淡水水體常因各類污水的不當排放，造成水體中營養鹽過剩而產生優養化的現象，進而產生大量藍綠菌（或稱藍綠藻）。許多藍綠菌會產生各種有害的代謝物，包括多種的藻毒素（Cyanotoxin）。藻毒素如進入飲用水系統中，將對人體造成傷害。β-甲氨基-L-丙氨酸（β-N-methylamino L-alanine, BMAA）及2,4-二氨基丁酸（2,4-diaminobutyric acid, DAB）和N-(2-氨乙基)甘氨酸（N-(2-aminoethyl) glycine, AEG）等皆為同分異構物，其為胺基酸結構之新型藻類神經毒素，會對生物的神經系統造成傷害。且藻毒素具有生物放大的效應，因此如何能有效地處理此類型藻毒素，是當今民生用水的水處理中一個重要的課題。本研究主要在探討目前用於水處理廠的兩種常見氧化劑：高錳酸鉀（Potassium permanganate, KMnO4）及臭氧（Ozone, O3），是否能有效地去除水中的DAB及AEG。
根據氧化實驗的結果顯示，高錳酸鉀和DAB與AEG反應時，既使溶液內高錳酸鉀的濃度為1、4及5 mg/L，DAB在三小時內仍不會與高錳酸鉀產生有效的反應，而AEG卻會被高錳酸鉀所降解，其降解量隨著高錳酸鉀的濃度升高而升高。亦即，在高錳酸鉀濃度為1 mg/L時有30～50 %的AEG被降解；尤其當pH=7時，具有最高的降解量（約為48 %）。而高錳酸鉀在4 mg/L及5 mg/L的濃度下，降解量均超過90%。在臭氧的氧化反應實驗中，因臭氧與DAB和AEG的反應速度均極快，因此利用添加2-氯-4甲氧基苯酚（4-Chloroguaiacol，4-CG）進行競爭實驗。實驗結果顯示，臭氧相較於高錳酸鉀對AEG和DAB皆具有較佳的氧化能力。

In this study, DAB (2,4-diaminobutyric acid) and AEG (N-(2-aminoethyl) glycine), produced by cyanobacteria of the water eutrophication algae; i.e., cyanotoxins, were oxidized by permanganate and ozone with various levels of concentration and pH value. The analyses were done to investigate whatever the different oxidants in whichever situations are giving better efficiency in removing the DAB and AEG within the water body.

It was shown that the permanganate can’t efficiently oxidize the DAB, even raise the concentration of permanganate. The AEG would be removed with a longer time and higher concentration of permanganate. It may because of DAB and AEG are both having no double-bond structure such that the permanganate have no target to attack, therefore the hydroxylation cannot occur. Nevertheless, oxidation of glycine by permanganate ion in the aqueous phosphate buffers has shown that an auto-catalysis has occurred by the soluble form of colloidal manganese dioxide, which was formed as the reaction product. Namely, it gives the permanganate to be able to eliminate AEG. In addition, due to the oxidation reaction by ozone was very fast either for DAB or for AEG. The rate constant between ozone and DAB (or AEG) was found to be pH dependent; namely, when the pH is raised, both of their rate constants are also increased. The rate constants obtained in this study may serve as a useful reference for water utilities to estimate the removal efficiency; once DAB and AEG are present in the source water.

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