一般而言，醫院對於檢驗細菌所需時間都有過久以及檢測繁複的問題，因此在本研究結合微機電製程技術，將檢驗平台微小化與檢測時間縮短，設計以電動力學為基礎之微濃縮器平台，利用微奈米科技與電動力學結合應用在醫學檢驗，能在十分鐘內達到濃縮之效果。
本研究以電動力學為主來設計環狀指叉型電極平台，藉由交流電之非均勻電場產生介電泳力與交流電滲流力結合，操控溶液中的粒子使之傳輸並聚集，並應用於生物粒子如細菌即時濃縮之研究。當細菌溶液(~ 100L)滴至微濃縮平台上，施加交流訊號(120 Vpp, 1 kHz)於晶片上，使溶液受到電動力學作用產生交流電滲流與介電泳力，使溶液中的細菌受到流體帶動往電極中心傳輸與聚集，無須外加微注射器產生連續流動並濃縮的效果。於研究中使用Vibrio、Escherichia coli以及Staphylococcus aureu為例，施加理想交流電壓與頻率，細菌受到交流電滲流與介電泳力相互作用，使溶液中的細菌產生傳輸與濃縮現象。約十分鐘可分辨出不同濃度的細菌(106~ 104 CFU/mL)。依此功能，未來將有可能應用到菌尿症等相對低濃度細菌的快速檢驗上。

In general, there are some problems of detection in hospital such as time consuming and complicated detection. In this research, a micro-concentrator platform for medical combined micro electro mechanical systems (MEMS) and electrokinetic is designed, then the sample in solution can be concentrated in few minutes.
In this study, an electrokinetic-based ring interdigitated electrode platform was designed. Combined dielectrophoresis (DEP) generated by non-uniform electric field and AC electroosmotic flow (ACEO) to manipulate particles in the solution to transmit and concentrated, and applied to biological particles such as bacteria immediately concentrated.
When the bacteria solution (~100 L) was dropped to micro-concentrator platform and AC signal (120 Vpp, 1 kHz) is applied to the device, the bacteria in the solution were transmitted and concentrated by AC electroosmotic flow (ACEO) and dielectrophoresis (DEP) without external micro-syringe. In this study, Vibrio, Escherichia coli and Staphylococcus aureu were used for transmission and concentration by interaction of ACEO and DEP applied appropriate AC signal and frequency. In ten minutes, the different concentrations of bacteria (106 ~ 104 CFU/mL) could be distinguished. In the future, the platform may be applied to the low concentration detection, such as rapid test on urinary tract infection, etc.

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