本論文主要利用薄膜式陽極氧化鋁(Anodic aluminum oxide, AAO)模板輔助電化學電鍍製備鎳金合金奈米柱，應用於非酶葡萄糖感測，與傳統鋁片式相比，薄膜式AAO解決了傳統鋁片式良率低的缺點，並縮短整體製程時間，同時使用低成本電鍍方式製備金鎳合金奈米柱，期望透過此種高表面積之結構，提升葡萄糖感測之靈敏度。
本實驗成功於P型重摻雜基板上製備鎳金合金奈米柱，在室溫下，配合調變酸鹼值至2.0、電鍍電壓(-1.6)V、電鍍週期10%等方式，利用脈衝式三極電鍍法得到最佳之鎳金合金奈米柱填孔均勻性，而後將模板完全移除，使得鎳金合金奈米柱完全裸露呈現筆直均勻分布，進一步進行葡萄糖感測。製備之鎳金合金奈米柱在進行連續葡萄糖及其他物質投入量測後，得到靈敏度1893(μAmM-1cm-2)、量測範圍0mM-3mM、感測極限1μM、選擇性佳及穩定度至少30天之葡萄糖感測器良好指標。

In this research, the fabrication of Ni-Au alloy nanowire for non-enzymatic glucose sensor on p-silicon based anodic aluminum oxide (AAO) template is discussed. The Ni-Au alloy nanowire is applied on an electrochemical glucose sensor.
The Ni-Au alloy nanowire was fabricated via the self-made AAO template grown on the p-type heavily doped silicon substrate. The advantages of AAO on silicon are lower cost, stronger mechanical and less production time consuming comparing to traditional AAO grown directly by using aluminum.
The electrodeposition of the Ni-Au alloy nanowire was fabricated by three-electrode system and pulse signals. The best parameter of Ni-Au alloy nanowire electrodeposition is (-1.6)V、PH2.0 and duty cycle 10%. To remove the AAO template after depositing, 2M alkaline medium was used in 30℃. The Ni-Au alloy nanowires exhibit high uniform arrangement. Further, use the Ni-Au alloy nanowires for the application of glucose measurement.
After a successive injection of glucose and other substantial for measurement, the Ni-Au alloy glucose sensor exhibited a linear range of 0-3mM, a sensitivity of 1893 μA/mMcm2, and a detection limit of 1μM. Simultaneously, a superior selectivity and at least 30 days stability was also observed. The characteristics show that Ni-Au alloy nanowire has an excellent performance for glucose sensing.

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