玉米因其高能量含量與良好消化率而成為畜禽飼料的重要組成部分，但極易受到鎌刀菌（Fusarium）污染，並產生如脫氧雪腐鎌刀菌烯醇（Deoxynivalenol, DON）與玉米赤黴烯酮（Zearalenone, ZEA）等黴菌毒素。此類毒素不僅威脅動物健康，亦危及食品安全；而傳統去毒方法往往降解效率有限，或可能留下有害殘留物，因此亟需創新、非熱處理之替代技術。本研究旨在評估冷大氣壓電漿（Cold Atmospheric Plasma, CAP），由大氣壓電漿射流（Atmospheric Pressure Plasma Jet, APPJ）所產生，在降解 DON 與 ZEA 方面之效能。實驗採用兩種模式：其一為於反滲透（RO）水中添加標準黴菌毒素溶液；其二為人工污染之玉米飼料樣品。CAP 的處理條件涵蓋不同處理時間（2、4、6、8 與 10 分鐘）、放電頻率（15、20 與 30 kHz）以及功率水平（400、420 與 450 W）。黴菌毒素濃度透過經驗證之 UPLC-MS/MS 方法進行檢測，以確保數據之準確性與可靠性。研究結果顯示，CAP 在水相體系中對兩種黴菌毒素均具有顯著降解效果，其中 DON 的最大降解率約為 94%，ZEA 可達 100%。在玉米飼料體系中，DON 的最大降解率為 54%，ZEA 為 40%，且降解效率隨處理時間延長而提高，顯示電漿產生之活性物種在降解過程中具有關鍵作用。綜合而言，本研究結果指出，CAP 作為一種無化學添加之新興技術，在降低飼料中黴菌毒素污染、提升飼料安全性，以及減少食物鏈中毒素暴露風險方面，展現出良好應用前景。

Maize is a key component of livestock feed due to its high energy content and digestibility but is highly susceptible to Fusarium contamination, which produces mycotoxins such as Deoxynivalenol and Zearalenone. These toxins threaten animal health and food safety, while conventional decontamination methods often show limited efficacy or leave toxic residues. highlighting the need for innovative, non-thermal alternatives. This study evaluated the effectiveness of cold atmospheric plasma, generated using an atmospheric pressure plasma jet, for degrading Deoxynivalenol and Zearalenone in both aqueous solution and maize-based animal feed. Two experimental models were employed: RO water spiked with mycotoxins, and artificially contaminated maize feed. CAP treatment parameters included varying durations (2, 4, 6, 8, and 10 minutes), discharge frequencies (15, 20, and 30 kHz), and power levels (400, 420, and 450 W). Mycotoxin concentrations were quantified using a validated UPLC-MS/MS method, ensuring accurate and reliable detection. The results demonstrated that CAP achieved substantial degradation of both mycotoxins in RO water, with maximum reduction rates of approximately 94% for Deoxynivalenol and 100% for Zearalenone. In maize-based feed, the maximum degradation reached 54% for DON and 40% for ZEA, depending on the treatment conditions. The degradation efficiency increased with longer treatment time, indicating the crucial role of plasma-generated reactive species. These findings suggest that CAP is a promising, non-chemical approach for reducing mycotoxin contamination in animal feed, offering a practical solution to enhance feed safety and reduce mycotoxin exposure risks in the food chain.

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