The genus Cuscuta belonging to the Convolvulaceae family comprises about 100–170 species spread around the world. Although several species have been studied for their phytochemical characterization and biological activities, there were still many species unexplored to date. The Cuscuta species were reported rich in flavonoids and glycosidic constituents, along with alkaloids, fatty acids, fixed oil, minerals, essential oil, and other phytomolecules. Flavonoids and other molecules of Cuscuta species exhibited various biological activities, for examples, anti-proliferative, antioxidant, anti-inflammatory, hepatoprotective, antimicrobial, and anxiolytic activities, while some other flavonoids were reported for their potential antiviral and anticancer activities especially in ovarian and breast tumor cells.
The present research reviewed all the available data for the twenty different Cuscuta species (C. approximata, C. arvensis, C. australis, C. attenuate, C. campestris, C. chilensis, C. chinensis, C. europaea, C. gronnovii, C. japonica, C. lehmanniana, C. lupuliformis, C. micratha, C. monogyna, C. odorata, C. pedicellata, C. pentagona, C. platyloba, C. racemosa, C. reflexa) mainly on the different types of phytochemical constituents and biological studies. This study was aimed to purify and identify the bioactive principles of C. campestris, and the purification was performed with the assistances of liquid-liquid extraction, column chromatography, and thin-layer chromatography. Totally thirty-one compounds were isolated from the extracts of C. campestris and their structures were identified through the comparison of their physical and spectroscopic data with those published in the literature. Among these, four lignans (+)-pinoresinol (8), piperitol (16), (+)-aptosimon (70), salicifoliol (202), two amides aurantiamide acetate (190) and aurantiamide (193), and one flavonoid kaempferol (9), had already been reported as the potential compounds with significant anti-inflammatory activity in the literature. These experimental results indicated that C. campestris and their constituents are promising candidates for anti-inflammatory drug development for further studies.

1. Story, R., Some plants used by the Bushmen in obtaining food and water. Union of South Africa, Department of Agriculture, Division of Botany, Pretoria, 1958, 30.
2. Yuncker, T. G., The genus Cuscuta. Memoirs of the torrey botanical club. 1932, 18(2), 109, 111, 113-331.
3. Liao, G. I.; Chen, M. Y.; Kuoh, C. S., Cuscuta L. (Convolvulaceae) in Taiwan. Taiwania 2000, 45(3), 226-234.
4. Löffler, C.; Czygan, F. C; Proksch, P., Phenolic constituents as taxonomic markers in the genus Cuscuta (Cuscutaceae). Biochem. Syst. Ecol. 1997, 25(4), 297-303.
5. Lee, M. S.; Chen, C. J; Wan, L.; Koizumi, A.; Chang, W. T.; Yang, M. J.; Lin, W. H.; Tsai, F. J.; Lin, M. K., Quercetin is increased in heat-processed Cuscuta campestris seeds, which enhances the seed’s anti-inflammatory and anti-proliferative activities. Process Biochem. 2011, 46(12), 2248-2254.
6. Behbahani, M., Evaluation of in vitro anticancer activity of Ocimum basilicum, Alhagi maurorum, Calendula officinalis and their parasite Cuscuta campestris. PLoS ONE 2014, 9(12), e116049.
7. Pan, M. H.; Lai, C. S.; Ho, C. T., Anti-inflammatory activity of natural dietary flavonoids. Food Funct. 2010, 1(1), 15-31.
8. Coussens, L. M.; Werb, Z., Inflammation and cancer. Nature 2002, 420(6917), 860-867.
9. Chen, L.; Deng, H.; Cui, H.; Fang, J.; Zuo, Z.; Deng, J.; Li, Y.; Wang, X.; Zhao, L., Inflammatory responses and inflammation-associated diseases in organs. Oncotarget 2018, 9(6), 7204-7218.
10. Malech, H. L.; Gallin, J. I., Current concepts: immunology. Neutrophils in human diseases. N. Engl. J. Med. 1987, 317(11), 687-694.
11. Witko-Sarsat, V.; Rieu, P.; Descamps-Latscha, B.; Lesavre, P.; Halbwachs-Mecarelli, L., Neutrophils: molecules, functions and pathophysiological aspects. Lab. Invest. 2000, 80(5), 617-653.
12. Okajima, K.; Harada, N.; Uchiba, M., Ranitidine reduces ischemia/reperfusion-induced liver injury in rats by inhibiting neutrophil activation. J. Pharmacol. Exp. Ther. 2002, 301(3), 1157-1165.
13. Ennis, M., Neutrophils in asthma pathophysiology. Curr. Allergy Asthma Rep. 2003, 3(2), 159-165.
14. Vinten-Johansen, J., Involvement of neutrophils in the pathogenesis of lethal myocardial reperfusion injury. Cardiovasc. Res. 2004, 61(3), 481-497.
15. Borregaard, N., The human neutrophil. Function and dysfunction. Eur. J. Haematol. 1988, 41(5), 401-413.
16. Roos, D.; van Bruggen, R.; Meischl, C., Oxidative killing of microbes by neutrophils. Microbes Infect. 2003, 5(14), 1307-1315.
17. Masood, I.; Kiani, M. H.; Ahmad, M.; Masood, M. I.; Sadaquat, H., Major contributions towards finding a cure for cancer through chemotherapy: a historical review. Tumori. 2016, 102(1), 6-17.
18. Mirzaei, S. A.; Dinmohammadi, F.; Alizadeh, A.; Elahian, F., Inflammatory pathway interactions and cancer multidrug resistance regulation. Life Sci. 2019, 235, 116825.
19. Nature America Inc., Cancer multidrug resistance. Nat. Biotechnol. 2000, 18, IT18-IT20.
20. Mirzaei, S. A.; Dehkordi, N. G.; Ghamghami, M.; Amiri, A. H.; Abdolahinia, E. D.; Elahian, F., ABC-transporter blockage mediated by xanthotoxin and bergapten is the major pathway for chemosensitization of multidrug-resistant cancer cells. Toxicol. Appl. Pharmacol. 2017, 337, 22-29.
21. Zahreddine, H.; Borden, K. L. B., Mechanisms and insights into drug resistance in cancer. Front. Pharmacol. 2013, 4, 28.
22. Jafari, E.; Bahmanzadegan, A.; Ghanbarian, G.; Rowshan, V., Antioxidant activity and total phenolic content from aerial parts of three Cuscuta species. Anal. Chem. Lett. 2015, 5(6), 377-384.
