為了增強不鏽鋼於現今醫學儀器、用具使用上的性質，本研究是針對不鏽鋼表面做鍍膜的改質，以聚合物錯合溶液法製備氧化鋯(ZrO2)的前驅溶液，並以浸鍍法將此前驅溶液披覆於304不鏽鋼基材上，經乾燥熱處理後形成薄膜。
氧化鋯薄膜的微觀結構是以高解析場發射掃描式電子顯微鏡(Ultrahigh-Resolution Scanning Electron Microscopy) 觀測，結晶相是以低掠角X光繞射儀(Grazing incidence X-Ray Diffraction)檢測；其薄膜的表面化學鍵結是以電子光譜儀(Electron Spectroscopy for Chemical Analysis)量測，薄膜的厚度是以表面粗度儀(Alpha-Step Profilometer)量測，且以溶液黏度相互佐證；試片的表面粗糙度及顆粒型態是以AFM(Atomic force microscopy)觀察；生物相容性是以螢光染色分析、MTS及LDH的檢測結果表示之。
經熱處理至200 ℃~ 300 ℃所形成的氧化鋯薄膜為非結晶相，並且是由聚乙二醇(PEG)與鋯離子的錯合物所組成。試片經鍍上氧化鋯薄膜後能降低其粗糙度且提升其表面親水性。隨著前驅溶液黏度的增加，薄膜的厚度也隨之增加。體外測試結果顯示，含PEG之氧化鋯薄膜不但能達到與不銹鋼於現今醫療器材的使用標準，且有較佳的生物相容性，而PEG的添加量，以4.5 wt% 為最佳。

For the application of stainless steel in medical-related equipment, the properties of stainless steel (corrosion resistance, strength and wear resistance) should be enhanced. This study is aimed at the modification of the coating for the stainless steel surface. Zirconia (ZrO2) precursor solution was prepared by polymer complex solution method, and was dip coated on 304 stainless steel substrate to form thin film.
Microstructures and crystal phase of ZrO2 thin film were investigated by the SEM, XRD, and XPS. The thickness and corrosion resistances of ZrO2 thin film were analyzed by Alpha-Step profilometer and potentiodynamic polarization curve, respectively. Atomic force microscopy (AFM) was used to observe surface roughness and particle morphology. Biocompatibility was analyzed by immunocytochemistry, MTS, and LDH assay.
The zirconia thin film was amorphous when the temperature of heat treating was 200~300 ℃, and was composed by the polyethylene alcohol (PEG) with the zirconium ion complexes. The roughness and hydrophilic of stainless steel were improved by coating ZrO2 thin film. The ZrO2 thin films indeed increase the corrosion resistance of stainless steel and have good biocompatibility. The zirconia coatings sample had higher survival ratio and less cytotoxicity than stainless steel. The coating ZrO2 film sample could achieve medical objectives, and the best PEG contents were 4.5 wt%.

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