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研究生： 謝坤庭
Hsieh, Kun-Ting
論文名稱： 表面起始聚合疏水性高分子與四級銨鹽修飾於棉纖維表面之表面特性及其抗菌與防污之研究
Surface modification of cotton cellulose substrates by hydrophobic polymer with quaternary ammonium functionality: Surface characterization, antibacterial and antistain evaluation
指導教授： 林睿哲
Lin, Jui-Che
學位類別： 碩士
Master
系所名稱： 工學院 - 化學工程學系
Department of Chemical Engineering
論文出版年： 2019
畢業學年度： 107
語文別： 中文
論文頁數： 89
中文關鍵詞： 棉纖維 、表面改質 、四級銨鹽 、疏水性 、殺菌 、抗菌貼附 、防污
外文關鍵詞： quaternary ammonium salt, hydrophobicity, bactericidal, antimicrobial adhesion, anti-stain
相關次數： 點閱：46  下載：2 
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    • 現代人逐漸重視健康，除了飲食選擇謹慎外，對抗病菌也成為一門顯學，這股趨勢下許多具有抗菌的產品也逐漸推出。由於抗菌的需求，抗菌材料越來越受到重視，而一個理想的纖維，除了基本的保暖外，也必須具有抗菌、防水、防污等多功能性質。
    在此選擇棉織物作為基材，於棉纖維表面固定鏈轉移劑，後續透過表面起始可逆加成斷裂鏈轉移聚合引入疏水性單體2,2,2-Trifluoroethyl methacrylate (TFEMA)和具有抗菌能力的四級銨鹽quaternary ammonium salts 2-(Dimethylamino)ethyl methacrylate (DMAEMA+)並建構出具防水、防污、殺菌及抗菌貼附的表面。透過掃描式電子顯微鏡(SEM)、X射線光電子能譜學(XPS)和接觸角測量(WCA)觀察其表面型態、表面鍵結、表面元素組成、表面親疏水性、改質層穩定性，再分別以防污實驗、殺菌實驗及細菌貼附實驗來觀察其效果。
    綜合各實驗結果分析可以確定成功於棉纖維上改質，表面性質都有觀察到明顯的變化，包括表面的型態、鍵結的改變、元素組成的比例，且表面形成接近超疏水的型態，對於防污也有顯著的效果，後續殺菌及抗菌貼附也可以發現改質過後的表面與未改質的表面相比，殺菌率上升，細菌貼附量下降，成功製備出具有抗菌、防污多功能性棉纖維。

    Modern people gradually pay attention to their health. In addition to careful choice of diet, antibacterial has become a knowledge. Due to the demand for antibacterial, antibacterial materials have draw more and more attention, and an ideal fiber, in addition to basic warmth, must also have antibacterial, waterproof, antistain and other multifunctional properties.
    Here, the cotton fabric is selected as the substrate, the chain transfer agent is fixed on the surface of the cotton fiber, and the hydrophobic monomer 2,2,2-Trifluoroethyl methacrylate (TFEMA) and the antibacterial ability quaternary ammonium salt 2-(Dimethylamino)ethyl methacrylate (DMAEMA ) were polymerized from cellulos cotton fiber via reversible addition-fragmentation chain transfer (RAFT) polymerization to provide a surface that is waterproof, stain-resistant, bactericidal and antibacterial adhesion. The surface characterization was analyzed by SEM, XPS and WCA. Furthermore, the bactericidal effect and antibacterial adhesion effect were examined by antimicrobial test.
    According to the results, the surface characterization including element composition, bonding and hydrophobicity was changed after grafting TFEMA and DMAEMA .
    It could be noticed that the amounts of bacteria adhesion reduced dramatically after modification. The treated cotton fiber possessed sufficient antibacterial properties against Staphylococcus aureus and Escherichia coli.
    Thus, the modification was successful and the surface had a great antibacterial and antistain effect.

    摘要 I 目錄 XXV 表目錄 XXVIII 圖目錄 XXIX 第一章 緒論 1 第二章 文獻回顧 3 2-1抗菌纖維 3 2-1-1抗菌纖維的必要性 3 2-1-2抗菌纖維表面 4 2-2棉纖維 6 2-2-1多功能棉纖維 6 2-3 棉纖維表面改質方法 7 2-2-1物理吸附(physisorption) 7 2-2-2化學吸附(chemisorption) 9 2-4 釋放型抗菌 12 2-2-1銀離子 12 2-2-2鹵胺類 14 2-5接觸型抗菌 19 2-5-1殼聚醣 19 2-5-2四級銨鹽 20 2-5-3雙電性離子系列 23 2-5-4超疏水系列 25 2-6可逆加成-斷裂鏈轉移聚合 32 2-6-1活性自由基聚合簡介 32 2-6-2可逆加成-斷裂鏈轉移聚合機理 34 2-2-3表面可逆加成-斷裂鏈轉移聚合 35 2-7 細菌學[69] 37 2-7-1細菌細胞壁的差異 38 2-7-2細菌生長週期 39 2-7-3細菌的培養基 41 2-8 研究目的與動機 42 第三章 實驗藥品與儀器 43 3-1藥品清單 43 3-1-1鏈轉移劑合成 43 3-1-2表面改質 43 3-1-3細菌實驗 44 3-2實驗儀器 45 第四章 實驗步驟 46 4-1流程圖 46 4-2鏈轉移劑合成 47 4-2-1反應流程 47 4-2-2合成CTA[72] 47 4-3棉纖維表面前處理 48 4-3-1反應流程 48 4-3-2前處理 48 4-4轉移劑固定於棉纖維表面 49 4-4-1反應流程 49 4-4-2轉移劑固定[73] 49 4-5製備四級銨鹽預聚物 50 4-5-1反應流程 50 4-5-2合成DMAEMA+ 50 4-6棉纖維表面聚合 51 4-6-1反應流程圖 51 4-6-2表面聚合 51 4-7表面特性分析 52 4-7-1 XPS 52 4-7-2 SEM 52 4-7-3靜態接觸角量測 52 4-8防水、防污測試 53 4-9細菌殺菌實驗 53 4-10細菌貼附實驗 54 第五章 結果與討論 55 5-1 鏈轉移劑結構鑑定 55 5-2 表面特性分析 56 5-2-1 SEM 56 5-2-2 XPS 57 5-2-3表面親疏水性分析 67 5-3防水、防污測試 71 5-4細菌殺菌實驗 72 5-5細菌貼附實驗 74 第六章 結論 81 參考文獻 82

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