近年來世界多數國家生育率降低且壽命延長，人口逐漸老齡化。而這種現象將成為下一個全球性的公共健康挑戰。人口和流行病再加上快速的城市化、現代化、全球化，風險因素和生活方式劇烈的改變，都增加了慢性病的突出。其中，退化性關節炎為影響老年生活的一大主因，患病率隨年齡增高急速增長。在醫學醫療長期對於退化性關節炎研究之下，發現保持良好的姿勢是預防損傷、減輕關節壓力並增加穩定的關鍵因素，而穿戴裝置是目前切入生活最迅速的方式，有提醒監督的效果。因此，如何精準且正確適當的對於使用者進行不良姿勢提醒，並達到降低退化性關節炎患病的機率，仍是需要探索與應用的地方。目前穿戴裝置目的為輔助運動的裝置皆以偵測與機電創新為考量居多，並著重在心律運動資料收集與呈現，較少在探討對於慢性病的預防。本研究秉持以人為本的核心理念，以提升良好足部姿勢達到預防退化性關節炎為主軸，從退化性關節炎成因、關節物理治療方式、人體解剖學足部機構、穿戴裝置與人之互動切入，考慮人的運動與生活習慣，發展出了解內在並於外在及時輔助之穿戴裝置設計，經初步測試後，此穿戴裝置能夠在生活中立即提供身體足態資訊輔助，間接能降低退化性關節炎患病的機率，逐漸改變使用者生活習慣、使身心健康。

In recent years, fertility has declined and life expectancy has risen in most countries of the world. This phenomenon, known as population aging, will become the next global public health challenge. With this trend of aging, chronic diseases have increased and have become a big issue. Due to high percentages of people suffering from disease and increases in life expectancy, Knee Osteoarthritis (KOA) is now considered as one of the most significant causes of disability in the world. Therefore, it is crucial to approach this area in order to solve or reduce risk of KOA among aging people. In a long-term study of KOA conducted by medical researchers, long term of good posture was found to be a key factor to reducing knee stress and increase stability.
With the rapid development of technology, wearable devices (WD) for various personal applications, ranging from entertainment to physiological monitoring, are now seen everywhere. But currently, the existing WD are still focused on information collection, motion detection and electromechanical innovation. In order to design new kinds of WD, this study believes that understanding within a human-centric approach, with intuitive physical or visual feedback will become the next step in WD. Therefore, this study aims to improve knee-wellness with correct and appropriate protection and to reduce the risk of KOA by designing an innovative human factor-based WD for the knee.
In this study we highlight a WD, which is designed from a human-oriented core philosophy. Investigation into KOA causes, Knee physical treatment, human anatomy of the knee, interaction between human and devices will be undertaken. In the end, not only will this device provide comprehensive aid in movement, but it will also reduce the risk of KOA, gradually changing user habits and leading to healthier states. Thus, the purposes of study are (1) Investigate the relationship between posture and knee, and the right posture can decrease the risk of osteoarthritis; (2) Design an innovative wearable device which is able to improve posture and decrease force of bad postures, to achieve stabilize knee and decrease the risk of osteoarthritis; (3)Evaluate the new wearable device design, find out relationship between factors.

Affairs, U. N. D. o. E. a. S. (2015). World Population Prospects: The 2015 Revision, Key Findings and Advance Tables. (ESA/P/WP.241.).
Bonato, P. (2010). Advances in wearable technology and its medical applications. Paper presented at the 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology.
Castillejo, P., Martinez, J.-F., Rodriguez-Molina, J., & Cuerva, A. (2013). Integration of wearable devices in a wireless sensor network for an E-health application. IEEE Wireless Communications, 20(4), 38-49.
Chen, B.-R., Patel, S., Buckley, T., Rednic, R., McClure, D. J., Shih, L., . . . Bonato, P. (2011). A web-based system for home monitoring of patients with Parkinson's disease using wearable sensors. Biomedical Engineering, IEEE Transactions on, 58(3), 831-836.
