前言：要維持和改善健康，主要策略為「健康促進」和「自我照顧」。其中「自我照顧」是個人、家庭與社區為達到促進健康所表現的活動，並且亦為健康照護系統的基礎。個體不僅可以藉由自我照顧來促進健康、維持健康、預防疾病、發現疾病及治療疾病，更可得以掌控健康狀況。因此，為了改善慢性病，「自我照顧」將是重要的策略，而併服飲食補充品的行為與其相關訊息來源之研究自然將成為健康照護系統中極重要的議題。
目的：本研究綜合國內外相關文獻探討，並配合實證研究結果及量性分析了解冠心病患者使用飲食補充品包括服用維他命、植物性營養品、草本漢方生藥(中藥)等的訊息來源，並進一步探討社會人口學與各種消息來源之間的關係，此結果期望作為日後健康照護者在進行病患照護與衛教工作之餘，能深入了解患者取得飲食補充品的消息管道並透過整合患者的處方用藥與服用的飲食補充品種類，進而降低可能的藥物與飲食補充品、草本漢方生藥間的交互作用。
方法：本研究採立意取樣，以冠心病患者為研究對象，自民國96年6月至96年9月期間，於台南市社區健保藥局以結構式問卷進行收案。第一階段選取研究藥局家數(n=26)，第二階段選取符合條件的有效樣本(n=502)作為分析的對象。
結果：502位研究樣本中，女性佔51.79%，男性佔48.20%。年齡分布自40歲至70歲以上，平均年齡為60.32歲，教育程度方面，以高中(職)居多佔45.42%，疾病史方面，八成四的受訪者同時合併其他疾病，其中以併發高血壓疾病為首要，其次為高膽固醇及糖尿病，並且將近41%的患者者服用多於5種以上的慢性處方藥品。同時，502位研究樣本中，3.38%的患者表示在過去兩星期內完全沒有使用過任何一種補充品， 96.61%的患者表示在過去兩星期內曾經使用過任何一種補充品。其中，九成一的患者曾經服用植物性營養品，將近六成的患者曾經服用維他命，八成的患者曾經服用草本漢方生藥。但是，分析結果也得知患者服用任何補充品並不會主動告知醫生，其中以維他命及草本漢方生藥的使用者為居多。在影響的人物或頻道方面，紅麴與中成藥的使用者最主要受到「電台」的影響；綜合維他命則以「電視」為主要影響因素；而銀杏、大豆異黃酮及單方維他命則以「藥師」為主要影響因素；另外，草本漢方生藥中的中藥飲片方面主要則是受到「家人」的影響居多，而醫師在患者使用草本漢方生藥方面並無任何影響力。
討論：本研究所發現女性患者比男性較普遍化使用補充品，而在每個年齡層上所使用的補充品方面不盡相同，只有草本漢方生藥普遍被中老年患者接受使用。至於相關的影響管道方面，「電台」、「藥師」對患者使用補充品上相較於其他影響因素其影響力較大。從文獻裡頭我們已知紅麴和銀杏等都是屬於預防心血管疾病的補充品，但是當與抗凝血劑、降血脂藥物合併使用時會增加其副作用、交互作用甚至可能會傷害肝臟與腎臟，若是健康照護者在第一時間內能敏銳觀察並整合患者透過其他管道取得的補充品品項，則能減少各種可能的潛在交互作用。

Background：In order to maintain and improve health, the main strategy is “health promotion” and “self-care”. For achieving the goal of promoting health, " self-care" is the demonstration by individuals, families and the communities; it is also the base of health care system. Individuals can promote and maintain health, but also can prevent, discover and treat diseases by self-care; they may be able to control health. Therefore, in order to improve chronic illness, “self- care” will be an important strategy, but the behavior of taking dietary supplements and the research on the source of related information will become a more important subject in health care system.
