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研究生： 陳怡達
Chen, Yi-da
論文名稱： 無線子宮收縮信號監視系統之實現
Implementation of a Wireless Monitoring System for Uterine Contractions
指導教授： 陳天送
Chen, Tain-song
學位類別： 碩士
Master
系所名稱： 工學院 - 醫學工程研究所
Institute of Biomedical Engineering
論文出版年： 2008
畢業學年度： 96
語文別： 中文
論文頁數： 67
中文關鍵詞： 子宮收縮 、8051 、PDA 、藍芽
外文關鍵詞： Bluetooth, PDA, 8051, Uterine Contractions
相關次數： 點閱：81  下載：4 
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    • 在臨床的產檢中，子宮收縮信號是個非常重要的生理參數，藉由測量收縮頻率與收縮強度，可使臨床醫護人員更了解胎兒的狀況；如果子宮異常收縮嚴重，甚至會引起早產或是流產。但是臨床人員通常只有在產檢時，才可得知孕婦子宮收縮狀況，沒辦法長時監視子宮收縮活動。有鑑於此，本研究提出一套以PDA手機為監視系統的儀器，希望藉由長時間記錄子宮收縮信號與頻率，減低早產的可能性。
    系統硬體由壓力擷取系統與無線傳輸系統所組成，壓力擷取系統由8051微處理器與壓力感測電路所構成，無線傳輸系統則為藍芽發射模組與PDA手機所構成。系統的量測方式為，利用自行製作的感測器與壓力擷取電路擷取子宮信號，再由8051控制藍芽發射模組傳送無線信號；接著近端PDA手機接收訊號，並在手機螢幕上顯示訊號波形。根據臨床實驗結果得知，無線傳輸距離到達7m，增加受測者的活動性，同時也可偵測子宮收縮異常信號，有效的紀錄收縮強度與頻率，使臨床醫護人員更了解孕婦的子宮活動情形，及時做出診斷。

    During the childbirth examination, uterine contraction signal is very important parameter, by measuring frequency and intensity of contraction, which can provide the fetal status to the clinical personnel. If the uterus contracts intensively, she will probably cause premature delivery or miscarriage. However clinical personnel can learn the uterine contraction of pregnant women only by childbirth examination, without long-term monitoring the uterine contraction activity. The aim of my study is to set up a PDA cell-phone monitoring system, hopefully by long-term measuring contraction signals could be utilized the possibility of premature delivery.
    The systematic hardware consists of pressure acquisition system and wireless transmission system, pressure acquisition system consists of 8051 microprocessor and pressure circuit, wireless transmission system consists of Bluetooth module and PDA cell-phone. The system can be applied to pressure sensor for acquiring signal, 8051 microprocessor controls Bluetooth module to transmit wireless signal, then nearly end PDA cell-phone receives the signal and shows the waveform on the screen of the cell-phone. According to the clinical result, the wireless transmission distance can reach up to 7m, not only can affect the activity of the person hardly but also can detect unusual contractions at the same time, to record frequency and intensity of contraction effectively, and let clinical personnel understand the uterus activity of the pregnant woman, making diagnosis can detect in time.

