複合樹脂材料經長時間的開發至今，在材料本身的物理化學性質、力學強度、可塑性、操作性以及長期耐用度上，已有相當程度的提升。除此之外，透過調整黏著劑成分和改善黏著機制，複合樹脂在與牙釉質及牙本質接著時，都可提供不錯的黏著強度。因此，有學者提出應用牙科用複合樹脂配合深度邊緣提升術(Deep Margin Elevation)，來解決齒齦下深度邊緣的問題，以取代傳統的牙冠增長術。
由過去文獻中可發現，對於嵌體和蓋體等非直接式牙科補綴物的設計都僅就少數幾個設計參數或設計點個別討論，而沒有大規模系統性的研究。而關於深度邊緣提高術的研究亦多侷限在填補後邊緣完整性的探討，並無深入探討其使用之補綴物設計及材料選擇，復形後之力學行為及長期耐用性也未有完整的討論。
本研究首先將建立一三維人類小臼齒有限元素模型，進行第二類窩洞嵌體幾何設計之參數化研究，探討各項設計參數對牙齒及補綴物之力學行為的影響力；再以反應曲面模型來預測不同設計下，牙齒與補綴物之力學行為與交互關係。並使用此模型來建立一個具有力學基礎之設計建議，提供臨床醫師進行此類補綴物設計時，在調整嵌體設計參數上作為參考來降低牙齒或補綴物發生脫離或斷裂的情況。
本研究結果顯示，透過調整設計參數，可在一定程度上改善牙齒結構內以及材料結合面上的拉伸應力分布情形，且不同的嵌體材料對於設計參數的需求不盡相同。而使用DME於具有深度邊緣的第二類窩洞嵌體補綴中，對於牙齒的力學行為並無明顯的影響。

The proposed study is aimed to evaluate the mechanical performance of various design parameters of inlay for cavities with deep margin elevation and the inter-relationship among these parameters. Finite element analysis was introduced to simulate the mechanical behaviour of the tooth and restoration. Response surface method was used to analysis the relationship between the mechanical performance of restored tooth and different prosthetic designs. Three materials of inlay: composite resin, ceramics, and glass-ceramic were examined in the present study. The result shows for all three materials, a wide isthmus will benefit the mechanical strength of the restored tooth. The effects of other parameters on the tooth’s mechanical behaviour varied when different material of inlay was used, but the thickness of the elevation didn’t show a strong influence. For conclusion, inlays with different material required distinct designs. It is important to choose the appropriate material and design of inlay to feat the tooth’s geometry and mechanical conditions of the patient.

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