在本論文研究中，以水溶性硫酸鈉奈米線作為模板，利用溶膠凝膠法，選擇適當的溶劑比例，在四乙氧基矽水解之後，加入氫氧化鈉催化聚合之，再以水溶解硫酸鈉奈米線，移除模板之後，即可製得二氧化矽奈米管，其中也藉由水解時間的改變，調控二氧化矽奈米管的管壁厚。
反應環境為pH值＞2下聚合的二氧化矽，其表面將帶有負電荷，故可以靜電吸引力的方式，與以共沉澱法製備並表面帶有正電荷的四氧化三鐵結合，繼而於其表面修飾上3-丙胺三乙氧基矽烷後，將使二氧化矽-四氧化三鐵奈米管外露胺基，且表面帶正電。
使用氧化還原法製得奈米金作為晶種，由於使用檸檬酸鈉作保護劑，其表面將帶有羧基，並帶有負電，因此利用靜電吸引力及使用連結劑，讓金晶種與二氧化矽-氧化鐵奈米管做靜電吸引力及共價鍵的結合。接著加入金成長液，並以甲醛作還原劑，使金還原於二氧化矽-氧化鐵奈米管的表面，形成金殼層，金殼層的緻密度可藉由不同量的金成長液調控，且其在近紅外光區的吸收度也將因不同成長液的量而改變。此複合材料將兼具磁性及光學性質，並可應用於磁共振顯影，以及光熱治療上。

In this study, SiO2 nanotubes were produced by using the water dissolvable sodium sulfate nanowires as hard template. SiO2 nanotubes could be synthesized by hydrolysis of tetraethoxysilan (TEOS) on the surface of Na2SO4 nanowires, followed by removal of Na2SO4 nanowires with H2O. The wall thickness of SiO2 nanotubes could be tuned by the change of the hydrolysis time of TEOS.
Because of negative charge on the surface of SiO2 nanotubes, positively charged Fe3O4 nanoparticles could be deposited by electrostatic interaction. The -NH2 functional groups on the surface of SiO2/Fe3O4 nanotubes were functionalized with 3-aminopropyl-triethoxysilane（APTES）for the purpose of synthesis of SiO2/Fe3O4/Au nanotubes.
Subsequently, Au seeds were fabricated by oxidation reduction method with protective agent sodium citrate. 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride (EDC) was added to conjugate the -NH2 of SiO2/Fe3O4 nanotubes and the –COOH groups existing onto Au seeds for the amide bonds formation. Finally, the Au growing stock solution was introduced to form Au nanoshell. It was focused that the near infrared (NIR) absorbance of the SiO2/Fe3O4/Au nanotubes depended on the compactness of the Au shell.

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