戴奧辛是目前環境中持久性有機污染物中最受矚目的污染物質，食物攝入為人體暴露戴奧辛/呋喃（PCDD/Fs）的主要途徑。研究顯示，臺灣環境中戴奧辛/呋喃主要來自煙道廢氣排放，經大氣擴散後沉降至植物及土壤中，經多介質分布轉移至食物鏈中。此意味著在排放源附近生長之動植物戴奧辛/呋喃含量可能較高。
因此本研究目的在於評估生活在戴奧辛類化合物排放源附近的人口之戴奧辛/呋喃攝食暴露量，探討當地自產食物是否為生活在排放源附近居民戴奧辛類化合物之重要暴露源。並從空氣中污染物濃度，建立模型預測環境及當地食物中的戴奧辛/呋喃含量。
本研究選擇了雲嘉南地區為研究區域，以花東地區為對照組。本研究結合大氣擴散模擬模式（ISCST3）及多介質評估模式之應用，依據美國國家環境保護署公告之人體健康風險評估草案（Human Health Risk Assessment Protocol, HHRAP）建立適用多介質模式，透過修正模式參數以有效且快速評估戴奧辛排放源附近當地自產農糧作物及禽畜品中戴奧辛/呋喃之含量。並進行民眾之暴露劑量評估。同時，本研究蒐集、彙整研究區域及對照區域之食品中PCDD/Fs實際測量含量。將各食品中戴奧辛/呋喃濃度配合國家攝食資料庫之攝食量數據及各年齡層體重等參數，推估臺灣各年齡層終生平均日暴露劑量（Lifetime Average Daily Dose, LADD）。
本研究挑選11個固定排放源作為大氣擴散模擬，經模擬後2016至2018雲嘉南空品區污染排放源附近區域之空氣中戴奧辛/呋喃濃度介於3.41×10-6 - 0.0478 pg I-TEQ/Nm3，符合日本所訂定之空氣品質標準0.6 pg-TEQ/Nm3。雲嘉南空品區污染排放源附近區域大氣中戴奧辛/呋喃總沈降量介於1.10×10-4 - 62.50 ng I-TEQ/m2-yr。利用ISC-ST3模擬大氣中戴奧辛/呋喃濃度及總沈降量結果顯示，台南市模擬值最高而雲林縣模擬值最低。空氣擴散模擬結果空氣中戴奧辛/呋喃最大毒性當量濃度點及最大著地濃度大多位於靠近排放源並位於農糧作物用地上，使污染排放源附近種植當地生長之農糧作物戴奧辛/呋喃濃度增加。
以多介質模式（Multimedia Model） 計算中各種食物中戴奧辛/呋喃之濃度，結果顯示PCDD/Fs總重毒性當量濃度平均值（pg I-TEQ/g）最高為雞蛋>牛肉>雞肉>穀物>豬肉>牛乳>地表作物>根莖類。在空間分布，以台南市>雲林縣>嘉義縣/市。在夏季根莖類作物、地表作物及穀物均呈現出較高濃度，其他季節平均值則較為相近。
本研究計算不同組別經飲食攝入戴奧辛之終生平均日暴露劑量（pg WHO05-TEQPCDD/Fs /kg BW/day），結果顯示研究組-實測為0.167 >研究組-模擬為0.142>對照組為0.107。其中研究組-實測與研究組-模擬暴露劑量接近，對照組之暴露劑量和其他兩組較低，可見地區之差別性。三個組別第95分位之終生平均日暴露劑量均符合世界衛生組織之每日容許劑量1～4 pg WHO05-TEQPCDD/Fs /kg BW/day，但研究組實測與模擬終生平均日暴露劑量分別有7.2%及5.8%超出歐洲食品安全局（EFSA）之每週容許劑量（TWI） 2 pg WHO05-TEQPCDD/Fs /kg BW/week建議值。根據敏感度分析結果，食物中戴奧辛/呋喃濃度和攝食量為影響風險之主要因子，因此對於有局部污染源之區域應強化飲食攝食管理，避免完全食用區域性食物或農作物，盡量分散飲食來源以降低暴露風險。

Human exposure to polychlorinated dibenzo-dioxins and -furans (PCDD/Fs), known as persistent organic pollutants, occurs mainly through the consumption of contaminated food. Because of the agricultural land not only wide but scrappy, it will highly cost manpower and economical resources by field survey in each place. This study is aimed to simulate the PCDD/Fs levels of foodstuffs nearby the PCDD/Fs emission sources using air dispersion model and to assess the contribution of those sources, to understand whether the local foods impacted by those PCDD/Fs emissions sources, finally to develop a Multimedia model to predict the PCDD/Fs contaminant levels in the local foods. Yun-Chia-Nan area was chosen as a study area in the present study, the PCDD/Fs emission data were applied to simulate ambient levels and deposition of PCDD/Fs by the industrial source complex short-term model (ISCST3). After using the multimedia model to simulate the PCDD/Fs levels of food, we found that PCDD/Fs concentrations (pg I-TEQ/kg) were listed from high to low as follows: eggs >beef >chicken >cereal >pork > milk > aboveground produce > root vegetables. Measured data on contamination levels in foodstuffs were collected from the reports of Taiwan Food and Drug Administration. The national food consumption database was considered for calculation of lifetime average daily dose (LADD) of PCDD/Fs in different age groups of Taiwan general population. The lifetime average daily dose (LADD) estimates expressed as pg WHO05-TEQPCDD/Fs /kg BW/day were 0.167 for study area (measured) > study area (modeling) for 0.142> 0.107 for reference area, respectively. The 95th percentile for all groups were below the Tolerable Daily Intake (TDI) value of 1～4 pg WHO05-TEQPCDD/Fs /kg BW/day suggested by WHO. Meanwhile, the tolerable weekly intake (TWI) (2 pg WHO05-TEQPCDD/Fs /kg BW/week) suggested by European Food Safety Authority (EFSA) is exceeded at the 95th percentile for two study groups. Although the estimation of LADD 95th percentile for all groups are below the TDI, which can be considered safe. It is still recommended. Emission sources-local foodstuffs is one of the exposure pathway to PCDD/Fs for residents living nearby the emission sources, and thus should not be neglected in developing future strategies and policies to protect the nearby inhabitants from PCDD/Fs exposure.

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