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研究生: 陳奐妤
Chen, Huan-Yu
論文名稱: 醫院別手術死亡率排序之方法學問題探討
Ranking Hospitals According to Surgical Mortality: An Analysis of Methodological Issues
指導教授: 呂宗學
Lu, Tsung-Hsueh
學位類別: 碩士
Master
系所名稱: 醫學院 - 公共衛生學系
Department of Public Health
論文出版年: 2014
畢業學年度: 102
語文別: 中文
論文頁數: 83
中文關鍵詞: 健康照護品質手術處置醫院死亡術後併發症搶救不力
外文關鍵詞: Quality of Health Care, Surgical Procedures, Hospital Mortality, Postoperative Complications, Failure-to-Rescue
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  • 背景:不少醫院別醫療照護品質評比機構使用手術死亡率作為醫療照護品質指標,但是也引起許多方法學爭議。有學者提出「搶救不力」(failure to rescue)指標(分母是手術發生併發症個案數,分子是這些個案死亡數)比較能反映照護團隊的經驗與照護能力,也就是及早發現併發症(譬如手術後出血或感染或是栓塞),及早啟動搶救措施避免死亡發生。
    目標:本研究使用病患風險調整死亡率的醫院別排序當金字標準,首先與使用粗死亡率與年齡標準化死亡率醫院別排序比較是否有差異;二是與使用粗併發症發生率、年齡標準化併發症發生率與病患風險調整併發症發生率醫院別排序比較是否有差異;三是與使用粗搶救不力率、年齡標準化搶救不力率與病患風險調整搶救不力率醫院別排序比較是否有差異。最後嘗試同時使用三種指標及群組化三分位方式來排序醫院,檢視是否能提供較佳標竿學習訊息。
    材料與方法:本研究使用2000-2010年全民健保申報住院醫療費用清單明細檔比較醫院別執行冠狀動脈繞道術(CABG)與經皮冠狀動脈擴張術(PTCA)兩處置之死亡率、併發症發生率與搶救不力率排序差異。這三個率也都分別比較病患病患風險調整率、年齡標準化率與粗率排序之差異。不同指標醫院別排序之相關使用斯皮爾曼等級係數檢定。
    結果:在研究期間執行CABG一百例以上的醫院有41間,執行PTCA二百例以上的醫院有84間。以年齡標準化死亡率進行醫院別排序的結果與以病患病患風險調整死亡率醫院別排序結果(金字標準)的相關係數:CABG為.99,PTCA為.98。若以粗死亡率進行醫院別排序,與金字標準的相關係數下降為:CABG為.98,PTCA.93。病患病患風險調整併發症發生率與病患病患風險調整死亡率的的相關係數:CABG為.62,PTCA為.63。病患病患風險調整搶救不力率與病患病患風險調整死亡率的的相關係數:CABG為.80,PTCA為.87。如果同時以三個指標區分高中低三分位,執行CABG醫院可區分為十四組,PTCA可區分為十八組,可以提供較細膩的標竿學習討論。
    結論:本研究顯示搶救不力率與病患病患風險調整率的相關係數沒有預期高,最主要理由是本研究的病患病患風險調整率只是用健保申報資料的共病症進行調整,缺乏病患嚴重度資料(譬如冠狀動脈阻塞程度與心臟功能相關數據),所以不見得是很好的金字標準。未來還是應該透過病歷資料分析確認搶救不力的價值。不過,同時呈現三種指標的群組化分組來排序,應該可以提供比較多元資料提供標竿學習參考。

    Background: Ranking hospital quality of care according to surgical mortality had many debates. Silber proposed “failure-to-rescue”, the mortality rate among surgical patients with complications, as an emerging quality indicator.
    Objectives: The objective of this study was to assess the correlation among hospital quality assessment ranking based on crude/ age-adjusted/ risk-adjusted mortality, complication and failure-to-rescue rate. We then assessed the ranking hospitals by combining three indicators and using aggregated information to provide better benchmark learning.
    Materials and methods: This study use inpatient claims data set to compare hospital outcome rankings for three different measure of quality of care: hospital death, complication and failure-to-rescue.
    Results: For 41 hospitals of CABG and 84 hospitals of PTCA, the correlation between hospital rankings based on age-adjusted mortality rate and patient-risk-adjusted mortality rate were high correlations (CABG, r=.99; PTCA, r=.98). A similarly high correlation was present between the patient-risk-adjusted mortality and FTR rate (CABG, r=.80; PTCA, r=.87). There were moderate correlations between patient-risk-adjusted complication and mortality (CABG, r=.62; PTCA, r=.63).
    Conclusions: The findings of this study indicate that the correlation between failure-to-rescue and patient-risk-adjusted mortality rate was not as high as expected. One of the possible explanations was that many severity of illness information were not available in claims data. Studies using medical record to verify the validity of failure-to-rescue concept are needed. However, the classification of hospitals according to combined information could provide useful information for benchmark learning.

