近年來發現亞硝酸鹽/硝酸鹽型厭氧甲烷氧化菌，以甲烷作為脫硝反應的碳源及電子供給者，可同時除氮及減少溫室氣體甲烷的排放，因此本研究欲富集化N-DAMOs，針對不同植種污泥來源和馴養方式進行實驗，以釐清其表現行為及提供工程實務應用上之策略。
在批次式馴養發現高初始VSS濃度操作，有額外COD釋出問題，後續以半基質更換方式調降系統中微生物濃度，確實可改善甲烷利用狀況，其中又以MBR污泥為植種源，甲烷利用較為顯著，因此規劃另一組參數是MBR污泥當植種源並操作在低初始VSS濃度，發現N-DAMOs在系統中是優勢菌，且可得知初始VSS濃度是影響能否成功富集化N-DAMOs重要因素之一。
在厭氧流體化薄膜生物反應器實驗，亞硝/硝酸轉換率達82-100%，隨著亞硝/硝酸鹽氮負荷率提升，平均甲烷消耗速率及平均氮氣生成速率皆隨之增加。此外，連續流操作相較於批次式馴養，可獲得較高的亞硝/硝酸鹽氮轉換率達35.1 mg-N L-1 d-1。以反應槽污泥進行降解速率批次，初始亞硝/硝酸濃度為10-14 mg-N/L時，測得最高的比基質利用速率，然而若亞硝/硝酸同時存在，比基質利用率皆有下降之情形。在活性試驗，系統中有甲烷所獲得之亞硝酸鹽氮/硝酸鹽氮轉換速率皆相較於系統中無甲烷高，由此得知本研究兩個AFMBRs系統內皆具有N-DAMO菌群的活性。

In Fed-Batch culture, both of UASB and MBR sludge were used for inoculum, the NO2-/NO3- conversion would not be coupled to CH4 consumption under high VSS operation condition. After decreasing VSS by the dilution during nutrients exchange, CH4 decreased significantly with MBR sludge. It indicated that MBR sludge had the potential to enrich N-DAMOs. Moreover, VSS was one of the important factors to affect whether N-DAMOs’ enrichment was successful or not.
In AFMBR system, NO2-/NO3- conversion could achieve 82-100%. With the increase of NO2-/NO3- loading rate, average CH4 consumption rate and N2 production rate increased as well. Even though HRT decreased from 1.5 d to 1 d and 0.8 d, most of the NO2-/NO3- would be converted completely. Additionally, higher NO2-/NO3- loading rate could be obtained in AFMBR system comparing to Fed-Batch culture. Degradation batch experiments were performed by using biomass from two AFMBRs. The highest specific NO2-/NO3- conversion rate, specific CH4 consumption rate and specific N2 production rate achieved under initial NO2-/NO3- concentration was 10-14 mg-N/L. However, when adding NO2- and NO3- at the same time, all of the specific NO2-/NO3- conversion rate, specific CH4 consumption rate and specific N2 production rate decreased.
In batch test on N-DAMOs’ activity, NO2-/NO3- conversion rate obtained in experimental group (with methane in the system) was higher than in control group (without methane in the system). It indicated that N-DAMOs’ activity contributed in two AFMBRs. Also, this study was the first research using AFMBR to enrich N-DAMOs.

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