在細胞組織學上，研究者判斷其培養物生長的過程健全與否，通常使用光學顯微鏡擷取資訊，觀察其形態上的變化近而進行分析，本研究利用電學歐姆原理製作電阻抗系統，測量其相關的電特性分佈情況，希望提供組織領域研究者一個有別以往的有用資訊做為判斷之參考，而研究架構包含了兩個部分，分別是電阻抗系統與電極陣列之設計；電阻抗系統包括了數位震盪電路、電流產生器、電壓量測電路、傳輸介面等電路設計，其具可單獨設定三十二個電流源及差值量測方式減少直流值誤差、量測電壓值解析度為十六位元等優點；具有電極陣列的培養皿則是利用壓克力板覆蓋上金製作而成的電極片，其具有生物相容、可重覆利用、導電性佳、符合消毒流程、隔離因電極背端電流所造成擾流等特點，另外，為了便利研究者量測，因而設計一台可同步連結電阻抗系統與電流陣列的手動式移動機構，研究者可經由改變機構垂直與水平方向，進而移動使得放置於機構上的培養皿能與光學顯微鏡平台的結合，同時取得型態與阻抗上的資訊。

　　In the past, Cell researchers used optical microscope to fetch whether the growth of the culture is well developed or not by observing the change of its morphological change. In this research we create an impedance system based on Ohm law to measure its related impedance distribution. Furthermore, we hope to offer more advanced information by using other method in our research.
　　There were two parts included in this research; they were “the design of EIT system” and “the design of electrode array”. EIT system includes Digital Oscillator, Current Generator, Voltage Measurement, and I/O Interface Circuits. Some advantages of the impedance system were: (1).Each of the thirty-two electrodes can be set or closed individually and the method of differential voltage measurements can reduce the error of D.C value. (2).The resolution of voltage measurement value is 16 bits. Also, the culture with electrode array is made from some electric plates that we use some acrylic plate coating with metal. The advantages of the plate for tissue culture dish are its biocompatibility, resource reuse, qualified antiseptic ethanol process, and isolation from the disturbances of the reverse current. Besides, we design a manipulation system to connect EIT system and electrode-array system together for more convenience measuring. Through the manipulation system we can also change the direction of the culture from vertical to horizontal to proper position on optical microscope in advance to fetch the morphological and electrical information and also information about EIT system.

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