    第一章 緒論 1 第一節 研究背景與動機 1 第二節 研究目的 3 第三節 預期貢獻 4 第二章 文獻回顧 5 第一節 手術死亡率作為醫療品質指標 5 第二節 醫院別手術死亡率比較之方法學問題 14 第三節 併發症發生率及搶救不力率兩種指標之提出 18 第四節 文獻回顧小結 26 第三章 材料與方法 28 第一節 研究材料 28 第二節 研究變項與測量 28 第三節 資料分析 30 第四章 研究結果 32 第一節 基本資料 32 第二節 個別醫院不同指標之排序 33 第三節 死亡率醫院別排序之相關 34 第四節 病患風險調整死亡率與併發症及搶救不力之排序相關性 34 第五節 綜合三個指標群組化排序 35 第五章 討論 37 第一節 本研究主要的結果與解釋 37 第二節 研究發現可能的解釋 38 第三節 與過去研究之比較 41 第四節 研究限制與未來方向 42 參考文獻 46 附錄一:2000-2010年接受 CABG患者之個人特徵與三種粗率 75 附錄二:2000-2010年接受 CABG患者之個人特徵與三種率之勝算比 78 附錄三:2000-2010年接受 PTCA患者之個人特徵與三種粗率 79 附錄四:2000-2010年接受 PTCA患者之個人特徵與三種率之勝算比 82 附錄五:Dartmouth-Manitoba's CCI(D-M's CCI) 83 表目錄 表一:台灣執行CABG醫院基本資料 50 表二:台灣執行PTCA醫院基本資料 51 表三:台灣執行CABG醫院三個指標粗率 52 表四:台灣執行CABG醫院三個指標調整率 53 表五:台灣執行PTCA醫院三個指標粗率 54 表六:台灣執行PTCA醫院三個指標調整率55 表七:2000-2010年台灣執行CABG一百例以上醫院 56 表八:2000-2010年台灣執行PTCA二百例以上醫院 59 表八:2000-2010年台灣執行PTCA二百例以上醫院 64 表九:2000-2010年台灣執行CABG一百例以上醫院與執行PTCA二百例以上醫院病患風險調整(R)、年齡調整(A)與粗(C)死亡率排序斯皮爾曼等級係數 65 表十:2000-2010年台灣執行CABG一百例以上醫院與執行PTCA二百例以上醫院病患風險調整(R)、年齡調整(A)與粗(C)併發症發生率與搶救不力率與病患風險調整死亡率排序斯皮爾曼等級係數 66 表十一:2000-2010年台灣執行CABG一百例以上醫院依照病患風險調整死亡率、併發勝發生率與搶救不力率分組及醫院層級別統計 67 表十二:2000-2010年台灣執行PTCA二百例以上醫院依照病患風險調整死亡率、併發勝發生率與搶救不力率分組及醫院層級別統計 68 圖目錄 圖一:2000-2010年台灣執行CABG一百例以上醫院病患風險調整死亡率與年齡調整死亡率與粗死亡率排序之散佈圖 69 圖二:2000-2010年台灣執行PTCA二百例以上醫院病患風險調整死亡率與年齡調整死亡率與粗死亡率排序之散佈圖 70 圖三:2000-2010年台灣執行CABG一百例以上醫院病患風險調整死亡率與病患風險調整併發症發生率排序之散佈圖 71 圖四:2000-2010年台灣執行CABG一百例以上醫院病患風險調整死亡率與病患風險調整搶救不力率排序之散佈圖 72 圖五:2000-2010年台灣執行PTCA二百例以上醫院病患風險調整死亡率與病患風險調整併發症發生率排序之散佈圖 73 圖六:2000-2010年台灣執行PTCA二百例以上醫院病患風險調整死亡率與病患風險調整搶救不力率排序之散佈圖 74

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