20呎貨櫃在緊急時刻應用於醫療用途上具有改造價值，但其壓力保護措施設計方法、參考資料與相關案例仍不足，以此為契機，本研究分析人員進出貨櫃內部空間正負壓力變化，並總結在各種不同使用目的下壓力值大小、硬體保護設施設計方案供未來20呎貨櫃改造設計參考。
實驗場域為20呎貨櫃移動式篩檢站，針對硬體設施方面、人為操作兩大項目進行討論，包含換氣次數、前室、內部空間門扇氣密性、前室對外調壓緩衝開口、開關門速度等，貨櫃容積32.67立方公尺，以冷凍隔板(PE)建置臨時前室，設有簡易變頻換氣風扇兩台，可滿足場域2~35ACH，並以數位式壓力偵測器量測正負壓性能，最後將壓力值予以紀錄、統計與分析。
實驗結果總結5點如下
1. 增設前室有效改善內部空間壓力浮動現，但仍有7~10Pa不等的壓力浮動
2. 增加換氣次數有效增加壓力保護水準，但缺乏前室下則毫無幫助
3. 增加內部空間門扇氣密性對壓力保護效果改善不佳
4. 前室對外調壓緩衝開口(面積0.04m2)改善0~7Pa壓力浮動
5. 開關門速度由0.5秒增加至1.0秒改善內部空間0~6Pa壓力浮動現象
最後建議20呎貨櫃若有壓力保護需求，設置前室為必須項目，門扇氣密性不應大於0.02平方公尺，並力求開關門動作和緩。

This study analyzes the positive and negative pressure changes in the internal space of the 20-foot container when personnel enter and exit. The experiment was carried out in a 20-foot container mobile screening station. The indoor size of the experimental field is 5.8 x 2.2m x 2.56m, the indoor area is 12.76square meter, and the internal space volume is 32.67 cubic meter. There are two simple frequency conversion ventilation fans, which can generate 2~35ACH.
The scope of the research focuses on the two major items of hardware facilities and human operation, including the number of ACH, the anteroom, the airtightness of the door leaf in the inner space, the pressure regulating buffer port in the anteroom, and the door opening and closing speed. The experimental method is measured by a digital pressure detector, and then record, count and analyze the pressure value.
The experimental results are summarized in 5 points as follows:
1. anteroom effectively improves the pressure fluctuation in the internal space, but there are still pressure fluctuations ranging from 7 to 10 Pa
2. the addition of ACH effectively increases the level of pressure protection, but not helpful without anteroom.
3. increasing the airtightness of the door leaf in the inner space is not effective for pressure protection
4. anteroom equipped with an external buffer opening (0.04m2) reduce the pressure fluctuation of 0~7Pa
5. The speed of opening and closing the door is increased from 0.5 seconds to 1.0 seconds, effectively improving the pressure fluctuation phenomenon of 0~6Pa.

國內文獻
(1) 曹達和、張振平、莊啓佑、莊侑哲、林升傑、戴聿彤(2011)。病房門縫大小對負壓隔離病房負壓值之影響探討。勞工安全衛生研究季刊，第18卷第三期，306。
(2) 內政部營建署(2021)。建築技術規則建築設備篇。第101條。
(3) 王順智等(2010)負壓隔離病房總體設計與洩漏率研究。行政院勞工委員會勞工安全衛生研究所，P37-38
(4) 行政院勞工委員會勞工安全衛生研究所(2006)。負壓隔離病房作業參考手冊，P10、11。
(5) 董雲春、胡石政(2011)。壓差與換氣次數對負壓隔離病房之通風效率影響。中興工程季刊第111期P71-78
(6) 周英香、白佳原、李亞欣、黃嘉綺、王思璇、游乃祈(2021)。COVID-19 行動防疫醫療站之實務運用。醫管新冠肺炎防疫專刊，第一刊
(7) 葉崇揚(2018)。前室壓力變化對負壓隔離病房性能探討(碩士論文)。長榮大學，臺南市。
(8) 張立山(2016)。正壓隔離病房氣流模擬分析(碩士論文)。國立台北科技大學，台北市。
(9) 宋森恬(2022)。負壓隔離病房之現場量測與數值模擬分析評估(碩士論文)。國立勤益科技大學，臺中市。
(10) 蘇志勳(2004)。一般居室空間改造為負壓隔離病房之換氣效能檢測與預測分析(碩士論文)。國立成功大學，台南市。
(11) 陳春萬、楊金源、鍾基強、陳友剛(2002)。整體換氣壓力差對有害物散布之影響。勞工安全衛生研究季刊，第十卷第二期，109-115。
(12) 行政院衛生福利部(2020)。醫療機構設置標準。附表一(四)醫療服務設施

