| 研究生: |
沈智民 Shen, Chih-Min |
|---|---|
| 論文名稱: |
台灣馬桑莖部成分之研究 The constituents of the stems of Coriaria intermedia Matsum. |
| 指導教授: |
吳天賞
Wu, Tian-Shung |
| 學位類別: |
碩士 Master |
| 系所名稱: |
理學院 - 化學系 Department of Chemistry |
| 論文出版年: | 2009 |
| 畢業學年度: | 97 |
| 語文別: | 中文 |
| 論文頁數: | 147 |
| 中文關鍵詞: | 台灣馬桑 、馬桑內酯 |
| 外文關鍵詞: | coriaria intermedia, coriaria lactone |
| 相關次數: | 點閱:26 下載:1 |
| 分享至: |
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由台灣馬桑(Coriaria intermedia Matsum.)之莖部分離得到46個合物,其中44個化合物經由光譜分析,確定其化學結構,分別為braylin、toddanin、7-hydroxycoumarin、angustifolin、scopoletin、coriarintin A、coriarintin B、coriarintin C、coriarintin D、coriarintin E、demethylramosinin、7-hydroxy-3,8-bis(3-methyl-2-butenyl) coumarin、corianin、tutin、coriamyrtin、corinterin A、methyl gallate、gallic acid、ellagic acid、3,4'-O-dimethylellagic acid、3,3'-O-dimethylellagic acid、3,3'-O-dimethylellagic acid-4'-O--glucopyranoside、3,3'-O-dimethylellagic acid-4'-O--xylopyranoside、methyl 2-(4-hydroxyphenyl) acetate、tetracosyl (E)-ferulate、coriamedin A、coriamedin B、-sitosterol、stigmasterol、ergosta-7,22-dien-3-ol、-sitosteryl 3-O--D-glucopyranoside、(24R)-24-ethylcholesta-4,22-dien-3-one、ursolic acid、oleanolic acid、20-epibryonolic acid、5-hydroxymethyl-2-furanocarboxaldehyde、coriamedin C、succinic acid monobutyl ester、(R)-dimethylmalate、2,6-dimethoxybenzoquinone、squalene、brevifolin、glyceryl-1-tetracosanoate。其中coriarintin A、coriarintin B、coriarintin C、coriarintin D、coriarintin E、corinterin A、corinterin B、coriamedin A、coriamedin B和coriamedin C為首次發現的新化合物。demethylramosinin以及7-hydroxy-3,8-bis(3-methyl-2-butenyl) coumarin為天然界首次分離得到的新化合物。上述化合物的結構乃是利用核磁共振光譜、質譜、紫外光譜以及紅外光譜藉以決定,而已知的化合物則是與文獻所報導的物理性質和光譜數據進行比對得到確認。
Phytochemical investigation of the methanol extract of the stems of Coriaria intermedia Matsum. afforded forty-six compounds. Among them, forty-four were identified as braylin, toddanin, 7-hydroxycoumarin, angustifolin, scopoletin, coriarintin A, coriarintin B, coriarintin C, coriarintin D, coriarintin E, demethylramosinin, 7-hydroxy-3,8-bis(3-methyl-2-butenyl) coumarin, corianin, tutin, coriamyrtin, corinterin A, methyl gallate, gallic acid, ellagic acid, 3,4'-O-dimethylellagic acid, 3,3'-O-dimethylellagic acid, 3,3'-O-dimethylellagic acid-4'-O--glucopyranoside, 3,3'-O-dimethylellagic acid-4'-O--xylopyranoside, methyl 2-(4-hydroxyphenyl) acetate, tetracosyl (E)-ferulate, coriamedin A, coriamedin B, -sitosterol, stigmasterol, ergosta-7,22-dien-3-ol, -sitosteryl 3-O--D-glucopyranoside, (24R)-24-ethylcholesta-4,22-dien-3-one, ursolic acid, oleanolic acid, 20-epibryonolic acid, 5-hydroxymethyl-2-furanocarboxaldehyde, coriamedin C, succinic acid monobutyl ester, (R)-dimethylmalate, 2,6-dimethoxybenzoquinone, squalene, brevifolin, glyceryl-1-tetracosanoate. Among them, ten compounds neamed coriarintin A, coriarintin B, coriarintin C, coriarintin D, coriarintin E, corinterin A, corinterin B, coriamedin A, coriamedin B and coriamedin C were new compounds. Demethylramosinin and 7-hydroxy-3,8-bis(3-methyl-2-butenyl) coumarin were reported for the first time from the natural sources. Their structures were determined by 1H, 13C, 2D NMR, MS, UV-Vis and IR spectral analyses. The known compounds were identified by comparison of their physical and spectral data with those reported in the literature.
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