23. Koca, U.; Küpeli-Akkol, E.; Sekeroglu, N., Evaluation of in vivo and in vitro biological activities of different extracts of Cuscuta arvensis. Nat. Prod. Commun. 2011, 6(10), 1433-1436.
24. Mavlonov, G. T.; Ubaidullaeva, Kh. A.; Kadryaeva, G. V.; Kuznetsova, N. N., Cytotoxic components of Cuscuta. Chem. Nat. Compd. 2008, 44(3), 409-410.
25. Yang, B.; Yang, Q.; Yang, X.; Yan, H. B.; Lu, Q. P., Hyperoside protects human primary melanocytes against H2O2-induced oxidative damage. Mol. Med. Rep. 2016, 13(6), 4613-4619.
26. Agha, A. M.; Sattar, E. A.; Galal, A., Pharmacological study of Cuscuta campestris Yuncker. Phytother. Res. 1996, 10(2), 117-120.
27. Ghule, R. S.; Venkatnarayanan R.; Thakare, S. P.; Jain, H.; Ghule, P. R., Analgesic activity of Cuscuta campestris Yuncker a parasitic plant grown on Nerium indicum Mill. J. Adv. Pharm. Edu. Res. 2011, 1(1), 45-51.
28. Selvi, E. K.; Turumtay, H.; Demir, A.; Turumtay, E. A., Phytochemical profiling and evaluation of the hepatoprotective effect of Cuscuta campestris by high-performance liquid chromatography with diode array detection. Anal. Lett. 2018, 51(10), 1464-1478.
29. Etedali, P.; Behbahani, M.; Rahiminejad, M. R.; Rad, J. S., Effect of crude extracts and fractions of Cuscuta campestris and two different hosts on peripheral blood mononuclear cells and HIV replication. Int. J. Biosci. 2014, 4(9), 83-89.
30. Peng, W. H.; Chen, Y. W.; Lee, M. S.; Chang, W. T.; Tsai, J. C.; Lin, Y. C.; Lin, M. K., Hepatoprotective effect of Cuscuta campestris Yunck. whole plant on carbon tetrachloride induced chronic liver injury in mice. Int. J. Mol. Sci. 2016, 17(12), 2056.
31. Backhouse, N.; Delporte, C.; Negrete, R.; Salinas, P.; Pinto, A.; Aravena, S.; Cassels, B. K., Antiinflammatory and antipyretic activities of Cuscuta chilensis, Cestrum parqui and Psoralea glandulosa. Int. J. Pharmacog. 1996, 34(1), 53-57.
32. Tsai, Y. C.; Lai, W. C.; Du, Y. C.; Wu, S. F.; El-Shazly, M.; Lee, C. L.; Yen, M. H.; Hou, M. F.; Wu, Y. C.; Chang, F. Y., Lignan and flavonoid phytoestrogens from the seed of Cuscuta chinensis. J. Nat. Prod. 2012, 75(7), 1424-1424.
33. Riaz, A.; Rasul, A.; Hussain, G.; Zahoor, M. K.; Jabeen, F.; Subhani, Z.; Younis, T.; Ali, M.; Sarfraz, I.; Selamoglu, Z., Astragalin: a bioactive phytochemical with potential therapeutic activities. Adv. Pharmacol. Sci. 2018, 2018, 9794625.
34. Umehara, K.; Nemoto, K.; Ohkubo, T.; Miyase, T.; Degawa, M.; Noguchi, H., Isolation of a new 15-membered macrocyclic glycolipid lactone, cuscutic resinoside a from the seeds of Cuscuta chinensis: a stimulator of breast cancer cell proliferation. Planta Med. 2004, 704(4), 299-304.
35. Kwon, Y. S.; Chang, B. S.; Kim, C. M., Antioxidative constituents from the seeds of Cuscuta chinensis. Nat. Prod. Sci. 2000, 6(3), 135-138.
36. Yen, F. L.; Wu, T. H.; Lin, L. T.; Lin, C. C., Hepatoprotective and antioxidant effects of Cuscuta chinensis against acetaminophen-induced hepatotoxicity in rats. J. Ethnopharmacol. 2007, 111(1), 123-128.
37. Yen, F. L.; Wu, T. H.; Lin, L. T.; Cham, T. M.; Lin, C. C., Concordance between antioxidant activities and flavonol contents in different extracts and fractions of Cuscuta chinensis. Food Chem. 2008, 108(2), 455-462.
38. Yen, F. L.; Wu, T. H.; Lin, L. T.; Cham, T. M.; Lin, C. C., Nanoparticles formulation of Cuscuta chinensis prevents acetaminophen-induced hepatotoxicity in rats. Food Chem. Toxicol. 2008, 46(5), 1771-1777.
39. Raju, N.; Sakthivel, K. M.; Kannan, N.; Prabhu, V. V.; Guruvayoorappan, C., Cuscuta chinensis ameliorates immunosuppression and urotoxic effect of cyclophosphamide by regulating cytokines - GM-CSF and TNF-Alpha. Appl. Biochem. Biotechnol. 2015, 176(3), 742-757.
40. Liao, J. C.; Chang, W. T.; Lee, M. S.; Chiu, Y. J.; Chao, W. K.; Lin, Y. C.; Lin, M. K.; Peng, W. H., Antinociceptive and anti-inflammatory activities of Cuscuta chinensis seeds in mice. Am. J. Chin. Med. 2014, 42(1), 223-242.
41. Kang, S. Y.; Jung, H. W.; Lee, M. Y.; Lee, H. W.; Chae, S. W.; Park, Y. K., Effect of the semen extract of Cuscuta chinensis on inflammatory responses in LPS-stimulated BV-2 microglia. Chin. J. Nat. Med. 2014, 12(8), 573-581.
42. Yang, L.; Chen, Q.; Wang, F.; Zhang, G., Antiosteoporotic compounds from seeds of Cuscuta chinensis. J. Ethnopharmacol. 2011, 135(2), 553-560.
43. Shin, S.; Lee, Y. J.; Kim, E. J.; Lee, A. S.; Kang, D. G.; Lee, H. S., Effect of Cuscuta chinensis on renal function in ischemia/reperfusion-induced acute renal failure rats. Am. J. Chin. Med. 2011, 39(5), 899-902.
