為了降低骨科手術術後感染的風險，因而本實驗進行抗菌型骨泥的探討，選擇C化合物當抗菌劑加入具有良好生物相容性與骨誘導性的c-cpc與CSH的複合材中。
本實驗使用金黃色葡萄球菌當抗菌測試實驗的菌種，測試抗菌型鈣基骨泥的抗菌效果，並選擇C化合物添加入複合材(cement)中，探討此抗菌型骨泥的各種性質，挑選出具有適當工作時間、硬化時間及良好崩解性質之抗菌型鈣基骨泥條件來進行長期浸泡的實驗。將硬化劑Lx(Lx)添加1vol%Px(PX)後，可明顯改善抗菌型鈣基骨泥之注射崩解性。
抗菌型鈣基骨泥未浸泡Hanks’ solution前有明顯抗菌效果，且在浸泡Hanks’ solution一天或更久後觀察到大量巨大孔洞且孔隙率也隨之增加，在浸泡三天後因YZ析出強化，使骨泥強度明顯上升，且細胞存活率達70%以上，證明此抗菌型鈣基骨泥具有生物相容性，有潛質應用於骨頭修損。

In order to reduce the risk of postoperative infection in orthopedic surgery, lithium carbonate as an antibacterial agent is added into the c-cpc which has good biocompatibility and osteoinduction.
The Staphylococcus aureus strains were used to investagate the antibacterial effect of the antibacterial calcium-based cement. In addition, the structure, properties and cytotoxicity of the present cement were also investigated and evaluate its suitability for being used as a bone void filler material. Then, we explore various properties of the antibacterial calcium-based cement, and choose the appropriate properties, including the appropriate working time, setting time and without dispersion, for further long-term immersion experiments. The problem of the dispersion was improved by adding 1 volume % PX into the diammonium hydrogen phosphate (Lx) hardening solution.
Before being immersed in the Hanks’ solution, the antibacterial calcium-based cement has the obvious antibacterial property. And after being immersed in the Hanks’ solution for 1 day or longer, lots of large pores were observed and the porosity values increased. The strength of the antibacterial calcium-based cement increases due to the precipitation of YZ, the the cell viability value of present cement is greater than 70% after being immersed in the Hanks’ solution for 3 days. These experimental results showed that the antibacterial calcium-based cement has the good biocompatibility, and initial antibacterial ability, indicating that it has the potential to be applied on the bone repair damage.

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