地球本身即有自然磁場，以屏蔽太陽風所帶來的帶電粒子，使得在地球內部的生物得以生長、演化，然而隨著科技的發展，電磁場對於生物的影響與時俱增，生物不再僅僅暴露於自然磁場，而是自然磁場與人造電磁場的複雜環境下，在人造電磁場中，由其以極低頻頻段之電磁場更是與生活息息相關，也是與人類接觸最頻繁的波段，極低頻電磁場對於細胞的影響逐漸受到關注，過去文獻中，電磁場對細胞的正、反影響皆有，但以射頻影響正常細胞占多數，此外在相關論點多以電磁場影響鈣離子濃度，進而影響細胞生長。本研究利用規格化線圈及電路產生不同頻段電磁場，作用在小鼠黑色素腫瘤癌細胞B16F10上，並利用MTT檢測的方式，觀察癌細胞活性比率，並應用共振電路及其傳輸能量效率，探討鈣離子受不同頻段電磁場影響所造成的不同結果。實驗結果顯示，當給予接近鈣離子迴旋共振的頻率也就是傳遞能量最有效率之頻率7.83 Hz時，細胞活性比率是最低。

Earth has a geomagnetic field to shield the charge particles of solar winds brought, therefore the creature in earth can grow and evolve. However, with the development of technology electromagnetic fields effect on living organisms increasing with time. Life in earth is not only expose to natural magnetic, but also expose to complex electromagnetic fields and natural magnetic. In artificial electromagnetic fields, especially the extremely low frequency is intensive connecting with human normal living. The effect of extremely low frequency electromagnetic fields on cells attract more extensive attention. In the past studies, electromagnetic fields have both positive and negative effect on cells. But most of researches are concern about normal cells. Moreover, most related arguments are point out that electromagnetic fields effect on calcium concentration then changing cells proliferation. In this study, we used grid coils and electric circuit to generate different frequency electromagnetic fields effect on mice melanoma cancer cells, B16F10 and tested tumor cells viability by MTT assay. Discussing calcium ion effected by different frequency electromagnetic fields cause different results. The experiment results demonstrate that applying nearly calcium ion cyclotron resonance frequency, which is the most efficient energy transfer frequency of 7.83 Hz, shows the lowest rate of cell activity.

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