44. Wang, T. J.; An, J.; Chen, X. H.; Deng, Q. D.; Yang, L., Assessment of Cuscuta chinensis seeds′ effect on melanogenesis: comparison of water and ethanol fraction in vitro and in vivo. J. Ethnopharmacol. 2014, 154(1), 240-248.
45. Akbar, S.; Nisa, M.; Tariq, M., CNS depressant activity of Cuscuta chinensis Lam.. Pharm. Biol. (Int. J. Crude Drug Res.) 1985, 23(2), 91-94.
46. Mokhtarifar, N.; Sharif, B.; Naderi, N.; Mosaddegh, M.; Faizi, M., Evaluation of anti-depressant effects of Cuscuta chinensis in experimental models. Res. Pharm. Sci. 2012, 7(5), S826.
47. Yang, H. M.; Shin, H. K.; Kang, Y. H.; Kim, J. K., Cuscuta chinensis extract promotes osteoblast differentiation and mineralization in human osteoblast-like MG-63 cells. J. Med. Food 2009, 12(1), 85-92.
48. Wang, Z.; Fang, J. N.; Ge, D. L.; Li, X. Y., Chemical characterization and immunological activities of an acidic polysaccharide isolated from the seeds of Cuscuta chinensis Lam. Acta Pharmacol. Sin. 2000, 21(12), 1136-1140.
49. Liu, J. H.; Jiang, B.; Bao, Y. M.; An, L. J., Effect of Cuscuta chinensis glycoside on the neuronal differentiation of rat pheochromocytoma PC12 cells. Int. J. Dev. Neuroscience 2003, 21(5), 277-281.
50. Nisa, M.; Akbar, S.; Tariq, M.; Hussain, Z., Effect of Cuscuta chinensis water extract on 7,12-dimethylbenz[α]anthracene-induced skin papillomas and carcinomas in mice. J. Ethnopharmacol. 1986, 18(1), 21-31.
51. Sun, K.; Zhao, C.; Chen, X. F.; Kim, H. K.; Choi, B. R.; Huang, Y. R.; Park, J. K., Ex vivo relaxation effect of Cuscuta chinensis extract on rabbit corpus cavernosum. Asian J. Androl. 2013, 15(1), 134-137.
52. Perveen, S.; Bukhari, I. H.; Ain, Q. U.; Kousar, S.; Rehman, J., Antimicrobial, antioxidant and minerals evaluation of Cuscuta europea and Cuscuta reflexa collected from different hosts and exploring their role as functional attribute. Int. Res. J. Pharm. App. Sci. 2013, 3(5), 43-49.
53. Kakhorova, K. A.; Khashimova, Z. S.; Terenteva, E. O., Studies on cytotoxicity and antioxidant activities of Lectin-like proteins from phytoparasites (Cuscuta europaea). Asian J. Pharm. Pharmacol. 2018, 4(3), 265-270.
54. Abdullah, J. A.; Hammadi, A. A.; Hakem, R.; Hatef, Z; Hussein, N., Study effect of plant extraction for Cuscuta europaea (Dodder) against two species of bacteria Staphylococcus aureus and Escherichia coli. J. Contemp. Med. Sci. 2016, 2(8), 133-137.
55. Stanilova, S. A.; Zhelev, Z. D.; Dobreva, Z. G., Preliminary studies on the immunomodulatory effect of the C3 binding glycoprotein isolated from Cuscuta europea. Int. J. Immunopharmacol. 2000, 22(1), 15-24.
56. Jang, J. Y.; Kim, H. N.; Kim, Y. R.; Choi, Y. H.; Kim, B. W.; Shin, H. K.; Choi, B. T., Aqueous fraction from Cuscuta japonica seed suppresses melanin synthesis through inhibition of the p38 mitogen-activated protein kinase signaling pathway in B16F10 cells. J. Ethnopharmacol. 2012, 141(1), 338-344.
57. Joe, W. A.; Cheon, S. J.; Jang, M. J.; Sung, J. Y.; Jung, S. H.; Kang, B. Y.; Choi, E. Y.; Jeong, Y. S.; Lee, J. S.; Choi, H. J.; Baek, W. J.; An, B. J.; Lee, C. E.; Lee, J. T., Study of the cosmeceutical activities of Cuscuta japonica Choisy. Kor. J. Herbol. 2006, 21(2), 103-108.
58. Mehanna, E. T.; El-sayed, N. M.; Ibrahim, A. K.; Ahmed, S. A.; Abo-Elmatty, D. M., Isolated compounds from Cuscuta pedicellata ameliorate oxidative stress and upregulate expression of some energy regulatory genes in high fat diet induced obesity in rats. Biomed. Pharmacother. 2018, 108, 1253-1258.
59. Zekry, S. H.; Abo-elmatty, D. M.; Zayed, R. A.; Radwan, M. M.; ElSohly, M. A.; Hassanean, H. A.; Ahmed, S. A., Effect of metabolites isolated from Cuscuta pedicellata on high fat diet-fed rats. Med. Chem. Res. 2015, 24(5), 1964-1973.
60. Ali, A.; Haider, M. S.; Hanif, S.; Akhtar, N., Assessment of the antibacterial activity of Cuscuta pedicellata Ledeb. Afr. J. Biotechnol. 2014, 13(3), 430-433.
61. Kimura, Y.; Suzuki, A.; Takematsu, T.; Konnai, M.; Takeuchi, Y., (+)-Abscisic acid and two compounds showing chlorophyll degradation activity in Cuscuta pentagona Engelm. Agric. Biol. Chem. 1982, 46(4), 1071-1074.
62. Ferraz, H. O.; Silva, M. G.; Carvalho, R.; Suffredini, I. B.; Kato, E. T. M.; Arakaki, F.; Bacchi, E. M., Phytochemical study and evaluation of antimicrobial activity and cytotoxicity of Cuscuta racemosa. Rev. Bras. Farmacogn. Braz. J. Pharmacogn. 2011, 21(1), 41-46.
63. Pal, D. K.; Mandal, M.; Senthilkumar, G. P.; Padhiari, A., Antibacterial activity of Cuscuta reflexa stem and Corchorus olitorius seed. Fitoterapia 2006, 77(7-8), 589-591.
64. Raza, M. A.; Mukhtar, F.; Danish, M., Cuscuta reflexa and Carthamus oxyacantha: potent sources of alternative and complimentary drug. SpringerPlus 2015, 4(1), 76.
