靜電紡絲(electrospinning)為製備奈米纖維的新穎技術，其操作簡易且多方適用。靜電紡絲奈米纖維因具有高比表面積(surface-to-volume ratio)而廣泛被應用。本實驗以自由基聚合法合成不同比例之共聚高分子 poly((N-isopropylacrylamide)-co-(N-hydroxymethylacrylamide)-co-(2-(1,2,3,4,5-pentaphenyl-1H-silol-1-yloxy)ethyl methacrylate)) (poly(NIPAAm-co-NMA-co-(PPS-HEMA)))，P1、P2及P3，並藉由靜電紡絲技術將其製成奈米纖維做為感測之應用，成功製備出多功能性螢光靜電紡絲奈米纖維。其中PNIPAAm為具有熱敏感性質之鏈段，其親疏水特性受溫度影響而改變。PNMA做為奈米纖維之化學交聯鏈段，經過熱交聯後得以使纖維形態在溶液中維持穩定。螢光分子方面，具有聚集誘導發光(aggregation-induced emission)性質的PPS-HEMA於親和力強的有機溶劑時發出極弱螢光，但在聚集狀態時因分子內轉動被限制而誘發螢光增強。利用場效發射式掃描電子顯微鏡(FE-SEM)觀察纖維交聯前後之形態變化，並將交聯後之纖維應用於感測。感測表現上，靜電紡絲纖維因具有較高的比表面積而比薄膜具有較佳的感測靈敏度。而且靜電紡絲纖維能多次重複感測，進而達到可再利用的目的。

Electrospinning (ES) is a simple and versatile method for manufacturing continuous nanofibers. ES nanofibers with their large surface-to-volume ratio are widely used for various applications. In this study, novel fluorescent ES nanofibers are successfully prepared from random copolymers of poly(NIPAAm-co-NMA-co-(PPS-HEMA)) through free radical polymerization and followed by electrospinning for optical applications. PNIPAAm segments with thermo-responsive properties exhibit a hydrophilic-hydrophobic change as the temperatures varied. PNMA segments with chemically cross-linking moiety stabilize the morphology of nanofibers in the solution after thermal cross-linking. PPS-HEMA segments with aggregation-induced emission (AIE) phenomenon show much weaker emission in a good organic solvent. Upon aggregate formation, the emission of these AIE dyes is induced to increase by the effect of the restricted intramolecular rotation. The morphology of nanofibers before/after cross-linking were observed by Field Emission Scanning Electron Microscopy (FE-SEM). The high surface-to-volume ratio of ES nanofibers enhanced the sensitivity compared with that of spin-coating film. Furthermore, the optical measurements of ES nanofibers were reusable for several times.

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