Objective：The research synthesizes both domestic and foreign related literature discussion, and coordinates practical study findings as well as the quantity analysis for understanding the information source for patients, who are diagnosed with coronary heart diseases, taking dietary supplements, including taking vitamins, plant nutriment and Chinese herbs and so on. Further, this research aims to discuss the correlation between social demography and information source. According to the result of this research, caretakers are expected to have a further understanding about the channels, through which the patients obtain the information source of the dietary supplements, while they involve themselves in taking care of the sickness and engaging in health education. Also, via the integration of patients’ prescribed medicine and dietary supplements, the potential interaction among medicine, dietary supplements and Chinese herbs can be reduced.

Method： The approach of this research is based on purposive sampling, and patients who are diagnosed with coronary heart disease are targeted. From June to September in 2007, the structural questionnaire is employed for collecting cases in health insurance pharmacies in communities located in Tainan city. In the first stage, the major work is to select the number (n=26) of the pharmacies for the studies. In the second stage, the key point falls on selecting effective samples (n=502), which are targeted for analysis.
Result：Among the total 502 samplings, female accounts for 51.79%, and male makes up 48.20%. The age levels range from 40 years old to over 70 years old. The average age is 60.32 years old. In the aspect of education levels, most of the interviewees of the questionnaire have high school degree, accounting for 45.42%. Regarding the history of disease, 84% of the interviewees have other combined diseases. Hypertension is ranked as number one, the followings are high cholesterol and diabetes. Nearly 41% of the patients take more than 5 kinds of prescribed medicine for their chronic illness. Meanwhile, 3.38% of the patients indicated that they have not taken any supplements for the past two weeks. 96.61% of the patients pointed out that they have not taken any supplements for the past two weeks. Among the interviewees, 91% of the patients have taken plant nutriment; nearly 60% of the patients have taken vitamin and 80% of the patients have taken Chinese herbs. Nevertheless, the result of the analysis also finds that patients who take supplements do not inform their doctors of what they take by themselves, especially those who take vitamin and Chinese herbs. When it comes to the characters or channels having strong influence, the users of red yeast and Chinese herbal medicine(Over The Counter) are mainly affected by “radio stations”. Multivitamins takers are primarily affected by “television”. As for users of gingko, soybean isoflavones and single vitamin are affected by “pharmacists". Moreover, in the aspect of Chinese herbal medicine, the major effect factor for the users of Chinese native medicine comes from ”family”. However, “doctors” don’t have any influence on patients who take Chinese herbal medicine.
Discussion and Conclusion：From the study, we notice that there are more female patients, compared with male ones, take supplements. The supplements that each age level takes are not exactly the same. There is only Chinese herbal medicine that is generally accepted by middle-aged and senior patients. Regarding the related factors with effect, “ radio stations”and ”pharmacists ”, compared with other factors, have stronger influence on patients who take supplements. From literatures, we know that Red yeast; Gingko and Vitamin E have a function to prevent cardiovascular diseases. However, it doesn’t mean that they are completely safe for patients when they take them, combining with Anticoagulants and Statins. Under this condition, it might increase side effect, interaction or harm patients’ liver and kidney . Therefore, if caretakers are prompt to have a sharp observation at the very beginning and integrate the channels, through which patients get the supplements, it can reduce each potential interaction between dietary supplements and medicine.

Anderson, D. L., Shane McWhorter, L., Crouch, B. I., & Andersen, S. J. (2000). Prevalence and patterns of alternative medicine use in a university hospital outpatient clinic serving rheumatology and geriatric patients. Pharmacotherapy, 20, 958-966.
Anderson, J. G. (2004). Consumers of e-health: Patterns of use and barriers. Social Science Computer Review, 22(2), 242-248.
Angelo, A. I., Giulia, D. C., Francesca, B., & Edzard, E. (2005). Cardiovascular pharmacotherapy and herbal medicines: the risk of drug interaction. International Journal of Cardiology, 98, 1-14.
