背景：男性間性行為者是感染愛滋病毒的高危險群之一。男同性戀三溫暖是一男男性接觸的主要場所。2009年，衛生福利部疾病管制署(前台灣衛生署疾病管制局)為了愛滋防治的目的資助非政府組織建立了同志健康中心提供男性間性行為者，不同於三溫暖的社交場域。此外近年來隨著網際網路的興起，也分散了男同性戀三溫暖的使用者。本研究的目的是(1)比較各場域愛滋病毒和性傳染疾病感染的盛行率，以及(2)不同場域男性間性行為者感染愛滋病毒與其他性傳染疾病的危險因子，以提供有關單位未來訂定政策的參考。
方法：本研究為橫斷面研究(Cross-sectional study)，依台灣男性間性行為者尋找性伴侶的場域進行分組，使用半自填結構問卷進行資料收集，問卷內容包括：基本人口學資料、藥物使用、過去性史、保險套使用等部分。這些人皆以匿名收集以其血液和尿液檢體送國立成功大學醫學院附設醫院及國立臺灣大學醫學院附設醫院檢驗分析其愛滋病毒及性傳染疾病狀況。
結果：本研究資料收集期間由2009年3月至2012年11月共回收問卷2416份。性傳染疾病盛行率在男同性戀三溫暖是愛滋病毒6.7％，梅毒20.4％，B型肝炎13.1％，阿米巴8.8％；在同志健康中心是愛滋病毒2.9％，梅毒9.9％，B型肝炎8.9％，阿米巴1.4％。同志健康中心（24.0％）和男同志三溫暖（16.1％）有使用娛樂性藥物經驗。
結論：不同場域其性病盛行率及性行為模式不同，男同志三溫暖的疾病盛行率仍為最高。使用安非他命是年輕男性間性行為者一個嚴重的健康問題。提供全面的預防服務可以減少男性間性行為者降低感染風險。研究發現強調了需要在不同地點為男男性接觸者更全面的愛滋病防治工作。

Introduction
Men who have sex with men (MSM) are the primary risk group for HIV infection. Gay sauna is a primary venue for MSM. In 2009, Taiwan CDC financially supported NGO established Gay Centers to build up a social venue for MSM. The purposes of the study are to compare the prevalence of HIV ,sexually transmitted infections (STIs) and risk behaviors among MSM using voluntary HIV counseling and testing services (VCT) in the venues, in order to evaluate the policy and formulate health education strategies in the future.
Methods
Using cross-sectional study samples, we compared 2416 MSM who used voluntary counseling and testing (VCT) during 2009 to 2012. After obtaining permission from venues owners, patrons were approached by trained male volunteers when they checked into the bathhouse and invited to participate in the study. Patrons who agreed to participate were asked if they have been participated in the project before. Trained male volunteers explained to participants about the items of HIV/STI screening listed on the consent form and helped them to complete a one-page self-administered questionnaire. The study protocol included providing HIV/STI information and counseling, free and anonymous HIV/STI tests: serological tests for HIV, syphilis and Amoebiasis. Logistic regression identified factors associated with unprotected anal intercourse (UAI) at their most recent venue visit. SPSS 14.0 for Windows (SPSS, Chicago, IL, USA) was used for all statistical analyses. To test for trends of HIV and STIs over time, we used χ2 tests for linear trends that considered the year of the survey as an ordered categorical variable. We used χ2 tests to evaluate the association between the positive and reactive results of each HIV and STI and various correlates: demographic characteristics, illicit drug usage, and risky sexual behaviors. Continuous variables were analyzed using t tests or analysis of variance (ANOVA). Logistic regression was used to examine the statistical relationships between the primary independent variable (HIV/STIs and consistent condom use in anal intercourse in bathhouses) and significant correlates selected from univariate analysis, while controlling for age. The proposed correlates were entered into the regression model hierarchically, with the presence of STIs entered first, prior risky behavior entered second, condom-use behavior entered third, and individual characteristics entered last. The final models achieved goodness-of-fit as assessed using the Hosmer–Lemeshow goodness-of-fit test. Statistical significance was set at P < 0.05.

Result
The HIV/STIs prevalence rate in gay sauna was 6.7% for HIV infection, 20.4% syphilis, 13.1% HBV, 1.7%, 8.8% Amoebiasis. In LGBT Center was 2.9% for HIV infection, 9.9% syphilis, 8.9% HBV, 1.4% Amoebiasis. The percentage of using recreational drugs among MSM enrolled in LGBT Center (24.0%) is significant higher than MSM in Gay sauna (16.1%).
Conclusions
The HIV/STI prevalence and risky behaviors of MSM enrolled in venues are different. Meth-amphetamine using is a serious health issue for young MSM. Comprehensive prevention services provided within venue may reduce undiagnosed HIV infection among MSM. These findings highlight the need for more comprehensive HIV prevention efforts for MSM in different venue.

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