第一部分 自由基反應
1.以醋酸錳(III)和1,4-醌類化合物32及1,3-雙羰基化合物33進行自由基反應，能夠依所使用的反應條件而選擇性獲得異呋喃化合物34及1,4-蒽二酮化合物35。
2.利用醋酸錳(III)、對甲苯磺酸鈉和N-(β-烯丙基碸基丙醯基)-4-甲氧基萘胺化合物65進行自由基環合反應能夠獲得旋環內醯胺化合物75，而完全無六員環(6-endo-trig)的產物。
第二部分 離子性反應
1.利用α-硝基肉桂酸乙酯化合物60和2-硝基乙酸乙酯在鹼性條件下合成多取代基的異噁唑化合物61。此外，利用2-硝基乙酸乙酯和芳香醛59在鹼性條件下亦能單鍋合成異噁唑化合物。單鍋無溶劑條件也成功合成異噁唑醯胺產物82。
2.利用單鍋多組分反應合成多取代基的2,3-二氫呋喃化合物；並探討無溶劑條件的合成方法。

Part 1 Free radical reaction

1.A free radical reaction medicated by manganese(III) acetate between 2-benzoyl-1,4-benzoquiones and 1,3-dicarbonyl compounds produces benzo[c]furan-4,7-diones 34 and anthracene-1,4-diones 35 with chemoselectivity.
2.A free radical cyclization reaction mediated by Mn3+ between TsNa and N-(β-allylsulfonylpropionyl)-4-methoxy- naphthylamine 65 can produce spirolatam 75 without any 6-endo-trig product.

Part 2 Heterolytic reaction

1.Highly functionalized isoxazoles can be synthesized from ethyl α- nitrocinnamates 60 and ethyl nitroacetate under basic condition.Besides, highly functionalized isoxazoles can also be synthesized from ethyl nitroacetate and aromatic aldehydes under basic condition.
3-Amidoisoxazoles 82 can also be synthesized from ethyl nitroacetate， aromatic aldehydes, morpholine and pyridinium bromide under not only one-pot but solvent-free condition.
2.Highly functionalized 2,3-dihydrofurans 34 can be synthesized by one-pot multicomponent reaction. The solvent-free condition is also effective.

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已發表文章
“Free radical reaction between 2-benzoyl-1, 4-benzoquinonesand 1, 3-di- carbonyl compounds”, Chen, K. -P.; Lee, H. -Q.; Cheng, Y. -C.; Chuang, C. -P. Org. Biomol. Chem. 2009, 7, 4074.

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已發表文章
“Ethyl α-nitrocinnamates in the synthesis of highly functionalized isoxazoles”, Chen, K. -P.; Chen, Y. -J.; Chuang, C. -P. Eur. J. Org. Chem. 2010, 5292.

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已發表文章
“N-Phenacylpyridinium bromides in the one-pot synthesis of 2, 3-di- hydrofurans”, Chuang, C. -P.; Chen, K. -P. Tetrahedron 2012, 68, 1401.