本研究透過共沉澱法在具有良好的導電性、高比表面積以及三維開孔結構的泡沫鎳 (Ni foam) 上，製備具有鐵氰化銅修飾層的泡沫鎳電極 (CuHCF/NF)，並應用於電催化槲皮素 (QR) 氧化反應。
透過調控製備鐵氰化銅結構共沉澱過程的實驗參數進行最佳化，其影響變因有CuCl2：K3Fe(CN)6濃度比例、檸檬酸鈉濃度、共沉澱反應溫度、共沉澱反應時間以及乾燥方法，再分別藉由高解析度掃描式電子顯微鏡 (SEM)、X光能量分散式光譜分析儀 (EDS)、X射線繞射儀 (XRD) 以及循環伏安法對CuHCF進行表面形貌、元素組成、晶體結構以及對於催化槲皮素電化學之分析。最佳化條件分別為1：1.5的CuCl2：K3Fe(CN)6濃度比例為、15 mM檸檬酸鈉以及在25℃下沉積60分鐘，反應完後在25℃下乾燥15小時，另外，與電沉積法相比共沉澱法製備之電極具有更佳的催化活性，後續以最佳化條件製備的CuHCF/NF電極進行槲皮素之感測。透過EDS mapping以及XRD鑑定最佳化CuHCF/NF電極，觀察到CuHCF均勻的分布在泡沫鎳上，且其XRD訊號顯示出此實驗CuHCF結構中存在有K+。在電催化槲皮素氧化反應方面，與泡沫鎳空白電極相比，顯示CuHCF/NF電極對於槲皮素具有催化效果，其線性範圍為0.02 μM至70 μM (ip = 4.3768[QR]+116.0100, R2  0.998)，偵測極限為0.017 μM。

In this work, a copper hexacyanoferrate modified layer was prepared on the nickel foam (CuHCF/NF) by co-precipitation method, and applied to quercetin detection. Optimization of the experimental parameters for the preparation of CuHCF structures depend on CuCl2 and K3Fe(CN)6 concentration ratio, trisodium citrate concentration, co-precipitation reaction temperature and reaction time. Scanning electron microscope (SEM), energy-dispersive X-ray spectroscopy (EDS), X-ray diffractometer (XRD) and cyclic voltammetry (CV) were employed to characterize the preparation process of the CuHCF/NF electrodes. Under optimized conditions, CuHCF/NF electrodes showing electrocatalytic ability toward the oxidation of Quercetin (QR) compared with the nickel foam electrode. The linear range of QR were 0.02 μM-70 μM and a lower limit of detection of 0.017 μM.

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