6): 1892-1927.
Dierynck, B., Landsman, W. R., & Renders, A. (2012). Do managerial incentives drive cost behavior? evidence about the role of the zero earnings benchmark for labor cost behavior in private belgian firms. The Accounting Review, 87(4), 1219-1246.
Eltivia, N., Ekasari, K., Wahyuni, H., & Isrowiyah, A. (2019). How adjustment cost relate with stickiness cost? Jurnal Reviu Akuntansi dan Keuangan, 9(0), 319.
Eyo, S. J. (2011). A comparison of biotechnology industry in Japan and other developed countries. SSRN Electronic Journal.
Eyo, S. J. (2020). A Review of Japan’s Bioventures.
Farid, S. S., Baron, M., Stamatis, C., Nie, W., & Coffman, J. (2020). Benchmarking biopharmaceutical process development and manufacturing cost contributions to R&D. MAbs, 12(1), 1754999.
Finegold, D., & Frenkel, S. (2006). Managing people where people really matter: the management of human resources in biotech companies. International Journal of Human Resource Management - INT J HUM RESOUR MANAG, 17(0), 1-24.
Fujiwara, T. (2016). Potential and challenges for start-ups in Japan’s biotech industry. Global Journal of Flexible Systems Management, 17(4), 417-424.
Golden, J., Mashruwala, R., & Pevzner, M. (2020). Labor adjustment costs and asymmetric cost behavior: an extension. Management Accounting Research, 46, 100647.
Habib, A., & Huang, H. J. (2019). Cost stickiness in the New Zealand charity sector. The International Journal of Accounting, 54(3), 1950012.
Han, S., Rezaee, Z., & Tuo, L. (2020). Is cost stickiness associated with management earnings forecasts? Asian Review of Accounting, 28(2), 173-211.
Hartlieb, S. and Loy, T.R. (2022), The impact of cost stickiness on financial reporting: evidence from income smoothing. Account Finance, 62(0), 3913-3950.
He, D., Teruya, J., & Shimizu, T. (2010). Sticky selling, general, and administrative cost behavior and its changes in Japan. Global Journal of Business Research, 4.
Ibrahim, A. E. A., Ali, H., & Aboelkheir, H. (2022). Cost stickiness: a systematic literature review of 27 years of research and a future research agenda. Journal of International Accounting, Auditing and Taxation, 46(0), 100439.
Ibrahim, A. E. A., & Ezat, A. N. (2017). Sticky cost behavior: evidence from Egypt. Journal of Accounting in Emerging Economies, 7(1), 16-34.
Jakovljevic, M., Wu, W., Merrick, J., Cerda, A., Varjacic, M., & Sugahara, T. (2021). Asian innovation in pharmaceutical and medical device industry - beyond tomorrow. Journal of medical economics, 24(0), 42–50.
Jugović, J. (2021). Are costs sticky? evidence from Serbia. Facta Universitatis, Series: Economics and Organization, 7(3).
Kim, Irene & Skinner, Douglas J., (2012). Measuring securities litigation risk, Journal of Accounting and Economics, Elsevier, 53(1), 290-310.
Kong, D., Liu, S., & Shen, R. (2023). Labor cost stickiness and managerial decisions on human capital adjustment. Journal of Accounting Literature, 46(0)
Kuiate, C., & Noland, T. R. (2019). Attracting and retaining core competency: a focus on cost stickiness. Journal of Accounting & Organizational Change, 15(4), 678-700.
Li, Z., Cheng, X., Zhang, M., & Wen, X. (2020, December 01, 2020). Macroeconomic uncertainty and cost stickiness. Paper presented at the E3S Web of Conferences.
Liang, W., & Liu, T. (2021). The impact of the act for the development of biotech and new pharmaceuticals industry on firm innovation in Taiwan. [生技新藥產業發展條例對公司創新影響]. NTU Management Review, 31(2), 129-188.
Lin, M.-X., Liou, H.M. & Chou, K.T., (2020) National Energy Transition Framework toward SDG7 with Legal Reforms and Policy Bundles: The Case of Taiwan and Its Comparison with Japan. Energies, 13(0), 1387.
Lin. M. M, & Lekhawipat. W., (2023). Key influencing factors for the success of external innovation strategies in the biotechnology industry. Journal of Business & Industrial Marketing, 38(12), 2745-2759
Llanos Reynoso, L. F., Vela-Beltran-del-Rio, C., & Martínez-Berrones, J. (2021). Sticky costs and expenses are not alike: Mexican reality. Journal of Accounting, Business and Management (JABM), 28(0), 14.
