本研究中，ZnO/C60/SiO2被合成出來對於X-ray驅動單態氧產生。在X-ray激發後，氧化鋅釋放的綠光被碳六十吸收，經由能量轉移能夠產生單態氧。此外，我們評估氧化鋅綠光螢光受影響在奈米結構的核或殼，藉著設計兩種不同奈米結構ZnO/C60@mSiO2和C60@mSiO2@ZnO。值得注意的是，C60@mSiO2@ZnO奈米結構顯示較好的綠光放光，透露在X-ray觸發產生單態氧的能力，因此預期是有潛能的奈米藥物去做到光動力治療深層腫瘤。然而，從穿透式電子顯微鏡觀察到材料的聚集，且比氧化鋅較差的螢光強度，在未來進一步改善我們的合成參數。

In the present work, ZnO/C60/SiO2 was synthesized for demonstrating the X-ray triggered singlet oxygen generation. Upon X-ray excitation, ZnO emits green luminescence which is absorbed by C60 thereby enabling generation of singlet oxygen by energy transfer mechanism. Further, we proceeded to assess the influence of the position of ZnO, either in the core or shell of the nanostructure on the green luminescence by designing two different nanostructures namely ZnO/C60@mSiO2 and C60@mSiO2@ZnO. Notably, the C60@mSiO2@ZnO nanostructure show better green emission revealing the capability to generate singlet oxygen upon X-ray trigger and thus anticipated to be a potential nanomedicine to accomplish photodynamic therapy in deep seated tumor. However, the aggregation of the nanomaterials as observed from TEM and the inferior fluorescence intensity compared only ZnO to poses a challenge to further improve our synthesis parameter in future.

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