腫瘤為全球主要死因之一，其治療方式除傳統手術、化療與放療外，熱燒灼療法因具備微創、傷口小與復原期短等優勢，近年逐漸受到重視。腫瘤細胞對高溫較為敏感，當局部組織溫度超過42°C，即可有效誘導腫瘤細胞凋亡，達到治療效果。然而現有熱療系統常面臨設備體積龐大、能量供應受限與溫控穩定性不足等挑戰，限制其於可攜式與精準治療場域之應用。本研究提出一套基於模糊控制與無線傳能之手持式腫瘤熱燒灼系統，整合無線傳能模組、微控制器（NUVOTON M482）、K型熱電偶感測元件與限流電路，搭配Mamdani型模糊控制器進行溫度閉迴路控制。控制邏輯以溫度誤差與變化率作為輸入，輸出PWM信號動態調整加熱功率，強化系統於不同加熱條件下之穩態響應。系統經空針測試與豬肝組織實驗驗證，能於50°C至70°C操作範圍內穩定運行，平均穩態誤差控制於±2°C，燒灼區域具一致性且溫控反應迅速。整體系統具備體積小、功耗低與溫控準確等特性，未來可應用於床邊熱療或植入型治療裝置，為臨床腫瘤熱療提供一項具可行性與發展潛力之微型熱療平台。

Cancer is one of the major causes of death in the world. Thermal cauterization has gradually has gained attention in recent years due to its advantages of minimally invasiveness and short recovery time. Cancer cells are sensitive to high temperatures, and when the local tissue temperature exceeds 42 °C, apoptosis can be induced. However, the existing thermal therapy systems often face challenges such as large size of equipment, limited energy supply, and lack of stability in temperature control, which limit their application in portable and precise treatment fields. In this study, we propose a Integration of Wireless Power and Fuzzy Control in a Miniaturized Tumor Ablation Needle System, which integrates a wireless power supply module, a microcontroller (NUVOTON M482), a K-type thermocouple sensing element, and a current limiting circuit with a Mamdani type fuzzy controller for closed-loop temperature control. The control logic takes the temperature error and rate of change as inputs and outputs a PWM signal to dynamically adjust the heating power to enhance the system's stable response under different heating conditions. The system has been verified by a pig liver tissue experiment, and it can operate stably within the operating range of 50 °C to 70 °C. The average stability error is controlled within ±2 °C, and there is consistency in the cauterization area with rapid temperature control response. The overall system has the characteristics of small size, low power consumption and accurate temperature control, which can be applied to bedside thermal therapy or implantable therapy devices in the future, providing a miniature thermal therapy platform with feasibility and development potential for clinical tumor thermal therapy.

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