拇指腕掌關節是上肢最常發生退化性關節炎的位置。在過去許多文獻中探討造成退化性關節炎的原因。其原因主要是韌帶鬆弛，而造成關節承受不正常壓力、應力，而產生退化。因為拇指腕掌關節為馬鞍型構造，而主要的穩定關節結構的是韌帶，其中以前斜韌帶以及背橈韌帶較為重要。而對於腕掌關節退化性關節炎的治療方式主要有非侵入性治療以及手術治療，當非侵入性治療對於關節炎緩解無效時，手術治療會介入，手術的方式為後側入路 (posterior approach)跟前側入路 (anterior approach)，後側入路的方式會將背橈韌帶切開，處理拇指腕掌關節問題，前側入路的方式會將前斜韌帶切開，處理拇指腕掌關節問題，在手術過程中會將外展拇長肌做部分切開，使手術方便進行。所以此篇研究在探討前斜韌帶跟背橈韌帶對腕掌關節的穩定性影響，以及切開不同程度的外展拇長肌對腕掌關節穩定性影響。
本實驗研究以大體實驗去討論前斜韌帶跟背橈韌帶對腕掌關節穩定度影響。將大體分為兩組，一組為切前斜韌帶，另一組為背橈韌帶，在大拇指與掌面夾30度的姿勢下，利用客製化模擬器帶動大拇指做內縮，外展，伸直，屈曲，旋繞的動作，同時利用電磁場動作擷取系統收集運動過程中的資料，分別在原始狀況、切除韌帶的狀況、切除韌帶跟部分的外展拇長肌的狀況以及切除韌帶跟全部的外展拇長肌的狀況下去帶動動作，計算第一掌骨關節面幾合中心相對於梯型骨關節面幾何中心移動的方向位移量。
從結果來討論，在外展動作下，切前斜韌帶，會增加尺側的位移量，而切背橈韌帶，背側位移量會減少; 在內縮動作上，在切前斜韌帶，會增加背側的位移量，而切背橈韌帶，腹側位移量會增加;在旋繞的動作下，切除兩條韌帶後，其第一掌骨關節面幾合中心所環繞的面積比在沒有切除韌帶所所環繞的面積大，在伸直動作下，切前斜韌帶，會增加尺側的位移量，而切背橈韌帶，橈側位移量會增加，在屈曲的動作下，切前斜韌帶，會增加腹側的位移量，而切背橈韌帶，背側位移量跟遠端位移量會增加。

The osteoarthritis of thumb TMC joint is the most popular upper limbs arthritis [1]. TMC osteoarthritis might be caused from continuous load of compression, deformity by shear force, wear of articular surface [2]. Several studies have demonstrated the wear of the TMC surface, causing joint instability and ligament attenuation. The articular surface of the joint is a saddle type and the ligaments are very important for the stability of the TMC joint [3]. The treatments for osteoarthritis of the TMC joint includes both operative and non-operative treatments. When a non-invasive treatment for arthritis fails, surgical treatment is used. The operative methods include posterior approach and the anterior approach. The posterior approach sections the dorsoradial ligament. The anterior approach sections the anterior oblique ligament . During operative procedures, the operator detaches the partial APL to expose the TMC joint. Therefore, this study investigates the anterior oblique ligament and the dorsoradial ligament for the stability of the TMC.
This study performs cadaveric experiments to investigate the anterior oblique ligament and the dorsoradial ligament for the stability of the TMC joint. The experiment has two groups: AOL group and DRL group. A custom design simulator is used in the experiment. The cadaveric hand is moved in abduction, adduction, flexion, extension and circumduction. The movements are collected under the intact, sectioned ligament, sectioned ligament and partial APL, and sectioned ligament and whole APL. This study calculates the translation of the geometric center of the matecarpal articular surface for the segment coordination system of trapezium.
From our results, the ulnar translation increases with sectioned AOL and dorsal translation decreases with sectioned DRL as moving in abduction. The dorsal translation increases with sectioned AOL, and the volar translation increases with sectioned DRL as moving in adduction. The areas increase under sectioned AOL and DRL. The ulnar translation increased with sectioned AOL, and the radial translation increased with sectioned DRL during extension. The volar translation increased with sectioned AOL, and the dorsal and distal translation increased with sectioned DRL as moving in flexion.
From our result, the translation is investigated with the different level of detaching APL after sectioning DRL and AOL. There is no significance with the different degrees of APL sections in the AOL group and DRL group.

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