本研究主要以光散射實驗分析電紡絲液柱及內部微結構的大小。藉由聚(異丙基丙烯醯胺)的水溶液為研究載體，探討在不同濃度溫度下電紡絲製程的變化。首先以高速攝影機觀察其電紡絲液柱的瞬間變化，並搭配掃描式電子顯微鏡研究電紡所得的纖維型態，接著希望從光散射實驗找出這些液柱內微結構對於散射強度分布的貢獻。

以光散射實驗取得兩種組成電紡液柱不同位置的散射強度分布實驗值，希望結合Mie theory與本實驗室推導的微結構理論方程式來分析電紡液柱與液柱內微結構散射強度分布的貢獻，並與兩種基礎的微結構理論進行比較。以Mie theory與兩種微結構理論方程式擬合散射強度分布實驗值時，需要一個適用的工具協助，從數學意義上在不同的變數組合中選出最佳解，因此希望藉由matlab程式將三種理論散射強度分布結合起來擬合散射強度分布實驗值，使用窮舉搜尋法搭配物理條件的限制提升尋找最佳解的效率，並賦予最佳解物理意義，避免徒具數學意義。事實上，與基礎的兩種微結構理論相比，本實驗室推導的微結構理論方程式具有相當大的不同，還需要更多關於微結構的物理條件限制才能使最佳解更貼近真實的電紡液柱及內部微結構系統。

In this study, the effects of concentration and temperature on aqueous solution of poly(N-isopropyl acrylamide) during electrospinning had been thoroughly investigated. By means of high speed camera, the momentary change of Taylor-cone and spinning jet had been successfully captured, and discovered phase separation evidences.

Considering the exisiting micro structure in the spinning jet, using light scattering to acquire scattering intensity profiles alonging liquid jet is a feasible way to realize the microstructural composition inside the liquid jet. To fit the intensity profile we got from lightscattering, several scattering intensity distribution theories were used, including Mie theory for jet diameter, string-like and RGB theory for string microstructure, ellipsoid-like and DB theory for ellipsoid microstructure. In order to obtain the optimized result, also attempted to use matlab program to fit experiment data.

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