如何客觀的衡量疾病所帶來的損失，一直以來便是衛生政策決定者及學者所關注的重點。比較疾病間、有無疾病或治療前後的損失差異，能幫助決策者分配有限的資源，或分析治療是否具備成本效益。嚴重特殊傳染性肺炎(COVID-19)為歷史上少見的大規模傳染性疾病，迄今全球已有數億人感染並造成數百萬人死亡。因此，衡量其所帶來的損失至關重要。
本研究使用失能調整人年(Disability-adjusted life years, DALYs)與人力資本法(Human Capital Approach, HCA)衡量此次嚴重特殊傳染性肺炎對民眾健康與經濟的影響。失能調整人年為哈佛大學與世界衛生組織所提出衡量健康損失的方法，為目前衡量疾病損失的主流方法之一，優點為簡單快速且易於比較。經濟損失方面本研究使用人力資本法衡量，人力資本法的特點為由社會的角度來衡量疾病的影響，對於大規模的傳染性疾病較為適合。
研究發現，每千人健康損失男性約為6.49DALYs，女性約為5.32DALYs；經濟損失以人力資本法衡量損失約為83億美元，其中因病被迫離開職場的暫時性損失約為53億美元，而因死亡所導致的永久性損失約為30億美元。

To estimate the impact of communicable diseases on human capital loss, the health policy makers and scholars not only consider the health loss but also productivity loss. This study uses disability-adjusted life years (DALYs) to estimate the health loss and human capital approach (HCA) to estimate the productivity loss. Estimation results indicate that the group aged from 45 to 65 years lost the most productivity or earnings. The group aged above 80 years lost the most DAYLs or health effects.

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