Astin, J., Pelletier, K., Marie, A., & Haskell, W. (2000). Complementary and alternative medicine use among the elderly persons: One-year analysis of a Blue Shield Medicare supplement. J Gerontol Med Sci, 55A, M4-M9.
Astin, J. A. (1998). Why patients use alternative medicine: results of a national study. JAMA, 279, 1548-1553.
Astrand, P. O., & Rohdal, K. (1977). Textbook of work physiology. New York, Mc Graw-Hill., 143-205
Atkin, C., & Wallack, L. (1990). Mass communication and public health: Complexities and conflicts. Newbury Park, CA: Sage.
Awad, A. I., & Eltayeb, I. B. (2006). Self-medication practices in Khartoum State, Sudan. Eur J Clin Pharmacol 62, 317-332.
Bailey, D. G., & Dresser, G. K. (2005). Natural products and adverse drug interactions. CMAJ 170, 1531-1532.
Balluz, L., Kieszak, S. M., Philen, R. M., & Mulinare, J. (2000). Vitamin and mineral supplement use in the United States. Arch Fam Med, 9, 258-262.
Barnes, P. M., Powell-Griner, E., McFann, K., & Nahin, R. L. (2004). Complimentary and alternative medicine use among adults., . United States 2002 Adv Data, 343, 1-19.
Bensoussan, A., Myers, S. P., Drew, A. K., Whyte, I. M., & Dawson, A. H. (2002). Development of a Chinese Herbal Medicine Toxicology Database. Clinical Toxicology, 40(2), 159-167.
Brashers, D. E., Goldsmith, D. J., & Hsieh, E. (2002). Information seeking and avoiding in health contexts. Human Communication Research, 28, 258-271.
Brian, A. (2004). Counseling Patients on Mass Media and Health. Medicine and Society, 69(11).
Brodie, M., Kjellson, N., Hoff, T., & Parker, M. (1999). Perceptions of Latinos, African Americans, and Whites on media as a health information source. The Howard Journal of Communication, 10, 147-167.
Brown, B. G., Zhao, X. Q., & Chait, A. (2001). Simvastatin and niacin, antioxidant vitamins or the combination for the prevention of coronary disease. N Engl J Med 345, 1583-1592.
Carmel, M. H., James, C. M., & Glenda, F. F. (2001). Benefits and Risks of Self Medication. Drug Safety 24(14), 1027-1037.
Castelao, J. E., Yuan, J. M.,Gago-Dominguez, M., Skipper, P.L.,Tannenbaum, S. R.,Chan, K. K., Watson, M. A.,& Bell, D. A. et al. ( 2004). Carotenoids/vitamin C and smoking-related bladder cancer. International Journal of Cancer 110(3), 417-23.
Catherine, C. P., Peter, A., & Lauren, E. (2004). Incidence and severity of potential Drug-Dietary supplement interactions in primary care patients. Arch Intern Med, 164, 630-636.
Chan, K. (2003). Some aspects of toxic contaminants in herbal medicines. Chemosphere, 52, 1361-1371.
Chang, H. Y., Wallis, M., & Tiralongo, E. (2007). Use of complementary and alternative medicine among people living with diabetes：literature review. Journal of Advanced Nursing, 58(4), 307-319.
Cherniack, E., Senzel, R., & Pan, C. (2001). Correlates of use of alternative medicine by the elderly in an urban population. J Altern Complement Med, 7, 277-280.
Chuang, C. H., & Hsieh, W. S. (2007). Chinese herbal medicines used in pregnancy：a population-based survey in Taiwan. Pharmaco-epidemiology and drug safety 16, 464-468.
Chung, V., Wong, E., WOO, J., Lo, S. V., & Griffiths, S. (2007). Use of traditional Chinese Medicine in the Hong Kong Special Administrative Region of China. The Journal of alternative and complementary medicine, 13, 361-367.