65. Bais, N.; Kakkar, A.; Mishra, V. K.; Singh, R.; Khare, P., Comparative study on antibacterial activity of ethyl acetate extract of Cuscuta reflexa grown on Cassia fistula and Ficus benghalensis. Int. J. Pharm. Sci. Res. 2014, 5(1), 137-141.
66. Manore, D.; Pillai, S., Joshi, A.; Punashiya, R., Preliminary phytochemical screening and antibacterial activity of ethyl acetate extract of Cuscuta reflexa Roxb. Res. J. Pharm. Tech. 2012, 5(1), 79-82.
67. Kalita, D.; Saikia, J., Ethonomedicinal, antibacterial and antifungal potentiality of Centella asiatica, Nerium indicum and Cuscuta reflexa - widely used in Tiwa Tribe of Morigaon district of Assam, India. Int. J. Phytomed. 2012, 4(3), 380-385.
68. Suresh, V.; Sruthi, V.; Padmaja, B.; Asha, V. V., In vitro anti-inflammatory and anti-cancer activities of Cuscuta reflexa Roxb. J. Ethnopharmacol. 2011, 134(3), 872-877.
69. Udavant, P. B.; Satyanarayana, S. V.; Upasani, C. D., Preliminary screening of Cuscuta reflexa stems for antiinflammatory and cytotoxic activity. Asian Pac. J. Trop. Biomed. 2012, 2(3), S1303-S1307.
70. Riaz, M.; Bilal, A.; Ali, M. S.; Fatima, I.; Faisal, A.; Sherkheli, M. A. and Asghar A., Natural products from Cuscuta reflexa Roxb. with antiproliferation activities in HCT116 colorectal cell lines. Nat. Prod. Res. 2017, 31(5), 583-587.
71. Bhagat, M.; Arora, J. S.; Saxena, A. K., In vitro and in vivo antiproliferative potential of Cuscuta reflexa Roxb. J. Pharm. Res. 2013, 6(7), 690-695.
72. Dokuparthi, S. K.; Banerjee, N.; Kumar, A.; Singamaneni, V.; Giri, A. K; Mukhopadhyay, S., Phytochemical investigation and evaluation of antimutagenic activity of the extract of Cuscuta reflexa Roxb by Ames test. Int. J. Pharm. Sci. Res. 2014, 5(8), 3430-3434.
73. Versiani, M. A.; Kanwal, A.; Faizi, S.; Farooq, A. D., Cytotoxic cardiac glycoside from the parasitic plant Cuscuta reflexa. Chem. Nat. Compd. 2017, 53(5), 915-922.
74. Anis, E.; Anis, I.; Ahmed, S.; Mustafa, G.; Malik, A.; Afza, N.; Abdul Hai, S. M.; Shahzad-Ul-Hussan, S.; Choudhary, M. I., α-Glucosidase inhibitory constituents from Cuscuta reflexa. Chem. Pharm. Bull. 2002, 50(1), 112-114.
75. Tanruean, K.; Poolprasert, P.; Kumla, J.; Suwannarach, N.; Lumyong, S., Bioactive compounds content and their biological properties of acetone extract of Cuscuta reflexa Roxb. grown on various host plants. Nat. Prod. Res. 2019, 33(4), 544-547.
76. Suttuarporn, P.; Tanruean, K., GC-MS analysis, antioxidant and α-glucosidase inhibitory activities of the methanol extract of Cuscuta reflexa Roxb. grown on different hosts. KMUTNB Int. J. Appl. Sci. Technol. 2017, 59-65 (special issue).
77. Azad, A. K.; Laboni, F. R.; Rashid, H.; Ferdous, S.; Rashid, S. S.; Kamal, N.; Labu, Z. K.; Islam, M. S.; Sarker, Z. I., In vitro evaluation of Cuscuta reflexa Roxb. for thrombolytic, antioxidant, membrane stabilizing and antimicrobial activities. Nat. Prod. Res. 2020, 34(16), 2394-2397.
78. Tanruean, K.; Kaewnarin, K.; Suwannarach, N.; Lumyong, S., Comparative evaluation of phytochemicals, and antidiabetic and antioxidant activities of Cuscuta reflexa grown on different hosts in Northern Thailand. Nat. Prod. Commun. 2017, 12(1), 51-54.
79. Nadeem, M.; Mumtaz, M. W.; Danish, M.; Rashid, U.; Mukhtar, H.; Irfan, A.; Anwar, F.; Saari, N., UHPLC-QTOF-MS/MS metabolites profiling and antioxidant/antidiabetic attributes of Cuscuta reflexa grown on Casearia tomentosa: exploring phytochemicals role via molecular docking. Int. J. Food Prop. 2020, 23(1), 918-940.
80. Siddiqui, M. S.; Memon, A. A.; Memon, S.; Baloch, S. G., Cuscuta reflexa as a rich source of bioactive phenolic compounds. J. Herbs Species Med. Plants 2017, 23(2), 157-168.
81. Sandeep; Mittal, A., Evaluation of antimicrobial and antioxidant activity of isolated constituents from areal part of Cuscuta reflexa Roxb. plant. Asian J. Pharm. Clin. Res. 2018, 11(3), 187-190.
82. Sakshy, S.; Kumar, H. kk. S.; Brijesh, T. kr., Comparative antioxidant activity of Cuscuta reflexa and Cassytha filiformis. J. Pharm. Res. 2012, 5(1), 441-443.
83. Ramya, B.; Natarajan, E.; Vijikumar, S.; John vasanth., J.; Muthukkumarasamy, S.; Muthuramsanjivi, V. K. A., Isolation and characterization of bioactive metabolites in Cuscuta reflexa Roxb. Indian J. Nat. Sci. 2010, 1(2), 134-139.
84. Uddin, S. J.; Shilpi, J. A.; Middleton, M.; Byres, M.; Shoeb, M.; Nahar, L.; Sarker, S. D., Swarnalin and cis-swarnalin, two new tetrahydrofuran derivatives with free radical scavenging activity, from the aerial parts of Cuscuta reflexa. Nat. Prod. Res. 2007, 21(7), 663-668.
85. Yadav, S. B.; Tripathi, V.; Singh, R. K.; Pandey, H. P., Antioxidant activity of Cuscuta reflexa stems. Indian J. Pharma. Sci. 2000, 62(6), 477-478.
