| 研究生: |
廖士綱 Liao, Shih-Kang |
|---|---|
| 論文名稱: |
腦多孔彈性模型的混合解析和數值方法 A Mixed Analytical and Numerical Method for Brain Poroelastic Models |
| 指導教授: |
舒宇宸
Shu, Yu-Chen |
| 學位類別: |
博士 Doctor |
| 系所名稱: |
理學院 - 數學系應用數學碩博士班 Department of Mathematics |
| 論文出版年: | 2020 |
| 畢業學年度: | 108 |
| 語文別: | 英文 |
| 論文頁數: | 64 |
| 中文關鍵詞: | 多室多孔彈性模型 、腦力學 、解析解 |
| 外文關鍵詞: | multicompartmental poroelastic model, Cerebral Poromechanics, Analytical Solution |
| 相關次數: | 點閱:143 下載:11 |
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在這項研究中,我們為腦多孔彈性模型提出了一種混合分析和數值方法。單網絡和多室多孔彈性模型被用來描述大腦組織位移和各種腦脊液壓力的相互作用。通過匹配邊界條件,導出了解析的穩態通解,並透過邊界條件對係數進行了數值求解。對於動力學問題,採用交錯網格的有限差分法消除了非物理振動。 數值實驗表明穩態解的二階收斂性。得到當在邊界上施加衝擊時,腦質裡波傳輸的模擬。結果表明,該波被吸收並收斂到穩態解。
In this study, we proposed a mixed analytical and numerical method for brain poroelastic models. Single-network and multicompartmental poroelastic models are applied to describe the interaction between the displacement of the brain tissue and the pressure of various cerebrospinal fluid. General solutions of the steady state are derived analytically, and the coefficients are solved numerically to agree with the boundary conditions. For dynamical problems, non-physical oscillation is eliminated by finite difference method with staggered grid. The numerical experiments show the second-order convergence for the steady state solutions. Wave transmission in brain is observed when an impact is applied to the boundary. The results show that the wave decays in time, and the displacement eventually converges to the steady state.
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