在循環腫瘤細胞的捕獲研究中，由於檢體中細胞數量很少，所以造成細胞捕獲上非常困難，而近年來使用的檢測方式捕獲效率也不高，且檢測方法也相當耗時、昂貴，因此近年越來越多研究奈米結構對於細胞的影響，且有研究證明奈米結構能夠提升細胞抓取。因此，本研究中希望使用簡單快速的方法進行聚碳酸酯材料拉伸結構的製作，並討論在不同溫度下奈米結構的拉伸效果，之後利用高度提升後的聚碳酸酯拉伸結構進行膀胱癌細胞的捕抓，比較有無結構、親水性處理、不同結構高度，以及細胞培養環境的探討，最後想藉由區域性表面電漿共振量測折射率變化的方式，進一步輔助驗證使用拉伸結構實驗的結果。
最後，本研究中成功地將奈米柱高度提升至原先高度的兩倍，且應用在癌細胞捕獲上，與正常細胞的貼附比也可達到6倍的差異，以及使用懸浮之奈米金圓盤結構在量測到106個癌細胞能有明顯的位移結果。

In this study, we used a simple method to fabricate high aspect ratio polymer nanohairs on polycarbonate substrate by nanoimprint. The height of the PC nanopillars could be stretched to twice of their original size. The attachment rate of T24 cells are above 40% in PBS by the stretched PC substrate.

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