乳癌在近幾年已經成為台灣地區女性主要的死亡原因，因此，乳癌的早期診斷以及治療已經成為一個重要的課題。故我們希望找到快速偵測乳房組織參數的方法。在生醫組織光學中，漫反射光譜系統(DRS)可以透過快速且非侵入式的方式量化體內組織的成分，DRS可以測量組織假體在近紅外光波段下的吸收係數和散射係數。
　　因此，本文主要為利用DRS的光學方法獲得液態假體光譜並且分析其參數。首先會利用DRS量測液態假體在500nm~1000nm波段的反射光譜圖，最後，利用多距離演算法和多波長演算法，對光譜圖進行反算並且比較兩種演算法所得到的吸收係數和散射係數。液態假體所選擇的吸收係數和散射係數範圍為正常乳房組織和病變乳房組織，其目的為希望未來可以發展出一套非侵入式且簡單亦便宜的系統，以便未來可以量測乳房並定量組成濃度。
　　研究結果為多距離演算法和多波長演算法所得到的光學參數並沒有太大之差異，皆可以透過這兩種演算法得到光學參數，且未來亦可以用多波長演算法量測非均質組織的情況淺層腫瘤組織所造成的光學性質變化。

In this thesis, we demonstrate the use of optical method, diffuse reflectance spectroscpoy (DRS), and we will the obtain spectrum of liquid phantoms from DRS, to investigate physiological parameters of liquid phantoms. First, we will obtain reflectance of phantoms at the range of 500nm to 1000nm. Further we will compare two spectral fitting methods of DRS in measuring biological optical properties, one is Multi-Wavelength method and another is Multi-Distance method. The liquid phantoms are used to measure the absorption and scattering coefficient under the range of normal and tumorous breast tissue by these two spectral fitting methods, and to compare both effect. The purpose is to construct a non-invasive, cheaper and simple optical system, and the system can quantify the chromophore concentrations of breast tissue in the future.

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