腫瘤電磁熱療是藉由高頻感應加熱器於體外產生一交變磁場，並對腫瘤細胞周圍的金屬針具進行高溫加熱，使針具快速升溫達到不同組織燒灼所需要之溫度，藉此殺死腫瘤細胞並達到熱療之效果。本論文之目標在建立一個可控制金屬針升溫幅度的高頻感應加熱系統之數位溫度回授控制電路，藉由偵測金屬針溫度及輸出電流來進行回授及穩定控制。透過微控制器做為數位控制核心，藉由頻率邊界及溫度偏移量之計算，以變速之頻率調變技術來控制全橋串聯諧振電路。精確且快速控制交變磁場的功率輸出，將電磁熱療用金屬針溫升控制在安全範圍之內。同時輔以一人機介面讓使用者設定系統相關參數及監測金屬針升溫情況，以達到即時控制之目的。經實驗結果證明，本數位回授控制系統確實可將金屬針升溫控制在正負5 ℃內，確保未來電磁熱療過程不對正常細胞產生影響。

Electromagnetic tumor hyperthermia is to create an alternating magnetic field in vitro by high-frequency induction heating machine, and this magnetic field can heat the metal needle surrounding tumor cells rapidly up to different temperatures required to cauterize different tissues, so that the tumor cells can be killed, with the effect of hyperthermia achieved. The main objective of this thesis is to design a digital temperature feedback control circuit for high-frequency induction heating system that can control the range of temperature of the metallic needle. In addition, this system will be able to detect the temperature and the current feedback signal for system stability control. The core of the system is based on a microcontroller, by the calculation of frequency boundary, full-bridge series resonant circuit was controlled by variable-speed frequency modulation technology. The results show that the system can generate fast and accurate output power, and heat the metallic needle within a safe temperature range. A GUI program that can be used to set system parameters and real-time monitor the temperature of the metallic needle. The experimental results show that the digital feedback system can be used to control the temperature of metallic needle to the preset-value with variant less than +/- 5 ℃ for electromagnetic hyperthermia applications.

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