在實驗室晶片 (Lab-On-a-Chip) 應用中一項重要的功能是如何將流體在微小型之裝置上進行快速且均勻的微尺度混合 (Micromixing)，這對於在生物醫學和化學檢測等領域上具有實質的效益。目前主動式人工纖毛 (Artificial cilia) 微混合器被視為非常有效促進分子擴散效率的機制，透過人工纖毛的擺動將欲混合的流體進行不斷地拉伸與重疊，達到在短時間內均勻混合的效果，因此非常適合應用在極端的流場條件 (例如具有高黏性的流體)。然而，截至目前為止扔然沒有一套人工纖毛擺動標準範例的提出，說明如何達到最佳的混合效率。因此本研究根據流體動力學之概念，設計出幾種代表性的人工纖毛擺動模式，來描述人工纖毛擺動與週圍引起的流場效應之間的交互關係，並藉由微粒子影像測速儀 (Micro particle image velocimetry, µPIV) 的量測來獲得瞬時流場分佈。當人工纖毛的擺動模式同時滿足本研究所提出的三種條件時，其混合效率可在6秒鐘內上升44%。對於未來新設計的微混合器提供一個有效的設計依據，以促進實驗室晶片商品化的推動，縮短檢測的時程。

In the lab-on-a-chip application, it has been always an important aspect to miniaturize the micromixing device to attune uniform and rapid micro mixing. Active micromixing technology possesses significant interest among the researchers, as uniform mixing can be achieved in a shorter period of time through compensating a very considerable amount of external energy. In microscale, fluid mixing through the actuation of artificial cilia has been found to be very effective. However, no standard artificial cilia beating protocols existed till date, through which best mixing performance can be achieved. Therefore, this study is specifically designed to understand the hydrodynamic behavior of several artificial cilia beating patterns and to clarify the interactions between the flow field and the artificial cilia beating within. The instantaneous flow field has been studied through micro particle image velocimetry measurement technique. Through this study, it was aimed to provide an artificial cilia based micromixer by which an efficient micromixing can be achieved in a shorter period of time.

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