Conner, M., Kirk, S. F. L., Cade, J. E., & Barrett, J. H. (2001). Why do women use dietary supplements? The use of the theory of planned behavior to explore beliefs about their use. Social Sci.Med., 52, 621-633.
Corbin, W. L., & Shapiro, H. (2002). Physicians want education about complementary and alternative medicine to enhance communication with their patients. Arch Intern Med, 162, 1176-1181.
Cotten, S. R., & Gupta, S. S. (2004). Characteristics of online and offline health information seekers and factors that discriminate between them. Social Science & Medicine, 59(9), 1795-1806.
Crawford, L. M., & D.V.M. (2002). Dietary Supplement Strategic Plan Cost Out. U. S. Food and Drug Administration Center for Food Safety and Applied Nutrition.
Crisell, A. (1994). Understanding radio(2nd edn) London:Rourledge.
Cui, Y., Shu, X. O., Gao, Y., Wen, W., Ruan, Z. X., Jin, F., et al. (2004). Use of complementary and alternative medicine by Chinese women with breast cancer. Breast Cancer Research and Treatment, 85, 263-270.
David, N. J.,Muhammad, M., Alexander, K., Andreas, L.,& Donald, A.R.( 2003). Drug-Drug Interactions Among Elderly Patients Hospitalized for Drug Toxicity. JAMA, 289, 1652-1658.
Department of Health and Human Services, Office of the Surgeon General (2004). Bone health and osteoporosis:a report of the Surgeon-General. Rockville: US
Digant, G., Christopher, G. L., Timothy, C. B.,& James, F.G.( 2005) The use of dietary supplements in a community hospital comprehensive cancer center: implications for conventional cancer care. Support Care Cancer, 13, 912-919.
Dolan, G., Iredale, R., Williams, R., & Ameen, J. ( 2004). Consumer use of the Internet for health information: A survey of primary care patients. International Journal of Consumer Studies, 28, 147-153.
Dutta-Bergman, M. (2003). Trusted online sources of health information: Differences in demographics, health beliefs, and health-information orientation. Journal of Medical Internet Research, 5.
Egede, L., Ye, X., Zheng, D., & Silverstein, M. (2002). The prevalence and pattern of complementary and alternative medicine use in individuals with diabetes Diabetes Care, 25(2), 324-329.
Eisenberg, D. M., Davis, R. B., Ettner, S. L., Appel, S., Wilkey, S., & Van Romapay, M. (1998). Trends in alternative medicine use in the united state, 1990-1997：Results of a follow-up national survey. JAMA 280(18), 1569-1575.
Emslie, M., Campbell, M., & Walker, K. (2005). Family Medicine Complementary therapies in a local healthcare setting. Part1：is there real public demand ? Complementary Therapies in Medicine 13(1), 16-24.
Eskin, S. B. (2001). Dietary supplements and older consumers Data Digest Washington, DC: AARP Public Policy Institute, 33, 51-59.
Felicia, E. M. (2005). The importance of news media in pharmaceutical risk communication: proceedings of a workshop. Pharmacoepidemiology and drug safety, 14, 297-306.
Foster, D., Phillip, R., Hamel, M., & Eisenberg, D. (2000). Alternative medicine use in older Americans. J Am Geriatric Soc, 48, 1560-1565.
Frank, E., Bendich, A., & Denniston, M. (2000). Use of vitamin-mineral supplements by female physicians in the United States. Am. J. Clin. Nutr. , 72, 969-975.
Fugh-Berman, A. (2000). Herb-drug interactions. Lancet, 355, 134-138.
Geller, S. E., Studee, L., & Chandra, G. (2005). Knowledge, attitudes, and behaviors of healthcare providers for botanical and dietary supplement use for postmenopausal health. Menopause, 12, 49-55.
Giveon, S. M., Uberman, N., Klang, S., & Kahan, E. (2004). Are people who use “natural drugs” aware of their potentially harmful side effects and reporting to family physician? Patient Education Counseling 53, 5-11.
