研究生: |
蘇柏翰 Su, Po-Han |
---|---|
論文名稱: |
應用於穿戴式心電訊號量測之運動偽影降低處理系統開發與高通三角積分調變器設計 Development of Motion Artifact Reduction System and Design of High-Pass Sigma-Delta Modulator for Wearable Electrocardiogram Measurement |
指導教授: |
李順裕
Lee, Shuenn-Yuh |
共同指導教授: |
陳儒逸
Chen, Ju-Yi |
學位類別: |
博士 Doctor |
系所名稱: |
電機資訊學院 - 電機工程學系 Department of Electrical Engineering |
論文出版年: | 2023 |
畢業學年度: | 112 |
語文別: | 英文 |
論文頁數: | 105 |
中文關鍵詞: | 穿戴式系統 、心電圖 、運動偽影 、高通三角積分調變器 、生理訊號擷取電路 、生理信號處理 、生理信號分析 |
外文關鍵詞: | Wearable system, ECG, motion artifact, high-pass sigma-delta modulator, biosignal acquisition circuit, biosignal processing, biosignal analysis |
相關次數: | 點閱:132 下載:0 |
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近年來,個人健康照護成為越來越受人矚目的議題,進而使得市場對於無線且可穿戴之生理訊號量測裝置有大量的需求。這些裝置具有潛力能處理幾項挑戰,例如人口老齡化帶來的巨大醫療保健需求、逐步增加的醫療成本、以及醫療專業人員的短缺。在多種生理資訊之中,心臟功能是最基本的量測項目,因為心血管疾病十幾年來都是全球的十大主要死因之一,此外,隨著國家的開發程度越高,心血管疾病在致死原因的排名中就越靠前段,甚至為第一名。而根據世界衛生組織的建議,盡早發現此疾病對於後續的諮詢與藥物管理很重要,為了檢測心血管疾病,監測心電訊號即是必須執行的項目,通過分析此訊號可以得知許多心臟活動的資訊,進而應用在疾病診斷或健康照護上。正因為此訊號的重要性,開發其穿戴式量測系統是研究趨勢之一,此類系統能讓使用者隨身穿戴,使得訊號量測較不受時間與場所限制,因而被期望為提供更完善健康照護的方案。
本篇論文將以穿戴式系統為主軸,心電為應用主題,分成兩大部分探討。第一部分實現一應用於心電感測衣物之運動偽影降低系統。此系統可分成三大區塊,即心電感測衣、訊號量測裝置與訊號處理演算法。心電感測衣整合之電極與訊號傳輸線採用導電紡織材料製作,目的為提供在長期使用的情境下較好的舒適度。訊號量測裝置之主體為感測心電與運動偽影參考訊號之前端電路,以及無線傳輸用之藍芽模組。訊號處理演算法則用於辨識心電訊號中的運動偽影並降低其影響,此部分對於乾式電極尤其重要,因為乾式電極並不使用導電凝膠與黏著劑來固定其與皮膚接觸之位置,所以運動偽影的影響比起傳統氯化銀電極更加嚴重。在與現有文獻比較下,所提出之系統除完整性較高之外,也能提供較好之定量結果。
第二部分則是提出一應用於心電訊號感測前端電路之高通三角積分調變器。穿戴式裝置之電源一般由電池供應,且小型裝置才能符合穿戴式之需求,這導致電池電量難以提高,因而穿戴式裝置所面臨的挑戰之一便是功耗。為了進一步降低現有高通三角積分調變器之功耗,本論文提出一新型高通積分器,使得主要功耗來源之放大器能被重複利用,進而在相同調變器階數下降低放大器數量。此外,可變前授係數亦被採用來增加調變器的動態範圍,藉此降低前級放大器所需規格,有望能進一步降低整體類比前端電路功耗。所提出之高通三角積分調變器以TSMC 0.18μm standard CMOS 製程製造,其效能與現有文獻比較下除具有較低的功耗外,也提供較寬的動態範圍。
本論文包含一個系統與一個電路,皆是在穿戴式心電量測主題下進行探討,期望未來進一步優化設計後,對於穿戴式健康照護的發展能做出貢獻。
In recent years, personal healthcare has become increasingly popular. This popularity has led to significant demand for wireless and wearable physiological signal measurement devices. These devices have the potential to address several challenges, such as the enormous healthcare needs of an aging population, increasing healthcare costs, and the shortage of healthcare professionals. Among many types of physiological information, cardiac function is the most essential item to be monitored because cardiovascular disease has been one of the top 10 leading causes of death worldwide for more than a decade. Additionally, cardiovascular disease has a higher or even highest rank in the list of causes of death with more income in a country. According to the suggestion from World Health Organization, early detection of the disease is important for subsequent counseling and medication management. To detect cardiovascular disease, monitoring of electrocardiogram (ECG) signal is essential. By analyzing this signal, a lot of information about heart activity can be obtained, which can be used for disease diagnosis or healthcare. Because of the importance of this signal, developing wearable systems for measuring it is one of the research trends. These systems can be carried by the user easily, making the signal measurement less restricted in time and place, and thus are expected to be the solutions to provide better healthcare.
This dissertation focuses on the wearable systems used for measuring ECG signals and is divided into two main parts to discuss the above issue. The first part proposes a motion artifact reduction system for ECG measuring clothing. This system can be divided into three major blocks, namely, ECG measuring clothing, signal acquisition device, and signal processing algorithm. The electrodes and signal transmission lines of the ECG measuring clothing are made of conductive fabric materials to provide better comfort under long-term usage. The main parts of the signal acquisition device are the front-end circuit for sensing ECG and motion artifact reference signals and the Bluetooth module for wireless transmission. The signal processing algorithm is designed to identify the motion artifacts in the ECG signals and reduce their effects. This part is especially important for dry electrodes. Compared with conventional Ag/AgCl electrodes, the motion artifacts are more severe when using dry electrodes because conductive gel and adhesive are not adopted to fix the electrodes on the skin. In comparison with the existing literature, the proposed system is more complete and can provide better quantitative results.
In the second section, a high-pass sigma-delta modulator is proposed for the front-end circuit of ECG measurement. One of the challenges for wearable devices is power consumption because the power is generally supplied by batteries. The device size needs to be small to meet the requirement of the wearable application, which makes the battery power difficult to increase. To further reduce the power consumption of the existing high-pass sigma-delta modulator, this dissertation proposes a new high-pass integrator that allows the amplifier, which is the main source of power consumption, to be reused. Therefore, the number of amplifiers can be reduced with the same order of modulator. In addition, programmable feedforward coefficients are also used to increase the dynamic range of the modulator, thus reducing the specification requirement of the pre-amplifier, which is expected to further reduce the overall power consumption of the analog front-end circuit. The proposed high-pass sigma-delta modulator is fabricated in TSMC 0.18μm standard CMOS process. The measurement results show a wider dynamic range with lower power consumption compared with the existing literature.
This dissertation consists of one system and one circuit, and they are within the theme of wearable ECG measurement. It is expected that these studies will contribute to the development of wearable healthcare after further optimizing the design in the future.
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