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研究生: 侯孟次
Hou, Meng-Tzu
論文名稱: 偏遠地區老年男性體適能與相關生化值之間相關性及其影響因子探討
Correlations and associated factors between physical fitness and serum biochemistry parameters in elderly male lived in rural area
指導教授: 官大紳
Kuan, Ta-Shen
共同指導教授: 吳至行
Wu, Chih-Hsing
學位類別: 碩士
Master
系所名稱: 醫學院 - 老年學研究所
Institute of Gerontology
論文出版年: 2011
畢業學年度: 99
語文別: 中文
論文頁數: 87
中文關鍵詞: 身體活動量髖骨骨密度空腹血糖值
外文關鍵詞: Physical activity, Hip bone mineral density, Glucose
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  • 本研究旨在了解偏遠地區老年男性的體適能現況及其與維他命D、血清生化值之間相關性,並考慮身體活動量、體脂率以及個人基本資料等因素加入討論為防治老化之參考。以高雄縣田寮鄉65歲以上男性共1033位為調查對象,於2010年七月間經全鄉篩檢選取414位完成檢測,回覆率達60.8%。每一位受測者完成基本資料問卷填寫外,並調查身體活動量、檢測髖骨密度(DXA, Hologic Explorer)及隔夜空腹血清檢查(25(OH)D、肌酸酐、腎絲球廓清率、血脂值等)。同時接受體適能檢測,包含身體質量指數、體脂率、慣用手握力(Grip-D, TKK 5401, Japan)、下肢肌力/肌耐力(5下坐站/30秒坐站測試)、平衡能力(開眼單足立)、下肢柔軟度(坐椅姿體前彎),以及反應能力(八呎來回走路時間)。經排除使用輔具與經診斷有嚴重的關節病痛之個案,總計402位資料完整之個案為最後分析對象,平均年齡為74.5±6.0歲。結果顯示,體適能隨著年齡增加而顯著下降,經分析結果發現三十秒坐站次數:年齡(-0.295)、體脂率(-0.136)、社經地位(0.101)、抽菸習慣(-0.219)、 身體活動量(0.178)、肌酸酐於1.5ng/ml為切點時(-0.099)和GFR-MDRDs在60 ml/min/1.73 m2 為切點時(0.106);開眼單足立:年齡(-0.386)、身體質量指數(-0.17)和空腹血糖值(-0.175);坐椅體前彎: 年齡(-0.169);八呎來回走路時間:年齡(0.322)、身體質量指數(0.156)、喝茶習慣(-0.122)、身體活動量(-0.22)和空腹血糖值(0.1);握力:年齡(-0.386)、身體質量指數(0.207)、身體活動量(0.144)和白蛋白(0.135)。維他命D及高密度脂蛋白膽固醇與體適能表現則無明顯相關性。 體適能隨著年齡增加而顯著下降,都市和鄉村的老年男性體適能常模宜有所不同。空腹血糖、肌酸酐與腎絲球廓清率與老年體適能狀態有關,將可作為臨床篩檢與評估老年身體功能狀態之參考。

    The purpose of this study was to disclose the relationship between serum biochemistry parameters and physical fitness performance in old male lived in rural community in Taiwan.
    We used 1033 men aged 65 and over lived in Tianliao District, Southern Taiwan was selected in an epidemiological survey in July 2010. A total of 414 subjects were enrolled, the respond rate was 60.8%. Not only structured questionnaires were inquired by face-to-face instructor for each subject, but also physical activity of weekly, hip bone mineral density and serum biochemistry parameters: vitamin D, creatinine, GFR-CG, GFR-MDRDs and HDLC were collected. The physical fitness tests had grasp test of dominant hand (grip-D, TKK 5401, Japan), muscle strength/endurance (30-s chair stand test), balance (open-eye stand on right foot), flexibility (chair sit-and-reach test), and reaction(8-feet walking test). There were 402 subjects completed the study, the average age was 74.5±6.0 (range=65-98) y/o. Using multiple linear regression models, the independent factors (β coefficient) for different physical function tests were listed as followings: 30-s chair stand test =age(-0.295), percent body fat(-0.136), socioeconomic state(0.101), smoking(-0.219), physical activity(0.178), creatinine with 1.5ng/ml cut point(-0.099) and GFR-MDRDs with 60 ml/min/1.73 m2 cut point(0.106); open-eye stand: age(-0.386), BMI(-0.17) and glucose(-0.175); chair sit-and-reach test: age(-0.169); 8-feet walking test: age(0.322), BMI(0.156), tea(-0.122), physical activity(-0.22) and glucose(0.1); hand grip test: age(-0.386), BMI(0.207), physical activity(0.144), Albumin(0.135). Vitamin and HDLC didn’t have correlation with any physical fitness performance significantly. We can use creatinine and GFR-MDRDs to predict the muscle strength and endurance of elderly, and glucose may use to predict balance and reaction ability of elderly. These results will provide the general status of physical functions and the value of indicators to show intercorrelated with serum biochemistry data.

    誌謝 I 中文摘要 II 英文摘要 III 目錄 IV 第一章、緒論 1 第一節:人口背景資料 1 第二節:老化與身體功能及生化指標 2 第三節:研究目的 7 第二章、文獻回顧 8 第一節:維他命D與身體功能表現 8 一、 生理機制 8 二、 生化值異常 9 三、 生理功能影響 10 第二節:腎絲球廓清率相關生化值與身體功能表現 15 一、 生理機制 15 二、 生化值異常 15 三、 生理功能影響 16 第三節:血脂與身體功能表現 20 一、 生理機制 20 二、 生理功能影響 21 第三章:研究方法 23 第一節:研究設計與架構 23 第二節:研究地點、對象和抽樣 24 一、 研究地點 24 二、 研究對象 25 第三節:研究流程 27 一、 事前準備 27 二、 檢查過程 27 三、 事後報告結果與資料處理 28 第四節:研究工具 29 第五節:名詞解釋 35 第六節:統計分析 36 第四章:研究結果 37 第一節、受測者基本資料與描述性統計 37 第二節、與體適能相關因子之單變項分析 41 第三節、體適能相關之多變項分析 49 第五章:討論 52 第一節、體適能表現之現況與比較 52 一、 田寮鄉老年男性體適能現況 52 二、 體適能表現比較 53 第二節、體適能表現與血清生化值 56 一、 維他命D 56 二、 肌酸酐、GFR-CG與GFR-MDRDS 57 三、 高密度脂蛋白膽固醇 59 四、 空腹血糖 60 五、 白蛋白(ablumin) 62 第六章:結論與建議 63 第七章:參考文獻66

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