Goldstein, M. R. (2000). Effects of dietary phytosterols on cholesterol metabolism and atherosclerosis. Am J Med, 109, 72-73.
Hart, A., Henwood, F., & Wyatt, S. (2004). The role of the internet in patient-practitioner relationships: Findings from a qualitative research study. Journal of Medical Internet Research, 6(3), e36.
Helmut, L., Harry, S., Giuseppe, D. L., Caspar, B., Joep, D., Klaus, K., & Pasalary,M.N., et al. (2004). Folate Therapy and In-Stent Restenosis after Coronary Stenting. N Engl J Med, 350, 2673-81.
Hennekens, C.H., Buring, J.E., Manson, J.E., Stampfer, M., Rosner, B., & Cook, N.R.,( 1996). Lack of effect of long-term supplementation with beta carotene on the incidence of malignant neoplasms and cardiovascular disease. N Engl J Med, 334, 1145-9.
Henvig, N., & Gro, C. H. (2005). Impact of socio-demographic factors, knowledog and attitude on the use of herbal drugs un pregnancy. Acta Obstet Gynecol Scand, 84, 26-33.
Huang,H.Y., Benjamin, C., Chang, S., Anthony, J. A., Richard, D. S., Christine, R. S., Renee, F. W., heng,T. Y., et al.( 2006). The Efficacy and Safety of Multivitamin and Mineral Supplement Use To Prevent Cancer and Chronic Disease in Adults: A Systematic Review for a National Institutes of Health State-of-the-Science Conference. Ann Intern Med, 145,372-385.
Isnard Bagnis, C., Deray, G., Baumelou, A., Le Quintrec, M., & Vabherweghem, J. L. (2004). Herbs and the Kidney. Am J Kidney Dis, 44, 1-11.
Izzo, A. A., Borrelli, F., & Capasso, R. (2002). Herbal medicine: the risk of drug interaction. Trends Pharmacol Sci, 23, 358-359.
Ishihara, J., Sobue, T., Yamamoto, S., Sasaki, S., Akabane, M.,& Tsugane,S., (2001). Validity and reproducibility of a self-administered questionnaire to determine dietary supplement users among Japanese. European Journal of Clinical Nutrition, 55, 360-365.
Jasti, S., Siega-Riz, A. M., & Bentley, M. E.,( 2003). Dietary supplement use in the context of health disparities: cultural, ethnic and demographic determinants of use. Journal of Nutrition, 133(6) , 2010-2013.
Jerrilynn, D. B., & Gloria, V. H.,( 2006). Herbs and Dietary Supplement Use in Patients with Stage 5 Chronic Kidney Disease. Nephrology Nursing Journal, 33.
Johnson, J. D., & Meischke, H. (1993). A comprehensive model of cancer-related information seeking applied to magazines. Human Communication Research, 19, 343-367.
Johnson, J. D., Meischke, H., Grau, J., & Johnson, S. (1992). Cancer-related channel selection. Health Communication, 18, 183-196.
Kaufman, D. W., Kelly, J. P., Rosenberg, L., Anderson, T. E., & Mitchell, A. A. (2002). Recent patterns of Medication Use in the Ambulatory Adult Population of the United States:The Slone Survey. JAMA., 287, 337-344.
Kelly, J. P., Kaufman, D. W., & Kelley, K. (2005). Recent trends in use of herbal and other natural products. Arch Int Med, 165, 281-286.
Kelly, L., Miller, M. D., Richard, S. L., Kristin Newby, L., & MHSb Durham, N. C. (2004). Complementary and alternative medicine in cardiovascular disease: A review of biologically based approaches. Am Heart J, 147, 401-411.
Kennedy, J. (2005). Herb and Supplement use in the US adult Population. Clinical Therapeutics, 27(11), 1847-1858.
Kephle, K., Wu, L. S., Yang, N. Y., & Lin, J. H. (2006). Herbal medicine research in Taiwan. Evid Based Complement Altemat Med, 3, 149-155.