Lusiana, L., & Kristianti, I. (2020). Sticky cost behavior in selling, general, and administrative costs in Indonesian manufacturing companies. Jurnal Keuangan dan Perbankan, 24(0).
Makni Fourati, Y., Chakroun Ghorbel, R., & Jarboui, A. (2020). Sticky cost behavior and its implication on accounting conservatism: a cross-country study. Journal of Financial Reporting and Accounting, 18(1), 169-197.
Martin, D., Vicente, O., Beccari, T., Kellermayer, M., Koller, M., Lal, R., Dundar, M. (2021). A brief overview of global biotechnology. Biotechnology & Biotechnological Equipment, 35(0), 354-363.
Müller-Roterberg, C., & Fujiwara, T. (2002). The commercialization of biotechnology in Japan. Drug discovery today, 7(0), 699-704.
Noreen, E. W., & Soderstrom, N. S. (1997). The accuracy of proportional cost models: evidence from hospital service departments. Review of Accounting Studies, 2(0), 89-114.
Park, T., & Jun, y. K. (2022). An exploratory study on innovation policy in eight asian countries. Journal of Science and Technology Policy Management, 13(2), 273-303.
Priantana, R., & Sayuthi, S. (2020). How does research in sticky cost develop? A Review of Major Themes. Journal of Accounting Research, Organization and Economics, 3(0), 117-126.
Rennane, S., Baker, L., & Mulcahy, A. (2021). Estimating the Cost of Industry Investment in Drug Research and Development: A Review of Methods and Results. The Journal of Health Care Organization, 58(0), 1-11
Ronny Prabowo, Reggy Hooghiemstra, & Veen-Dirks, P. V. (2018). State ownership, socio-political factors, and Labor Cost Stickiness. European Accounting Review, 27(4), 25.
Shibata, S., & Suzuki, T. (2018). The pharmaceutical market and drug development prognosis in Japan: current and future perspectives according to pharmacological classes. Journal of Generic Medicines, 14(2), 70-80.
Shirzad, A., Saei, M., & Nassirzadeh, F. (2020). A new methodology for identifying the sources of cost stickiness and investigating their effects on earnings forecast accuracy. SSRN Electronic Journal.
Shust, E., & Weiss, D. (2014). Discussion of asymmetric cost behavior—sticky costs: expenses versus cash flows. Journal of Management Accounting Research, 26(2), 81-90.
Subramaniam, C., & Watson, M. W. (2016). Additional evidence on the sticky behavior of costs Advances in Management Accounting (Vol. 26, pp. 275-305): Emerald Group Publishing Limited.
Teruyama, H., Goto, Y., & Lechevalier, S. (2018). Firm-level labor demand for and macroeconomic increases in non-regular workers in Japan. Japan and the World Economy, 48(0), 90-105.
Terziovski, M. & Morgan, J.P. (2006). Management Practices and Strategies to Accelerate the Innovation Cycle in the Biotechnology Industry. Technovation, 26(0), 545-552.
Tileal, M. Nassirzadeh F., Saei M.J., Askarany D. (2023). The Impact of Ownership Type on Labour Cost Stickiness. Journal of Risk and Financial Management. 16(5), 268.
Tuo, L., Yu, J. & Zhang, Y. (2020). How do industry peers influence individual firms’ voluntary disclosure strategies?. Rev Quant Finan Acc 54(0), 911–956.
Wahdan, M., Ahmed, A., & Saber Hamoda Alsayed, M. (2021). Does sticky cost behavior affect earnings quality? Evidence From Egypt. International Journal of Accounting and Financial Reporting, 11(0), 17.
Weiss, D. (2010). Cost Behavior and analysts' earnings forecasts. Accounting Review, 85.
Wu, T. C., Young, C.-S., Yu, C.-C., & Hsu, H.-T. (2020). Are governmental expenditures also sticky? evidence from the operating expenditures of public schools. Applied Economics, 52(16), 1763-1776.
Yang, G., Kuang, Y., & Li, B. (2020). Staying idle or investing in prevention: the short-term and long-term impact of cost stickiness on firm value. China Journal of Accounting Studies, 8(0), 1-32.
Zhang, Q. (2016). A study on the labor cost of chinese listed companies—based on the perspective of labor contract law. Modern Economy, 7(0), 164-172.
Zhong, T., Sun, F., Zhou, H., & Lee, J. Y. (2020). Business strategy, state-owned equity and cost stickiness: evidence from chinese firms. Sustainability, 12(5), 1850.