86. Anjum, F.; Bukhari, S. A.; Shahid, M.; Bokhari, T. H.; Talpur, M. M. A., Exploration of nutraceutical potential of herbal oil formulated from parasitic plant. Afr. J. Tradit. Complement. Altern. Med. 2014, 11(1), 78-86.
87. Inamdar, F. B.; Oswal, R. J.; Chorage, T. V.; Garje, K., In vitro antimicrobial activity of Cuscuta reflexa Roxb. Int. Res. J. Pharm. 2011, 2(4), 214-216.
88. Manirujjaman; Suchana, S.; Collet, T.; Nawshin, L. N.; Chowdhury, M. A. R., Antimicrobial effects of ethanolic extracts from Cuscuta reflexa Roxb. (Convolvulaceae). Int. J. Pharmacogn. Phytochem. Res. 2016, 8(6), 930-932.
89. Chatterjee, D.; Sahu, R. K.; Jha, A. K.; Dwivedi, J., Evaluation of antitumor activity of Cuscuta reflexa Roxb (Cuscutaceae) against Ehrlich ascites carcinoma in Swiss albino mice. Trop. J. Pharm. Res. 2011, 10(4), 447-454.
90. Mostofa, R.; Begum, R.; Wang, H.; Begum, Mst. M.; Karim, R.; Begum, T.; Siddiquee, N. A.; Sultana, R.; Sultana, S., Kabir, A. K. L.; Alam, S.; Nova, T. T., Promising antidiabetic potential of Cuscuta reflexa leaves methanol extract in alloxan-induced diabetic rats. Clin. Phytosci. 2020, 6(1), 26.
91. Rath, D.; Kar, D. M.; Panigrahi, S. K.; Maharana, L., Antidiabetic effects of Cuscuta reflexa Roxb. in streptozotocin induced diabetic rats. J. Ethnopharmacol. 2016, 192, 442-449.
92. Adnan, Md.; Nazim Uddin Chy, Md.; Mostafa Kamal, A. T. M.; Riad Chowdhury, Md.; Shariful Islam, Md.; Amzad Hossain, Md.; Tareq, A. M.; Imam Hossain Bhuiyan, Md.; Nasim Uddin, Md.; Tahamina, A.; Obyedul Kalam Azad, Md.; Lim, Y. S.; Cho, D. H., Unveiling pharmacological responses and potential targets insights of identified bioactive constituents of Cuscuta reflexa Roxb. leaves through in vivo and in silico approaches. Pharmaceuticals 2020, 13(3), 50.
93. Patel, S.; Sharma, V.; Chauhan, N. S.; Dixit, V. K., A study on the extracts of Cuscuta reflexa Roxb. in treatment of cyclophosphamide induced alopecia. DARU Journal of Pharmaceutical Sciences 2014, 22(1), 7.
94. Katiyar, N. S.; Singh, A. P.; Gangwar, A. K.; Rao, N. V., Evaluation of hepatoprotective activity of stem extracts of Cuscuta reflexa (Roxb) in rats. Int. J. Pharm. Pharm. Sci. 2015, 7(6), 231-234.
95. Amaresh, P.; Seemanchala, R.; Debashis, P.; Arpan, M.; Kumar, G. B.; Nath, B. N., Hepatoprotective activity of whole part of the plant Cuscuta reflexa Roxb. (Convolvulaceae) in chloroform, ethanol and paracetamol induced hepatotoxic rat models. Int. J. Pharm. Clin. Res. 2014, 6(2), 127-132.
96. Borole, S. P.; Oswal, R. J.; Antre, R. V.; Kshirsagar, S. S.; Bagul, Y. R., Evaluation of anti-epileptic activity of Cuscuta reflexa Roxb. Res. J. Pharm. Biol. Chem. Sci. 2011, 2(1), 657-663.
97. Rahmatullah, M.; Sultan, S.; Toma, T. T.; Lucky, S.-a-S.; Chowdhury, M. H.; Haque, W. M.; Annay, E. A.; Jahan, R., Effect of Cuscuta reflexa stem and Calotropis procera leaf extracts on glucose tolerance in glucose-induced hyperglycemic rats and mice. Aft. J. Tradit. Complement. Altern. Med. 2010, 7(2), 109-112.
98. Bhattacharya, S.; Roy, B., Preliminary investigation on antipyretic activity of Cuscuta reflexa in rats. J. Adv. Pharm. Technol. Res. 2010, 1(1), 83-87.
99. Pandit, S.; Chauhan, N. S.; Dixit, V. K., Effect of Cuscuta reflexa Roxb on androgen-induced alopecia. J. Cosmet. Dermatol. 2008, 7(3), 199-204.
100. Gupta, M.; Mazumder, U. K.; Pal, D.; Bhattacharya, S.; Chakrabarty, S., Studies on brain biogenic amines in methanolic extract of Cuscuta reflexa Roxb. and Corchorus olitorius Linn. seed treated mice. Acta Pol. Pharm. 2003, 60(3), 207-210.
101. Pal. D.; Panda, C.; Sinhababu, S.; Dutta, A.; Bhattacharya, S., Evaluation of psychopharmacological effects of petroleum ether extract of Cuscuta reflexa Roxb. stem in mice. Acta Pol. Pharm. 2003, 60(6), 481-486.
102. Mahmood, N.; Piacente, S.; Burke, A.; Khan, A.; Pizza, C., Constituents of Cuscuta reflexa are anti-HIV agents. Antivir. Chem. Chemother. 1997, 8(1), 70-74.
103. Gilani, A. H.; Aftab, K., Pharmacological actions of Cuscuta reflexa. Int. J. Pharmacog. 1992, 30(4), 296-302.
104. Jagtap, M. D.; Asabe, A. S.; Telave, A. B.; Mali, B. S.; Chavan, S. J.; Kanade, M. B, Antifungal potential of Cuscuta reflexa Roxb. Cent. Euro. J. Exp. Bio. 2014, 3(3), 30-32.
105. Ali, S. R.; Haque, S.; Mudassar; Versiani, M. A.; Faizi, S.; Farooq, A. D., Cytotoxicity and chromosomal aberrations induced by methanolic extract of Cuscuta reflexa and its pure compounds on meristematic cells of Allium species. Pak. J. Pharm. Sci. 2017, 30(2), 521-529.
106. Mala, F. A.; Sofi, M. A., Evaluation of antihistaminic activity of herbal drug isolated from Cuscuta reflexa Roxb. Ann. Plant Sci. 2017, 6(11), 1807-1810.