Kessler, R. C., Davis, R. B., Foster, D. F., Van Rompay, M. I., Walters, E. E., & Wilkey, S. A. (2001). Long-term trends in the use of complementary and altermative medical therapies in the united States. Ann Intern Med., 135, 262-268.
Kivits, J. (2004). Researching the informed patient. Information Communication & Society, 7(4), 510-530.
Lam, A., & Bradley, G. (2006). Use of self-prescribed nonprescription medications and dietary supplements among assisted living facility residents. JAPhA, 46(5), 574-581.
Levy S. (2000). Mass-merchandisers pull ahead of drugstores in OTC sales. Drug Top 17-24.
Lew-Ting, C. Y. (2003). Who uses non-biomedical, complement and alternative health care? Sociodemographin undifferentiation and the effects of health needs. Taiwan Journal Public Health, 22(3), 155-166.
Lim, M. K., Sadarangani, P., Chan, H. L., & Heng, J. Y. (2005). Complementary and alternative medicine use in multiracial Singapore. Complementary Therapies in Medicine, 13(1), 16-24.
Lin, M. C., Nahin, R., Gershwin, M. E., Longhurst, J. C., & Wu, K. K. (2001). State of complementary and alternative medicine in cardiovascular, lung, and blood research【executive summary of a workshop】. Circulation, 103, 2038-2041.
Lucinda, G. M., (). Selected Clinical Considerations Focusing on Known or Potential Drug-Herb Interactions. Arch Intern Med, 158, 2200-2211.
MacLennan, A. H., Wilson, D. H., & Taylor, A. W. (2002). The escalating cost and prevalence of alternative medicine. Preventive Medicine 35(2), 166-173.
McNaughton, S. A., Mishra, G. D., Paul, A. A., Prynne, C. I., & Wadsworth, M. E. (2005). Supplement use is associatied with health status and health-related behaviors in the 1946 British birth cohort. J Nutr 135, 1782-1789.
Milden, S. P., & Stokols, D. (2004). "Physicians"attitudes and practices regarding complementary and alternative medicine. Behav Med, 30, 73-82.
Morrow, J. D., Edeki, T. I., EI Mouelhi, M., Galinsky, R. E., Kovelesky, R., Noveck, R. J., et al. (2005). American society for clinical Pharmacology and Therapeutics position statement on dietary supplement safety and regulation. Clin Pharmacol Ther, 77, 113-122.
Nicholas, P. K., & Hardiness. (1993). Self-care practices and perceived health status in older adults. Journal of Advanced Nursing, 18, 1085-1094.
Nordeng, H., & Havnen, G. C. (2005). Impact of socio-demographic factors, knowledge and attitude on the use of herbal drugs in pregnancy. Acta Obstet Gynecol Scand, 84, 26-33.
Patti, G., & Laura, S. M., (2008). Journal of the American Dietetic Association. Dietary supplements in the management of diabetes: potential risks and benefits. Journal of the American Dietetic Association, 108, 59-65.
Peng, C. C., Glassman, P. A., Trilli, L. E., Hayes-Hunter, J., & Good, C. B. (2005). Incidence and severity of potential drug-dietary supplement interactions in primary care patients: an exploratory study of 2 outpatient practices. Clin Pharmacol Ther, 77, 113-122.
Perkin, J. E., Wilson, W. J., Schuster, K., Rodriguez, J., & Allen-Chabot, A. (2002). Prevalence of nonvitamin, nonmineral supplement usage among university students. J. Am. Diet..Assoc, 102, 412-414.
Prentice, R. L., (2007). Clinical trials and observational studies to assess the chronic disease benefits and risks of multivitamin-multimineral supplements. American Journal of Clinical Nutrition, 85(1), 308-313.
Press, W. D. C. N. A. (1998). Dietary Reference Intake：Folate, other B vitamins and choline. Institute of Medicine.
