微型全分析系統(Micro Total Analysis Systems, mTAS)已經在單一晶片上發展出包含化學反應、分離和感測的多種分析程序，由於其針對生物化學分析的微小化與整合的特性，在近年來已經有相當大的進展。
在微小化系統的整合中，微流體處理技術，例如：微流體輸送、計量與混合，為一相當重要的課題。對微流體系統而言，必須達成快速且有效的混合。微流體混合器的設計，除了考慮整合性，同時也要達到迅速混合的目的。本論文採用在主流道中置入數個J型阻塊的方式設計一新型被動式微混合器，並利用數值模擬與實驗探討此微混合器。而其平面式結構的製作方法是使用SU-8厚膜光阻來當作母模，並以PDMS為材料的微型模造技術。微流道測試實驗是在顯微鏡下拍攝流體的混合情形，運用影像分析軟體量測濃度分佈情形，經過測試的結果顯示，在雷諾數Re=5～50.1和Re=71.6～358，有J型阻塊的流道結構混合效果優於典型T型流道結構，主流道中的J型阻塊能產生側向對流效應，因此而改善了混合的效果。

Micro Total Analysis Systems (mTAS) have been developed to undergo a number of analytical processes involving chemical reactions, separation and sensing all performed on a single chip. The mTAS research, which is aimed at biochemical analysis miniaturization and integration, has recently made dramatic progress.
An important issue for this integration is microfluid management technique, i.e. microfluidic transportation, metering, and mixing. Effective mixing is essential to many of the microfluidic systems. The present work proposed a novel design of the passive micromixer which employed several J-shaped blocks in the main channel to enhance mixing. Both numerical and experimental investigations have been achieved in this study. The in-plane structured micromixer was fabricated using the micromolding of SU-8 photoresist and made of PDMS. The mixing performance has been demonstrated employing the image analyzing software to quantity the concentration distribution in the microchannel. The mixing efficiency of the micromixers with J-shaped blocks is better than that of the traditional T-shape mixer at Re= 5 to 50.1 and 71.6 to 358 according to the experimental results. The results reveal that the J-shaped blocks can cause the lateral convection in the main channel; therefore the mixing has been improved.

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