| 研究生: |
黃家展 Hwang, Chia-Chan |
|---|---|
| 論文名稱: |
台灣繡線菊莖部之成分研究 The Constituents of the Stems of Spiraea formosana |
| 指導教授: |
吳天賞
Wu, Tian-Shung |
| 學位類別: |
碩士 Master |
| 系所名稱: |
理學院 - 化學系 Department of Chemistry |
| 論文出版年: | 2003 |
| 畢業學年度: | 91 |
| 語文別: | 中文 |
| 論文頁數: | 121 |
| 中文關鍵詞: | 單萜類 、三萜類 、二萜類 、繡線菊屬 、台灣繡線菊 、生物鹼 、烏頭屬 |
| 外文關鍵詞: | Aconitum, Spiraea, Rosaceae, formosana |
| 相關次數: | 點閱:218 下載:2 |
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將乾燥的台灣繡線菊莖部 8.60 kg以乙醇萃取六次過濾,並於減壓濃縮除去溶劑後,得到萃取物,將此萃取物分別以氯仿、正丁醇與水進行多次分配萃取,所得之各分配層分別以管柱層析、薄層層析、再結晶方法及高效液相層析法處理,共得到40個化合物,其中39個化合物經光譜分析與文獻比對光譜資料後,確定其化學結構為:agrimonolide, 3-O-β-D-glucosyl-4’,5-dihydroxystilbene, 3,4’,5-trihydro-xystilbene, p-hydroxybenzoic acid, methyl vanillate, p-hydroxybenz-aldehyde, veratric acid, syringic acid, nonadecyl ferulate, p-hydroxy-cinnamaldehyde, methyl ferulate, ethyl p-hydroxy-trans-cinnamate, ethyl ferulate, bakuchiol, (-)-isolariciresinol-3a-O-β-D-glucopyranoside,aurantiamide acetate, N,N-dimethyladenine, methyl quinate, (+)-5,7-dihydroxy-2-(3’,4’-methylenedioxyphenyl)chroman-4-one, β-sitosterone,sitgmasterol與β-sitosterol混合物, 3-O-β-D-glucosyl-p-vanillic acid,vanillic acid, uridine, nanodecyl-3-(4-hydroxy-phenyl)propioate, β-sitosterol, glutinol, β-amyrin, quercetin-3-O-β-D-glucopyranoside,quercetin, quercetin-3-O-β-D-galactopyranoside, kaempferol-3-O-β-D-glucopyranoside, p-coumaric acid, β-sitosteryl glucoside 。其中,spiraeaine A、spiraformin-A~D等5個為天然界首次發現之新化合物。
The dried stems of Spiraea formosana (8.60 Kg) were extractdwith EtOH, and then concentrated under reduce pressure to give darkbrown crude extract 1.02 kg. The crude extract was partitioned bet-ween H2O and CHCl3, and then with n-BuOH. Forty compounds were isolated from each partitioned fraction of this plant by usuallychromatographic methods. The structure of thirty-nine compounds were determined by spectral analysis and chemical transformation.
They are agrimonolide, 3-O-β-D-glucosyl-4’,5-dihydroxystil-bene, 3,4’,5-trihydroxystilbene, p-hydroxybenzoic acid, methyl vanill-ate, p-hydroxybenzaldehyde, veratric acid, syringic acid, nonadecyl ferulate, p-hydroxycinnamaldehyde, methyl ferulate, ethyl p-hydroxy-trans-cinnamate, ethyl ferulate, bakuchiol, (-)-isolariciresinol-3a-O-β-D-glucopyranoside, aurantiamide acetate, N,N-dimethyladenine, me-thyl quinate, (+)-5,7-dihydroxy-2-(3’,4’-methylenedioxyphenyl)chro-man-4-one, β-sitosterone, mixture sitgmasterol and β-sitosterol, 3-O-β-D-glucosyl-p-vanillic acid, vanillic acid, uridine, nanodecyl-3-(4-hydroxyphenyl)propioate, β-sitosterol, glutinol, β-amyrin, quercetin-3-O-β-D-glucopyranoside, quercetin, quercetin-3-O-β-D-galactopyrano-side, kaempferol-3-O-β-D-glucopyranoside, p-coumaric acid, β-sitoster-yl glucoside. Among them, new compounds, spiraeaine A and spira-formin-A~D were isolated from natural source for the first time.
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