107. Alamgeer; Niazi, S. G.; Uttra, A. M.; Qaiser, M. N.; Ahsan, H., Appraisal of anti-arthritic and nephroprotective potential of Cuscuta reflexa. Pharm. Biol. 2017, 55(1), 792-798.
108. Bhan, S.; Mohan, L.; Srivastava, C. N., Efficacy of Cuscuta reflexa extract and its synergistic activity with temephos against mosquito larvae. Int. J. Mosquito Res. 2015, 2(1), 34-41.
109. Akter, H.; Akter, H.; Rahmatullah, M., Synergistic antihyperglycemic activity of Coccinia grandis leaves and Cuscuta reflexa stems. World J. Pharm. Pharm. Sci. 2016, 5(12), 236-243.
110. Ye, M.; Li, Y.; Yan, Y.; Liu, H.; Ji, X., Determination of flavonoids in Semen cuscutae by RP-HPLC. J. Pharm. Biomed. Anal. 2002, 28(3-4), 621-628.
111. Ye, M.; Yan, Y.; Guo, D. A., Characterization of phenolic compounds in the Chinese herbal drug Tu-Si-Zi by liquid chromatography coupled to electrospray ionization mass spectrometry. Rapid Commun. Mass Spectrom. 2005, 19(11), 1469-1484.
112. He, X.; Yang, W.; Ye, M.; Wang, Q.; Guo, D., Differentiation of Cuscuta chinensis and Cuscuta australis by HPLC-DAD-MS analysis and HPLC-UV quantitation. Planta Med. 2011, 77(17), 1950-1957.
113. Rho, T.; Yoon, K. D., Application of off-line two-dimensional high-performance countercurrent chromatography on the chloroform-soluble extract of Cuscuta auralis seeds. J. Sep. Sci. 2018, 41(10), 2169-2177.
114. Du, X. M.; Sun, N. Y.; Nishi, M.; Kawasaki, T.; Guo, Y. T.; Miyahara, K., Components of the ether-insoluble resin glycoside fraction from the seed of Cuscuta australis. J. Nat. Prod. 1999, 62(5), 722-725.
115. Garcia, R.; Erazo, S.; Peña, R. C., Flavonoids and alkaloids from Cuscuta (Cuscutaceae). Biochem. Syst. Ecol. 1995, 23(5), 571-572.
116. Yahara, S.; Domoto, H.; Sugimura, C.; Nohara, T.; NiiHo, Y.; Nakajima, Y.; Ito, H., An alkaloid and two lignans from Cuscuta chinensis. Phytochemistry 1994, 37(6), 1755-1758.
117. Pan, S.; Wang, X.; Duan, W.; Yu, Z.; Zhang, L.; Liu, W., Preparative isolation and purification of flavonoids from Cuscuta chinesis Lam. by high-speed countercurrent chromatography. J. Liq. Chromatogr. Relat. Technol. 2014, 37(15), 2162-2171.
118. Wang, J.; Tan, D.; Wei, G.; Guo, Y.; Chen, C.; Zhu, H.; Xue, Y.; Yin, C.; Zhang, Y., Studies on the chemical constituents of Cuscuta chinensis. Chem. Nat. Compd. 2016, 52(6), 1133-1136.
119. Shekarchi, M.; Kondori, B. M.; Hajimehdipoor, H.; Abdi, L.; Naseri, M.; Pourfarzib, M.; Amin, G., Finger printing and quantitative analysis of Cuscuta chinensis flavonoid contents from different hosts by RP-HPLC. Food Nutri. Sci. 2014, 5(10), 914-921.
120. Hajimehdipoor, H.; Kondori, B. M.; Amin, G. R.; Adib, N.; Rastegar, H.; Shekarchi, M., Development of a validated HPLC method for the simultaneous determination of flavonoids in Cuscuta chinensis Lam. by ultra-violet detection. DARU Journal of Pharmaceutical Sciences 2012, 20(1), 57-62.
121. Yang, W. Z.; Qiao, X.; Bo, T.; Wang, Q.; Guo, D. A.; Ye, M., Low energy induced homolytic fragmentation of flavonol 3-O-glycosides by negative electrospray ionization tandem mass spectrometry. Rapid Commun. Mass Spectrom. 2014, 28(4), 385-395.
122. He, X. H.; Yang, W. Z.; Meng, A. H.; He, W. N.; Guo, D. A.; Ye, M., Two new lignan glucosides from the seeds of Cuscuta chinensis. J. Asian Nat. Prod. Res. 2010, 12(11), 934-939.
123. Du, X. M.; Kohinata, K.; Kawasaki, T.; Guo, Y. T.; Miyahara, K., Components of the ether-insoluble resin glycoside-like fraction from Cuscuta chinensis. Phytochemistry 1998, 48(5), 843-850.
124. Xiang, S. X.; He, Z. S; Ye, Y., Furofuran lignans from Cuscuta chinensis. Chin. J. Chem. 2001, 19(3), 282-285.
125. Miyahara, K.; Du, X. M; Watanabe, M.; Sugimura, C.; Yahara, S.; Nohara, T., Resin glycoside. XXIII. Two novel acylated trisaccharides related to resin glycoside from the seeds of Cuscuta chinensis. Chem. Pharm. Bull. 1996, 44(3), 481-485.
126. Kamilov, Kh. M.; Nikonov, G. K., Esters of Cuscuta lehmanniana. Chem. Nat. Compd. 1977, 13(1), 99-100.
127. Löffler, C.; Sahm, A.; Wray, V.; Czygan, F. C.; Proksch, P., Soluble phenolic constituents from Cuscuta reflexa and Cuscuta platyloba. Biochem. Syst. Ecol. 1995, 23(2), 121-128.
128. Sousa, A. L.; Sales, Q. S.; Braz-Filho, R.; de Oliveira, R. R., Lignans and flavonoids isolated from Cuscuta racemosa Mart. & Humb (Convolvulaceae) by droplet counter-current chromatography. J. Liq. Chromatogr. Relat. Technol. 2012, 35(16), 2294-2303.
129. Bacchi, E. M., Flavonoids from Cuscuta racemosa. Planta Med. 1993, 59(S1), A605.
130. Shailajan, S.; Joshi, H., Optimized separation and quantification of pharmacologically active markers quercetin, kaempferol, β-sitosterol and lupeol from Cuscuta reflexa Roxb. J. Pharm. Res. 2011, 4(6), 1851-1853.