    中文摘要...……………………………………...…………………….………I 英文摘要…………………………………………...…………………...……II 致謝……………………………………….…………………………...……III 目錄……...………………………………………………..…….……...……IV 圖目錄…...………..……………………………………….……….………VII 表目錄………..…………………………………..……………………...…..IX 第一章 緒論…………………………………………………………...……..1 1-1 前言……………………………………………….………..….........1 1-2 研究背景………………………………………….………..……….2 1-3 研究動機…………………………………………………...……….3 1-4 文獻回顧…………………………………………………...……….4 1-5 章節提要………………………………………………...……….. 11 第二章 系統原理……………………………………………...……………12 2-1 子宮收縮與早產……………………..………………. ...………...12 2-2 子宮收縮的臨床量測方法…………..……………...…..………...13 2-3 微處理機AT89S51簡介………………….……………..………. 15 2-3-1 微處理機開發軟體Keil-A51………….………....…………15 2-4 壓力感測器簡介………………….…………………...……...…...16 2-4-1 壓電訊號轉換原理……………..………………………..…17 2-5 無線技術介紹…………………………..……………..……..…...18 2-6 藍芽的起源………………..……………………..…………..…...19 2-6-1 藍芽技術特色……………..…..………………….………...20 2-6-2 藍芽訊號發射模組………………..…………….……….....21 2-7 ASUS-P525 PDA手機…………………………..…………..….….22 2-7-1 PDA手機開發軟體簡介……………………………...……..23 2-7-2 Microsoft Visual Studio 2005軟體介紹……………....……..23 第三章 系統設計…………………………………………...………............25 3-1 系統架構………………….…………………………………...…..25 3-1-1 系統硬體驅動流程說明..………..….……………………...26 3-2 類比訊號處理流程說明………………...………………………...26 3-2-1 放大電路設計..………………………………………...…...27 3-2-2 低通濾波電路設計原理與設計..……………………...…...28 3-2-3 電源電路設計……………….….………..…………….…...29 3-2-4 校正電路設計..…………………………………...………...30 3-3 數位電路設計…………….………….... .…………………….…..31 3-4 微處理機程式設計……….………………………………….........33 3-5 無線傳輸系統設計……….…………………………………..…...34 3-5-1 發射端程式說明.…….………………………………...…...35 3-5-2 接收端程式說明…….………………………………….......36 第四章 系統驗證與結果…………..……..…………………………...……37 4-1 系統功能說明………………………………………………...…...37 4-1-1 手機介面功能說明..………………………………...……...40 4-2 系統驗證測試……………………………………………...……...42 4-2-1 傳輸距離測試………………………………...………….....42 4-2-2 系統儀器校正實驗…………………………...………….....45 4-2-3 腹部壓力測試………………………………...………….....47 4-3 臨床量測……….…………………………………....………….....50 第五章 結論與未來展望………………………………………...…………54 5-1 結論………………………………………………...……………...54 5-2 論文整理………………………………………………...………...54 5-3 未來展望……………………………………………………...…...55 參考文獻……………………………………………………………….57 附錄………………………………………………………………….…59 圖目錄 圖1-1 感測元件.........................................................................................4 圖1-2 信號擷取電路.................................................................................5 圖1-3 感測器.............................................................................................5 圖1-4 系統完成圖.....................................................................................6 圖1-5 受力曲線圖.....................................................................................6 圖1-6 系統架構圖.....................................................................................7 圖1-7 無線傳輸系統示意圖.....................................................................8 圖1-8 系統完成圖.....................................................................................9 圖1-9 訊號擷取電路................................................................................ 9 圖1-10 無線傳輸系統示意圖.................................................................10 圖1-11 系統電路完成圖.........................................................................10 圖2-1 收縮壓力與子宮血流關係圖……………………………...........12 圖2-2 外部子宮收縮壓力測量示意圖…………………………….…..14 圖2-3 內部子宮收縮壓力測量示意圖………………………………...14 圖2-4 Load Cell........................................................................................16 圖2-5 Westons Electric bridge..................................................................18 圖2-6 藍芽模組.......................................................................................22 圖2-7 ASUS-P525 PDA手機...................................................................22 圖3-1 系統架構圖...................................................................................25 圖3-2 類比訊號處理流程.......................................................................27 圖3-3 AD620腳位圖................................................................................28 圖3-4 Sallen-Key濾波器電路模型.........................................................29 圖3-5 系統電源電路...............................................................................30 圖3-6 減法器電路...................................................................................31 圖3-7 數位電路功能...............................................................................32 圖3-8 數位電路圖………………...........................................................33 圖3-9 微處理器程式流程圖...................................................................34 圖3-10 無線系統示意圖.........................................................................35 圖3-11 接收端程式流程圖.....................................................................36 圖4-1 系統實作電路...............................................................................38 圖4-2 系統實作電路...............................................................................38 圖4-3 感測器與帶子...............................................................................40 圖4-4 手機面板設計...............................................................................40 圖4-5 判斷收縮程式流程圖...................................................................41 圖4-6 密閉空間內部空間圖...................................................................42 圖4-7 戶外空間圖...................................................................................44 圖4-8 儀器校正流程圖...........................................................................46 圖4-9 儀器受力曲線圖...........................................................................47 圖4-10 系統實際佩帶圖.........................................................................48 圖4-11 手機端訊號圖.............................................................................49 圖4-12 受測者腹部壓力波形顯示.........................................................49 圖4-13 臨床實驗量測圖……………………...………………………..50 圖4-14 臨床實驗流程……………….………………………………....51 圖4-15 實驗波形圖…………………………………….........................52 表目錄 表2-1 早產五大前兆...............................................................................13 表2-2 感測器特性...................................................................................17 表2-3 無線傳輸技術比較.......................................................................19 表2-4 藍芽模組特性表………………………………….......................22 表4-1 系統功能說明表...........................................................................37 表4-2 系統電路特性表...........................................................................39 表4-3 室內傳輸距離測試表…………………….…………..………....43 表4-4 戶外傳輸距離測試表………………………………..……….....45 表4-5 儀器量測結果(1)………...……………………...........................46 表4-6 儀器量測結果(2)…………..…………..…………......................47 表4-7 受測者資料………………………………………………...........51 表4-8收縮信號統計……..………..…………………………………….53

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