本研究之目的在於如何運用微流體技術，在微流道之中穩定的生成直徑1 ~ 10 microns大小的自組裝磷脂質微米管。在本文中生成的磷脂質微米管的方法是源於利用緩衝水溶液水合乾燥之磷脂質薄膜，使磷脂質薄膜在水溶液中自組裝產生封閉多層膜管狀結構也稱為磷髓脂圖，再驅動流體帶動並生成此一管狀結構。
研究使用的晶片是使用微機電系統製程中的厚膜光阻技術SU-8來製作PDMS微流道的母模。在本文中也提出了如何利用”二次翻模”的技術，快速製作出機械性質良好的環氧樹脂晶片。
在實驗設計方面我們探討了一些可能會對磷脂質微米管生成產生影響的因子，並針對微流道中的流體現象與磷脂質管成長之關係加以討論。偵測方式主要以螢光染劑配合螢光顯微鏡觀察實驗結果，另外再以共軛焦顯微鏡及掃瞄式電子顯微鏡做為輔助觀察實驗結果的工具。此自組裝生成的脂質微米管，有著可大量生成及自我導向的優點，可望在奈米碳管之外的技術中利用由下而上的技術建立類生物體的奈米結構，且應用於生物工程提供奈米粒子傳輸路徑上的發展。

In this study we utilized the pressure gradient method stably forming self assembly phospholipid microtubes that are from 1 to 10 microns in diameter in the microchannel. The forming method of this study is based on hydrating dried phospholipid thin film.to form self assembly multi-lamellae tube structures so called myelin figures in solution.
In this study we used micro electro-mechanical systems (MEMS) technology to fabricate SU-8 molds and “polydimethylsiloxane (PDMS)” microfluidic chips. Also in this research we proposed how to rapidly produce EPOXY chips that have good mechanical properties by “two times replicated” method.
Furthermore, at the experiments we discussed some factors which would possible influence the forming process and relations between the fluid phenomena and the lipid tube forming process. We mainly used fluorescence microscope to observe the experiment results and aided confocal microscope and scanning electron microscope (SEM) to make advance observation. This self assembly lipid tubes have advantages of large growth and self aligned. We wish it could be improve nanoparticles transmission in bioengineering.

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