131. Chatterjee, D.; Sahu, R. K., Chemical characterization of the flavonoid constituents of Cuscuta reflexa. UK J. Pharm. Biosci. 2014, 2(3), 13-16.
132. Faizi, S.; Versiani, M. A.; Kanwal, A.; Naz, A., Host-plant effect on the chemical constituents of Cuscuta reflexa. Chem. Nat. Compd. 2017, 53(3), 540-542.
133. Shailajan, S.; Menon, S.; Joshi, H., Microwave-assisted extraction of lupeol from Cuscuta reflexa Roxb. growing on different hosts and its quantitation by high-performance thin layer chromatography. Int. J. Green Pharm. 2011, 5(3), 212-215.
134. Anis, E.; Mustafa, G.; Ahmed, S.; Nisarullah; Malik, A.; Afza, N.; Badar, Y., Sterols and sterol glycosides from Cuscuta reflexa. Nat. Prod. Res. 1999, 5(3), 124-126.
135. Sandeep; Mittal, A., Isolation and characterization of constituents from areal part of Cuscuta reflexa Roxb. Adv. Biores. 2017, 8(2), 250-254.
136. Tripathi, V. J.; Yadav, S. B.; Upadhyay, A. K., A new flavanone, reflexin, from Cuscuta reflexa and its selective sensing of nitric oxide. Appl. Biochem. Biotechnol. 2005, 127(1), 63-67.
137. Jung, H. W.; Mahesh, R.; Lee, J. G.; Lee, S. H.; Kim, Y. S.; Park, Y. K., Pinoresinol from the fruits of Forsythia koreana inhibits inflammatory responses in LPS-activated microglia. Neurosci. Lett. 2010, 480(3), 215-220.
138. Gabaston, J.; Richard, T.; Cluzet, S.; Pinto, A. P.; Dufour, M. C.; Corio-Costet, M. F.; Mérillon, J. M., Pinus pinaster Knot: a source of polyphenols against Plasmopara viticola. J. Agric. Food Chem. 2017, 65(40), 8884-8891.
139. Chang, Y. C.; Chang, F. R.; Wu, Y. C., The constituents of Lindera glauca. J. Chin. Chem. Soc. 2000, 47(2), 373-380.
140. Okuyama, E.; Suzumura, K.; Yamazaki, M., Pharmacologically active components of Todopon puok (Fagraea racemosa), a medicinal plant from Borneo. Chem. Pharm. Bull. 1995, 43(12), 2200-2204.
141. Rahman, M. M. A; Dewick, P. M.; Jackson, D. E.; Lucas, J. A., Lignans of Forsythia intermedia. Phytochemistry 1990, 29(6), 1971-1980.
142. Nishibe, S.; Tsukamoto, H.; Hisada, S., Effects of O-methylation and O-glucosylation on carbon-13 nuclear magnetic resonance chemical shifts of matairesinol, (+)-pinoresinol and (+)-epipinoresinol. Chem. Pharm. Bull. 1984, 32(11), 4653-4657.
143. Dellagreca, M.; Monaco, P.; Pinto, G.; Pollio, A.; Previtera, L.; Temussi, F., Phytotoxicity of low-molecular-weight phenols from olive mill waste waters. Bull. Environ. Contam. Toxicol. 2001, 67(3), 352-359.
144. Chiang, Y. M.; Liu, H. K.; Lo, J. M.; Chien, S. C.; Chan, Y. F.; Lee, T. H.; Su, J. K.; Kuo, Y. H., Cytotoxic constituents of leaves of Calocedrus formosana. J. Chin. Chem. Soc. 2003, 50(1), 161-166.
145. Han, T.; Li, H.; Zhang, Q.; Zheng, H.; Qin, L., New thiazinediones and other components from Xanthium strumarium. Chem. Nat. Compd. 2006, 42(5), 567-570.
146. Chen, C. Y.; Chang, F. R.; Teng, C. M.; Wu, Y. C., Cheritamine, a new N-fatty tryptamine and other constituents from the stems of Annona cherimola. J. Chin. Chem. Soc. 1999, 46(1), 77-86.
147. Georgousaki, K.; Tsafantakis, N.; Gumeni, S.; Lambrinidis, G.; González-Menéndez, V.; Tormo, J. R.; Genilloud, O.; Trougakos, I.; Fokialakis, N., Biological evaluation and in silico study of benzoic acid derivatives from Bjerkandera adusta targeting proteostasis network modules. Molecules 2020, 25(3), 666.
148. Xin, X. L.; Aisa, H. A.; Wang, H. Q., Flavonoids and phenolic compounds from seeds of the Chinese plant Nigella glandulifera. Chem. Nat. Compd. 2008, 44(3), 368-369.
149. Chung, C. P.; Hsia, S. M.; Lee, M. Y.; Chen, H. J.; Cheng, F.; Chan, L. C.; Kuo, Y. H.; Lin, Y. L.; Chiang, W., Gastroprotective activities of adlay (Coix lachryma-jobi L. var. ma-yuen Stapf) on the growth of the stomach cancer AGS cell line and indomethacin-induced gastric ulcers. J. Agric. Food Chem. 2011, 59(11), 6025-6033.
150. Ho, V. B.; Trinh, T. T. V.; Vu, V. C.; Nguyen, T. H.; Pham, T. H.; Nguyen, L. T.; Nguyen, X. N.; Pham, V. C.; Nguyen, Q. V., Lignans from leaves of Amesiodendron chinense and their cytotoxic activity. Vietnam J. Sci. Technol. 2020, 58(4), 442-449.
151. Yamauchi, S.; Yamaguchi, M., Synthesis of (+)-aptosimon, a 4-oxofurofuran lignan, by erythro selective aldol condensation and stereoconvergent cyclization as the key reactions. Biosci. Biotechnol. Biochem. 2003, 67(4), 838-846.
152. Xin, X. L.; Aisa, H. A.; Wang, H. Q., Flavonoids and phenolic compounds from seeds of the Chinense plant Nigella glandulifera. Chem. Nat. Compd. 2008, 44(3), 294-295.
153. Ahmad, F.; Ali, M.; Alam, P., New phytoconstituents from the stem bark of Tinospora cordifolia Miers. Nat. Prod. Res. 2010, 24(10), 926-934.