國外文獻
(1) Ehsan S. Mousavi, Krystal J.Godri Pollitt , Jodi Sherman, Richard A.Martinello(2020). Performance analysis of portable HEPA filters and temporary plastic anterooms on the spread of surrogate coronavirus. Journal of Building and Environment 183.
(2) Liang En Wee MRCP, Monica Peijin Fan BSc,Raphael Heng B.Eng, Shin Yuh Ang MBA, Juat Lan Chiang MHSc, Thuan Tong Tan PhD, Moi Lin Ling FRCPA, Limin Wijaya MRCP (2019). Construction of a container isolation ward: a rapidly scalable modular approach to expand isolation capacity during the coronavirus disease 2019(covid-19) pandemic. The Society for Healthcare Epidemiology of America
(3) U.S. Department of Health and Human Services
Centers for Disease Control and Prevention(2003), Guidelines for Environmental Infection Control in Health-Care Facilities, P33、P223
(4) National Health Service(2021). Health Technical Memorandum 03-01 Specialised ventilation for healthcare premises Part A: The concept, design,specification, installation and acceptance testing of healthcare ventilation systems, p147-148.
(5) Shobha S. Subhash MS, MPH, Gio Baracco MD, FACP, Kevin P. Fennelly MD, MPH, Michael Hodgson MD, MPH, Lewis J. Radonovich Jr. MD(2013), Isolation anterooms Important components of airborne infection control. American journal of infection control 41.
(6) Bin Zhou, Lili Dinga, Fei Lia, Ke Xuea, Peter V. Nielsenb, Yang Xua(2018), Influence of opening and closing process of sliding door on interface airflow characteristic in operating room. Building and Environment. Journal of Building and Environment 144.
(7) Shobha S. Subhash MS, MPH, Gio Baracco MD, FACP, Kevin P. Fennelly MD, MPH, Michael Hodgson MD, MPH, Lewis J. Radonovich Jr. MD(2013). Isolation anterooms: Important components of airborne infection control
(8) ASHARE(2021), Ventilation of Health Care Facilities
(9) Noah J. Adams, MS, David L. Johnson, PhD, and Robert A. Lynch, PhD(2010), The effect of pressure differential and care provider movement on airborne infectious isolation room containment effectiveness. AJIC major articles.
(10) Charles S. Hayden II , Ova E. Johnston , Robert T. Hughes & Paul A. Jensen (2011), Air Volume Migration from Negative Pressure Isolation Rooms during Entry/Exit. Applied Occupational and Environmental Hygiene.
(11) U.S. Department of Health and Human Services Centers for Disease Control and Prevention (CDC) (2003), Recommendations of CDC and the Healthcare Infection Control Practices Advisory Committee (HICPAC).
(12) Bård Venås1, Anders Welde Vikan1, Merethe Cecilie Lind1, Trond Thorgeir Harsem(2019), Air Flow Door Barrier for Airborne Infection Isolation Rooms.
(13) Merethe C. Lind, M.Sc., Dr. Bård Venås, Anders Welde Vikan, M.Sc., Hannu Koskela, Petri Kalliomäki M.Sc., Trond Thorgeir Harsem,M.Sc.(2019), Designing Simplified Airborne Infection Isolation Rooms to Reduce Infection Rate in Future Pandemics. ASHRAE Transactions, Volume 125, Part 2
(14) Joon Kee Lee MD, PhD, Hye Won Jeong MD, PhD(2020), Rapid expansion of temporary, reliable airborne-infection isolation rooms with negative air machines for critical COVID-19 patients. American Journal of Infection Control 48, 822−824.
(15) Elham Andalib, Masoumeh Faghani, Seyyed Mahdi Zia Ziabari, Mohammad Shenagari, Hamid Salehiniya, Mohammad Hossein Keivanlou, Zahra Rafat(2022), The Effectiveness of the Anteroom (Vestibule) Area on Hospital Infection Control and Health Staff Safety: A Systematic Review. Frontiers in Public Health

網路文獻
(1) 華記科技有限公司(2020)。華記J-4500-DP0002N數位式壓力偵測器規格。檢自
https://www.safegauge.com.tw/prod-info/4.html
(2) Fulltech Electric Co., Ltd(2018)。FULLTECH-UF25G11軸流式風扇。檢自
https://www.fulltechtw.com/_en/_Products-Datain.php?id=82
(3) 立紳有限公司(2019)。RiXEN 熱線式風速、風量計 型號:VA5002。檢自
https://www.rixen.com.tw/products_detail/113.htm