腫瘤電磁熱療是藉由高週波加熱器在體外產生的交變磁場，對腫瘤細胞周圍的磁性物質做加熱，使磁性物質升溫至42℃至45℃之間，藉以殺死腫瘤細胞達到熱療的效果。本研究的主題在建立一個可控制磁性物質升溫幅度的大功率加熱系統，並在探頭處建構一組溫度回授訊號，使加熱參數數據化，並採用高速的微控制器做為數位控制的核心，藉由頻率調控技術控制全橋串聯諧振電路，精確且快速的控制交變磁場的功率輸出，將磁性物質升溫控制在安全範圍之內。經實驗結果證明，本數位回授控制系統確實可將磁性物質升溫控制在預設之溫度區間，以確保未來電磁熱療過程不對正常細胞產生影響。

Electromagnetic tumor hyperthermia is a therapeutic method providing an alternative magnetic field using a high-frequency induction heating machine that can heat magnetic substances around tumor cells. If the magnetic substance is heated between 42℃and 45℃, it can destroy the tumor cells. The main objective of this thesis is to design a high-powered heating system that can control the temperature range for the magnetic substance and create a temperature feedback signal on the applicator. In addition, this system will convert the critical heating parameter to digital values. The core of the system is based on a high-speed microcontroller using variable frequency to control a full-bridge series-resonant circuit. The heating results show that the system can generate fast and accurate output power, and can heat the magnetic substance within a safe temperature range. It shows that the digital feedback system can be used to control the temperature of magnetic substance to the preset temperature range for electromagnetic hyperthermia applications.

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