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研究生: 詹昆霖
Zhan, Kun-Lin
論文名稱: 2.45 GHz醫療熱消融探針之研究
Study on 2.45 GHz Medical Thermal Ablation Probe
指導教授: 李嘉猷
Lee, Jia-You
李祖聖
Li, Tzuu-Hseng S.
學位類別: 碩士
Master
系所名稱: 電機資訊學院 - 電機工程學系
Department of Electrical Engineering
論文出版年: 2024
畢業學年度: 112
語文別: 中文
論文頁數: 80
中文關鍵詞: 微波熱消融微波消融探針諧振頻率RLC 諧振電路空間諧振
外文關鍵詞: microwave thermal ablation, microwave ablation probe, resonant frequency, RLC resonant tank, spatial resonance
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  • 本研究旨在提出一種新的微波熱消融工具,有別於現今醫療體系常用之大面積經皮穿刺,期望以感應方式減少侵入式治療造成的不必要熱損傷,進而導致的併發症如內出血或者周邊組織燒傷。本論文建議之微波消融探針利用空間諧振產生熱能熱殺癌細胞,能以簡單微波照射方式加溫目標區域,進而達成醫療目的。本文以高頻電磁模擬軟體設計中心頻率為 2.45 GHz 的微波消融探針,藉由模擬觀察在該諧振頻率下的目標物阻抗特性,給出對應的 RLC 諧振電路模型,並且根據電、磁場形分布,選擇適當的結構設計。接著透過內部場形影響造成的導體損耗產生熱能,使熱能量可在小面積範圍內產生,推斷依著空間諧振的觀念能達成論文目標之微波消融探針用於熱治療。模擬結果顯示本研究所提方法能提供設計的自由度並具有可行性。

    The aim of this study is to propose a novel microwave thermal ablation method, distinct from the current medical practice of large-area percutaneous puncture. It is hoped that by utilizing an induction approach, unnecessary thermal damage caused by invasive treatments can be reduced, thereby minimizing complications such as internal bleeding or peripheral tissue burns. The proposed microwave ablation probe utilizes spatial resonance to generate heat energy for cancer cell ablation. It achieves medical objectives through simple microwave irradiation of the target area. In this thesis, a microwave ablation probe with a center frequency of 2.45 GHz is designed using high-frequency electromagnetic simulation software. The impedance characteristics of the target object at this resonance frequency are observed through simulation, leading to the derivation of the corresponding RLC resonance circuit model. Based on the distribution of electric and magnetic fields, appropriate structural designs are selected. Subsequently, heat energy is generated through conductor losses induced by internal field effects, allowing heat to be produced within a small area. It is inferred that the concept of spatial resonance can achieve the goal of using microwave ablation probes for thermal therapy. Simulation results demonstrate that the proposed idea in this study offers design flexibility and feasibility.

    中文摘要 I 英文摘要 II 英文延伸摘要 III 誌謝 X 目錄 XI 表目錄 XIII 圖目錄 XIV 第一章 緒論 1 1-1 研究動機與目的 1 1-2 研究背景與方法 3 1-3 論文大綱 9 第二章 相關文獻技術探討 10 2-1 生物阻抗分析技術 10 2-2 微波消融相關技術 14 2-3 電磁熱療於手術之應用 19 2-4 腫瘤阻抗分析相關技術 22 第三章 微波消融探針設計原理 24 3-1 前言 24 3-2 相關電磁理論 25 3-3 諧振理論 28 3-4 傳輸線諧振電路 33 3-5 2.45 GHz 微波消融探針設計 37 第四章 微波消融探針模擬結果 42 4-1 前言 42 4-2 2.45 GHz FR4 材料微波消融探針模擬 42 4-3 2.45 GHz Teflon 材料微波消融探針模擬 47 4-4 模擬結果與討論 53 第五章 結論與未來研究方向 56 5-1 結論 56 5-2 未來研究方向 57 參考文獻 58

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