Redelmeier, D. A., Tan, S. H., & Booth, G. L. (1998). The treatment of unrelated disorders in patients with chronic medical diseases. N Engl J Med. , 338, 1516-1520.
Richardson, A. (1991). Theories of self-care: Their relevance to chemotherapy-induced nausea and vomiting. Journal of Advanced Nursing, 16, 671-676.
Rock, C. L., (2007). Multivitamin-multimineral supplements: who uses them? Am J Clin Nutr(suppl), 85, 277-79.
Schäfer, T., Riehle, A., Wichmann, H. E., & Ring, J. (2002). Alternative medicine in allergies-prevalence, patterns of use, and costs. Allergy 57, 694 -700.
Schellevis, F. G., van der Velden, J., van de Lisdonk, E., van Eijk, J. T., & van Weel, C. (1993). Co-morbidity of chronic diseases in general practice. J Clin Epidemiol., 46, 469-473.
Singhal, S. G., & Goyle, R. A., (2001). Comparison of antioxidant efficacy of vitamin E, vitamin C, vitamin A and fruits in coronary heart disease: a controlled trial. Journal of the Association of Physicians of India, 49, 327-31.
Soeken, K. L., Miller, S. A., & Ernst, E., (2003). Herbal medicines for the treatment of rheumatoid arthritis: a systematic review. Rheumatology, 42, 652-659.
Steiger, N. J., & Lipson, J. G. (1985). Self- care Nursing: Theory and practice. Brady communications.
Stephanie, J. L., Evan, A. S., Henderson, I. C., Meir, J. S., William, C. W., Steven, R., Jan, R. D., Nicholas, J. R., & Walter, C. W., (1992). Carotenoids, retinol, and vitamin E and risk of proliferative benign breast disease and breast cancer. Cancer Causes and Control, 3, 503 - 512.
SY, A. S., Richard, M. B., & Diana, J. A., (2007). Herbal and Dietary Supplements for Treatment of Anxiety Disorders. Am Fam Physician, 76, 549-56.
Tindle, H. A., Davis, R. B., Phillips, R. S., & Eisenberg, D. M. (2005). Trends in use of complementary and alternative medicines by us adults：1997-2002. Alternative Therapies in Health and Medicine, 11(1), 42-49.
Ventura, M. T., Viola, M., Calogiuri, G., Gaeta, F., Pesole, O., & Romano, A. (2006). Hypersensitivity Reactions to Complementary and Alternative Medicine. . Current Pharmaceutical Design, 12, 3393-3399.
Weggemans, R. M., & Trautwein, E. A. (2003). Relation between soy-associated isoflavones and LDL and HDL cholesterol concentrations in humans :a meta-analysis. Eur J Clin Nutr, 57, 940-946.
Wheaton, A. G., Blanck, H. M., Gizice, Z., & Reyes, M. (2005). Medicinal herb use in a population-base survey of adults: prevalence and frequency of use, reasons for use, and use among their children. Ann Epidemiol, 15, 678-685.
Williamson, A., Fletcher, P., & Dawson, K. (2003). Complementary and alternative medicine, use in an older population. J Gerontol Nurs, 29, 20-28.
Gloria, Y. Y., Roger, B. D., & Russell, S., (2006). Use of Complementary Therapies in Patients With Cardiovascular Disease. Am J Cardiol, 98, 673- 680.
Yoon, S. L. (2006). Herbal, Prescribed, and Over-the-Counter Drug Use in Older Women: Prevalence of Drug Interactions. Geriatr Nurs, 27, 118-112.
行政院衛生署. (2006). 台灣地區死因統計結果 http://www.doh.gov.tw/statistic/data/衛生統計叢書2/95/上冊/index.htm
行政院衛生署網站. (2006). from http://www.doh.gov.tw/cht2006/index_populace.aspx
盧美秀. (1997). 第二十四章心臟功能失常病人之護理. 內外科護理學弟二冊‧台北：華杏.