生物分子馬達乃一種特殊的酵素蛋白，包含了一般酵素蛋白所具有加速催化受質的能力，以及對外做功的能力。馬達蛋白利用的能量來源乃是儲存於ATP中的化學能。而馬達蛋白的構形在鍵結過程以及催化過程均有所變化，這些變化直接地影響馬達蛋白對外界的出力以及動作狀態，進而使得生物分子馬達得以對外做功。

本文提出不可逆性因子耦合器的概念，來解釋處於線性非平衡態熱力學過程中的生物分子馬達，在鍵結過程中蒐集系統外界的不可逆性。而處於線性非平衡態區的分子馬達，將會遵循最小熵增定律，因此本文猜測若如本文所言，將可發現熵增穩定以及熵增維持在低值的情況出現。因此我們使用兩篇實驗數據來佐證本文的猜測。

Molecular motor is a special kind of enzyme protein which is composed of abilities not only accelerating reactions but also working to the surrounding. The energy source is the chemical energy stored in ATP. Conformational changing during the binding and hydrolysis process directly infect the force output and mechanical state, and then, make the work out.
We proposed the concept of irreversibility coupler to explain the irreversibility collected by the molecular motor from the surrounding during the linear non equilibrium thermodynamics binding process. In this article, we make a coarse prediction.

We proposed the molecular motor following the Theory of minimum entropy production rate, therefore, the entropy will be linear to the force loading as it raised linearly. Experimental data is confirmed that the prediction of entropy production rate being steady.

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