工業的蓬勃發展，帶動製造業快速地成長，也對全球的經濟做出重要的貢獻。然而產品複雜的生產過程與廢棄物的產生，卻也替人類帶來難以想像的健康危害與環境浩劫。多數中小企業具有短的產品週期或小的生產流程特性，在進行產品環境概念設計時，由於成本的考量，毒理學家或環境專家常難以駐廠，故需要一種容易使用且時間效率高的工具來有效因應當前的困境。
本研究首先就德國毒性潛能指標（Toxic Potential Indicator, TPI）在台灣初步應用遭遇的問題點進行探究，再配合中文物質安全資料表（Material Safety Data Sheet, MSDS）的使用，訂出各項資料選用準則，另依MSDS的格式，重新對物質危害類別進行系統性的分類，以符合中文MSDS的使用。接著去除較不適用台灣法令之評估項目後，提出新的台灣毒性潛能指標（Taiwan Toxic Potential Indicator, Taiwan-TPI），此評估模式不僅適用於中文的MSDS，其他非英語系國家的MSDS亦可參考使用。最後則參考化學品全球分類及標示調和制度（Globally Harmonized System of Classification and Labelling of Chemicals, GHS）所規範於MSDS之危害物質分類，提出全世界適用的危害潛能指標（Hazardous Potential Indicator, HPI）評估方法。HPI是根據GHS全球統一分類結果，不會受到各國法規、文化、語言和習慣等影響，故能獲得一致的評估結果。
整體而言，本研究提出的幾種由MSDS為依據所建立的材料潛能指標方法，可藉由容易且直接的方式，避開繁瑣的毒理學判斷與複雜的生命週期盤查，為一種量化的定性指標，恰可提供工程師在進行綠色設計時，作為在比較和選用材料或零件時，一種較簡單且省時間的可靠評估工具。

Industrial revolution has resulted in the rapid growth of product manufacturing, and this growth has made an important contribution to world economy. Because of the complexity of product manufacturing processes and their waste streams, products may post hazard to environment and human health.
Typical small and medium-sized enterprises, which tend to have shorter product cycles, cannot afford staffing toxicologists or environmental specialists in the companies’ product design divisions. These enterprises need an easy-to-use and time-efficient tool for environmentally conscious design. The potential indicator methodologies in this dissertation are developed meet such a need. Unlike traditional LCA tools that require need tremendous amount of inventory data, the standard Material Safety Data Sheets (MSDSs) are sufficient to establish the indicators.
Some adjustment techniques to overcome the application issues of the Toxic Potential Indicator (TPI) methodology in Taiwan are proposed first. Then this dissertation proposes a new framework of TPI, named Taiwan Toxic Potential Indicator (Taiwan-TPI), to solve the obstacles arisen from different regulations. It has been shown that the TPI methodology, if properly customized, can be adopted by other countries, including those non-English-speaking ones. Finally, the proposed Hazardous Potential Indicator (HPI) is suitable to all countries that implement the GHS (Globally Harmonized System of Classification and Labelling of Chemicals). Thanks to the GHS, consistent HPI results can be obtained on materials based on different MSDSs. In sum, these potential indicator approaches, based on applicable MSDSs, are simple and direct tools to help product designers compare and select components and materials to reduce the impact to the environment.

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