| 研究生: |
廖家樑 Liao, Chia-Liang |
|---|---|
| 論文名稱: |
抗菌型鈣基骨泥之微結構及性質研究(I) Investigation of microstructure and properties of antibacterial calcium-based bone cement (I) |
| 指導教授: |
朱建平
Ju, Chien-Ping 陳瑾惠 Chern Lin, Jiin-Huey |
| 學位類別: |
碩士 Master |
| 系所名稱: |
工學院 - 材料科學及工程學系 Department of Materials Science and Engineering |
| 論文出版年: | 2016 |
| 畢業學年度: | 104 |
| 語文別: | 中文 |
| 論文頁數: | 63 |
| 中文關鍵詞: | 鈣基骨泥 、抗菌 |
| 外文關鍵詞: | Calcium-based bone cement, antibacteriale |
| 相關次數: | 點閱:117 下載:0 |
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為了降低骨科、牙科手術術後感染的風險,本實驗進行抗菌型骨泥的探討,選擇A粉末當抗菌劑加入具有良好生物相容性與骨誘導性的鈣基骨泥複合材中。
本實驗選擇將A粉末化合物添加入鈣基骨泥複合材中,進行對抗菌型骨泥的崩解性質、工作時間、硬化時間及抗壓強度的討論,選擇合適臨床使用的之抗菌型鈣基骨泥條件來進行基本性質的討論。
實驗結果表明,添加越高比例的E粉末進入抗菌型鈣基骨泥,可改善崩解性;調整骨泥使用的液粉比,可以改善崩解性、工作時間與硬化時間;調整硬化劑H粉末水溶液的濃度,亦可明顯改善抗菌型鈣基骨泥之崩解性、工作時間、硬化時間與抗壓強度;改變F粉末粒徑大小,也可以縮短工作時間與硬化時間。
抗菌型鈣基骨泥,研究後發現在混和硬化劑並充分攪拌1分鐘後,即使靜置也不會影響其抗壓性質表現,基底為高生物相容性的鈣基骨泥複合材,於臨床使用上有很大的潛力。
Calcium-based bone cement is widely used in dental and orthopedic applications because its good biocompatibility and osteoinduction. The CMRT Lab developed calcium-based bone cement which has high early strength and non-disperse property unlike conventional CPCs. In order to reduce the risk of postoperative infection in orthopedic and dental surgery, we add antibacterial agent into the Calcium-based bone cement and we adjust the component ratio and the particle size of antibacterial calcium-based bone cement to find better property for medical use.
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校內:2021-08-01公開