Chuo, Y., Marzencki, M., Hung, B., Jaggernauth, C., Tavakolian, K., Lin, P., & Kaminska, B. (2010). Mechanically flexible wireless multisensor platform for human physical activity and vitals monitoring. IEEE transactions on biomedical circuits and systems, 4(5), 281-294.
Clearman, R. R. (1992). Functional rehabilitation of the knee. Journal of back and musculoskeletal rehabilitation, 2(1), 14-22.
D'Angelo, L. T., Neuhaeuser, J., Zhao, Y., & Lueth, T. C. (2014). SIMPLE-use—Sensor set for wearable movement and interaction research. IEEE Sensors Journal, 14(4), 1207-1215.
Deyle, G. D., Allison, S. C., Matekel, R. L., Ryder, M. G., Stang, J. M., Gohdes, D. D., . . . Garber, M. B. (2005). Physical therapy treatment effectiveness for osteoarthritis of the knee: a randomized comparison of supervised clinical exercise and manual therapy procedures versus a home exercise program. Physical therapy, 85(12), 1301-1317.
Kalantarian, H., Alshurafa, N., Le, T., & Sarrafzadeh, M. (2015). Monitoring eating habits using a piezoelectric sensor-based necklace. Computers in biology and medicine, 58, 46-55.
Kan, Y.-C., & Chen, C.-K. (2012). A wearable inertial sensor node for body motion analysis. IEEE Sensors Journal, 12(3), 651-657.
Lattanzio, F., Abbatecola, A. M., Bevilacqua, R., Chiatti, C., Corsonello, A., Rossi, L., . . . Bernabei, R. (2014). Advanced technology care innovation for older people in Italy: necessity and opportunity to promote health and wellbeing. Journal of the American Medical Directors Association, 15(7), 457-466.
Lawrence, J., Bremner, J., & Bier, F. (1966). Osteo-arthrosis. Prevalence in the population and relationship between symptoms and x-ray changes. Annals of the rheumatic diseases, 25(1), 1.
Mariani, B., Jiménez, M. C., Vingerhoets, F. J., & Aminian, K. (2013a). On-shoe wearable sensors for gait and turning assessment of patients with Parkinson's disease. IEEE transactions on biomedical engineering, 60(1), 155-158.
Mariani, B., Jiménez, M. C., Vingerhoets, F. J., & Aminian, K. (2013b). On-shoe wearable sensors for gait and turning assessment of patients with Parkinson's disease. Biomedical Engineering, IEEE Transactions on, 60(1), 155-158.
Munro, B. J., Campbell, T. E., Wallace, G. G., & Steele, J. R. (2008). The intelligent knee sleeve: A wearable biofeedback device. Sensors and Actuators B: Chemical, 131(2), 541-547.
Musumeci, G., Aiello, F. C., Szychlinska, M. A., Di Rosa, M., Castrogiovanni, P., & Mobasheri, A. (2015). Osteoarthritis in the XXIst Century: Risk Factors and Behaviours that Influence Disease Onset and Progression. International journal of molecular sciences, 16(3), 6093-6112.
Musumeci, G., Castrogiovanni, P., Trovato, F., Imbesi, R., Giunta, S., Szychlinska, M., . . . Mobasheri, A. (2015). Physical activity ameliorates cartilage degeneration in a rat model of aging: A study on lubricin expression. Scandinavian journal of medicine & science in sports, 25(2), e222-e230.
Musumeci, G., Loreto, C., Imbesi, R., Trovato, F. M., Di Giunta, A., Lombardo, C., . . . Castrogiovanni, P. (2014). Advantages of exercise in rehabilitation, treatment and prevention of altered morphological features in knee osteoarthritis. A narrative review. Histology and histopathology, 29(6), 707-719.
