本研究以紮根理論法探索10位甲狀腺低功能症篩檢陽性結果新生兒的母親及8位父親於面對新生兒甲狀腺低功能症篩檢陽性結果時，與環境互動之下的經驗歷程，最後以父母親的真實經驗建立「在不確定中找尋定位點」理論。
研究者以參與觀察方式，收集父母帶新生兒到醫學中心進行複診及確診期間的反應及行為，並在確診後一個月內進行深入訪談，共得 26篇實地札記，18份訪談逐字稿，而後以持續性比較法進行資料分析與編碼，整理出此經驗歷程包含「心慌意亂：出乎意外的消息」、「既期待又怕受傷害：難熬的等待」、「臨機應變：先了解再打算」、「平心靜氣：面對診斷的心理準備」、「喜憂參半：對未來擔憂和不確定」五個範疇，發展出「在不確定中找尋定位點」作為理論的核心概念。
「在不確定中找尋定位點」理論呈現父母親在面對新生兒篩檢陽性結果時，經歷等待診斷的忐忑以及無法預測的未來之不確定過程；歷程中父母不斷在孩子罹病的可能與罹病所帶來的後果之間尋找定位點，欲找到ㄧ個安心、可以接受的定位，主要目的在於減少父母面臨診斷前的不安，增加面對診斷的信心。
研究結果可以增進健康照護者了解父母面對篩檢陽性結果時的反應。建議未來可以朝如何幫助父母在歷程中找到定位點以及建立雙向溝通的管道作進一步的研究。

The purposes of this study were (1) to explore parents’ experience about encountering the positive result of newborn screening on congenital hypothyroidism (CHT); (2) to generate knowledge about the parents’ uncertainty experience and coping process since they received positive CHT screening result till being disclosed diagnosis period.
Eighteen subjects (10 mothers and 8 Fathers) were recruited from a referral medical center in southern Taiwan. Data was collected through field observation and semi-structure interviewing over 5 months in 2004 .The comparative method (grounded theory) was used to analyze data. Five categories were revealed which included “Panic-stricken: due to unexpectedly news”, “Anticipation versus fear: unendurable waiting“,”Articulating by situation changes: calculating and planing”, “Stay calm: preparation for receving diagnosis” and” Relief but worring: the uncertain future”. Finally, “Anchor finding within uncertainty experience “was generated as a core issue. This theory of described how parents cope wth uncertainty and interacte with health care provider. It also explains the process of decreasing parents’ distress and increasing their bearing capacity before being disclosed the diagnosis.
In conclusion, the relevent interventions need to be established, especially in waiting time before CHT diagnosis is made. Implications for future studies in examining communication process between parents and health provider are suggested.

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