本實驗使用與CMRT(Cana Materials Research Team)研究團隊開發的多孔性calcium-based bone substitute(CBS)相同基底成分，希望能夠在維持相同優秀的物化和生物性質下，研發柱狀多孔鈣基骨取代物(CBSR)，使其表面具有緻密層能夠阻擋軟組織進入，讓骨細胞有良好的生長空間。
本實驗第一部分為將藉由改變製程參數增加緻密層連續比例，其緻密層連續比例達97.63%，抗壓強度和孔隙率分別為2.18MPa和78.72%之孔隙率，進行第二部分實驗，藉由改變CBC與硬化劑的比例試圖繼續增加緻密層連續比例，而找到最佳條件為製程參數C-3，緻密層連續比例達99.01%，同時抗壓強度和孔隙率也達2.16MPa、79.85%。

CBS(calcium-based bone substitute) developed by CMRT(Cana Materials Research Team) has excellent physical properties, chemical properties, and biocompatibility. We use the same raw materials as CBS to make rod-shaped porous calcium-based bone substitutes and a dense layer, which prevents excessive penetration of fibrous tissue into the bone defect, can be formed on the surface.
Using the compression process makes a dense layer appear on the surface. The experimental results showed that it has high porosity, enough compressive strength, and high dense layer continuity.

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