Musumeci, G., Szychlinska, M. A., & Mobasheri, A. (2015). Age-related degeneration of articular cartilage in the pathogenesis of osteoarthritis: Molecular markers of senescent chondrocytes. Histol. Histopathol, 30, 1-12.
Patel, S., Lorincz, K., Hughes, R., Huggins, N., Growdon, J., Standaert, D., . . . Bonato, P. (2009). Monitoring motor fluctuations in patients with Parkinson's disease using wearable sensors. Information Technology in Biomedicine, IEEE Transactions on, 13(6), 864-873.
Pichler, K., Loreto, C., Leonardi, R., Reuber, T., Weinberg, A., & Musumeci, G. (2013). In rat with glucocorticoid-induced osteoporosis, RANKL is downregulated in bone cells by physical activity (treadmill and vibration stimulation training). Histol Histopathol, 28, 1185-1196.
Ramos, Y. F., den Hollander, W., Bovée, J. V., Bomer, N., van der Breggen, R., Lakenberg, N., . . . Nelissen, R. G. (2014). Genes involved in the osteoarthritis process identified through genome wide expression analysis in articular cartilage; the RAAK study.
Reynard, L. N., & Loughlin, J. (2012). Genetics and epigenetics of osteoarthritis. Maturitas, 71(3), 200-204.
Ritchey, T. (1998). General morphological analysis. Paper presented at the 16th euro conference on operational analysis.
Ritchey, T. (2002). Modelling complex socio-technical systems using morphological analysis. Adapted from an address to the Swedish Parliamentary IT Commission, Stockholm.
Ritchey, T. (2006). Modeling multi-hazard disaster reduction strategies with computer-aided morphological analysis. Paper presented at the Reprint from the Proceedings of the 3rd International ISCRAM Conference, Newark, NJ.
Sanchez-Ramirez DC, v. d. L. M., van der Esch M, Roorda LD, Verschueren S, van Dieën J, Lems WF, Dekker J. (2015). Increased knee muscle strength is associated with decreased activity limitations in established knee osteoarthritis: Two-year follow-up study in the Amsterdam osteoarthritis cohort. J Rehabil Med, 47, 647–654.
Sazonov, E. S., Fulk, G., Hill, J., Schutz, Y., & Browning, R. (2011). Monitoring of posture allocations and activities by a shoe-based wearable sensor. IEEE transactions on biomedical engineering, 58(4), 983-990.
Shany, T., Redmond, S. J., Narayanan, M. R., & Lovell, N. H. (2012). Sensors-based wearable systems for monitoring of human movement and falls. IEEE Sensors Journal, 12(3), 658-670.
Silverwood, V., Blagojevic-Bucknall, M., Jinks, C., Jordan, J., Protheroe, J., & Jordan, K. (2015). Current evidence on risk factors for knee osteoarthritis in older adults: a systematic review and meta-analysis. Osteoarthritis and Cartilage, 23(4), 507-515.
Suryadevara, N. K., Mukhopadhyay, S. C., Kelly, S. D. T., & Gill, S. P. S. (2015). WSN-Based Smart Sensors and Actuator for Power Management in Intelligent Buildings. Mechatronics, IEEE/ASME Transactions on, 20(2), 564-571.
Suzman, R., Beard, J. R., Boerma, T., & Chatterji, S. (2015). Health in an ageing world—what do we know? The Lancet, 385(9967), 484-486.
Veltink, P. H., & De Rossi, D. (2010). Wearable technology for biomechanics: e-textile or micromechanical sensors?[conversations in bme]. IEEE engineering in medicine and biology magazine, 29(3), 37-43.
Wewers, M. E., & Lowe, N. K. (1990). A critical review of visual analogue scales in the measurement of clinical phenomena. Research in nursing & health, 13(4), 227-236.
Zwicky, F. (1967). The morphological approach to discovery, invention, research and construction New methods of thought and procedure (pp. 273-297): Springer.