154. Kuo, Y. H.; Li, Y. C., Constituents of the bark of Ficus microcarpa L.f. J. Chin. Chem. Soc. 1997, 44(3), 321-325.
155. Umbetova, A. K.; Choudhary, M. I.; Sultanova, N. A.; Burasheva, G. S.; Abilov, Z. A., Triterpenoids from plants of the genus Tamarix. Chem. Nat. Compd. 2006, 42(3), 332-335.
156. Bibi, N.; Tanoli, S. A. K.; Farheen, S.; Afza, N.; Siddiqi, S.; Zhang, Y.; Kazmi, S. U.; Malik, A., In vitro antituberculosis activities of the constituents isolated from Haloxylon salicornicum. Bioorg. Med. Chem. Lett. 2010, 20(14), 4173-4176.
157. Rani, S.; Khan, S. A.; Ali, M., Phytochemical investigation of the seeds of Althea officinalis L. Nat. Prod. Res. 2010, 24(14), 1358-1364.
158. Chen, Z.; Liu, Y. M.; Yang, S.; Song, B. A.; Xu, G. F.; Bhadury, P. S.; Jin, L. H.; Hu, D. Y.; Liu, F.; Xue, W.; Zhou, X., Studies on the chemical constituents and anticancer activity of Saxifraga stolonifera (L) Meeb. Bioorg. Med. Chem. 2007, 16(3), 1337-1344.
159. Kodaira, H.; Ishikawa, M.; Komoda, Y.; Nakajima, T., Isolation and identification of anti-platelet aggregation principles from the bark of Fraxinus japonica Blume. Chem. Pharm. Bull. 1983, 31(7), 2262-2268.
160. Nishina, A.; Hasegawa, K. I.; Uchibori, T.; Seino, H.; Osawa, T., 2,6-Dimethoxy-p-benzoquinone as an antibacterial substance in the bark of Phyllostachys heterocycla var. Pubescens, a species of thick-stemmed bamboo. J. Agric. Food Chem. 1991, 39(2), 266-269.
161. Peng, W.; Han, T.; Wang, Y.; Xin, W. B.; Zheng, C. J.; Qin, L. P., Chemical constituents of the aerial part of Atractylodes macrocephala. Chem. Nat. Compd. 2011, 46(6), 959-960.
162. Nwodo, N. J.; Okoye, F. B. C.; Lai, D.; Debbab, A.; Brun, R.; Proksch, P., Two trypanocidal dipeptides from the roots of Zapoteca portoricensis (Fabaceae). Molecules 2014, 19(5), 5470-5477.
163. Serra, S.; Barakat, A.; Fuganti, C., Chemoenzymatic resolution of cis- and trans-3,6-dihydroxy-α-ionone. Synthesis of the enantiomeric forms of dehydrovomifoliol and 8,9-dehydrotheaspirone. Tetrahedron Asymmetry 2007, 18(21), 2573-2580.
164. Xiong, H. P.; Mi, J. L.; Le, J. M.; Wu, Z. J.; Chen, W. S., Chemical constituents of Ampelopsis japonica. Chem. Nat. Compd. 2017, 53(4), 701-793.
165. Schievano, E.; Morelato, E.; Facchin, C.; Mammi, S., Characterization of markers of botanical origin and other compounds extracted from unifloral honeys. J. Agric. Food Chem. 2013, 61(8), 1747-1755.
166. Jiang, M.; Zhang, W.; Yang, X.; Xiu, F.; Xu, H.; Ying, X.; Stien, D., An isoindole alkaloid from Portulaca oleracea L. Nat. Prod. Res. 2018, 32(20), 2431-2436.
167. Banerji, A.; Ray, R., Aurantianmides: a new class of modified dipeptides from Piper aurantiacum. Phytochemistry 1981, 20(9), 2217-2220.
168. Dosumu, O. O.; Onocha, P.; Ekundayo, O.; Ali, M., Isolation of aurantiamides from Gomphrena celosioides C. Mart. Iran. J. Pharm. Res. 2014, 13(1), 143-147.
169. Xu, B.; Huang, Z.; Liu, C.; Cai, Z.; Pan, W.; Cao, P.; Hao, X.; Liang, G., Synthesis and anti-hepatitis B virus activities of Matijing-Su derivatives. Bioorg. Med. Chem. 2009, 17(8), 3118-3125.
170. Hui, Y.; Zhou, X. Q.; Chen, G. Y.; Han, C. R.; Song, X. P.; Dai, C. Y.; Chen, W. H., Chemical constituents of the flower of Wedelia trilobata. Chem. Nat. Compd. 2019, 55(1), 160-163.
171. Jia, L.; Li, D.; Jing, L. L.; Guo, M. M., Studies on the chemical constituents from petroleum ether portion of Abelmoschus esculentus. J. Chin. Med. Mat. ( Zhongyaocai ) 2010, 33(8), 1262-1265.
172. Kimura, Y.; Akihisa, T.; Yasukawa, K.; Takido, M.; Tamura, T., Structures of five hydroxylated sterols from the seeds of Trichosanthes kirilowii Maxim. Chem. Pharm. Bull. 1995, 43(10), 1813-1817.
173. Wang, H.; Cong, W. L.; Fu, Z. L.; Chen, D. F.; Wang, Q., Anti-complementary constituents of Viola kunawarensis. Nat. Prod. Res. 2017, 31(19), 2312-2315.
174. Elmaidomy, A. H.; Mohammed, R.; Hassan, H. M.; Owis, A. I.; Rateb, M. E.; Khanfar, M. A.; Krischke, M.; Mueller, M. J.; Abdelmohsen, U. R., Metabolomic profiling and cytotoxic tetrahydrofurofuran lignans investigations from Premna odorata Blanco. Metabolites 2019, 9(10), 223.
175. Cantrell, C. L.; Schrader, K. K.; Mamonov, L. K.; Sitpaeva, G. T.; Kustova, T. S.; Dunbar, C.; Wedge, D. E., Isolation and identification of antifungal and antialgal alkaloids from Haplophyllum sieversii. J. Agric. Food Chem. 2005, 53(20), 7741-7748.
176. Miyazawa, M.; Kasahara, H.; Kameoka, H., Biotransformation of lignans: a specific microbial oxidation of (+)-eudesmin and (+)-magnolin by Aspergillus niger. Phytochemistry 1993, 34(6), 1501-1507.
177. Latip, J.; Hartley, T. G.; Waterman, P. G., Lignans and coumarins metabolites from Melicope hayesii. Phytochemistry 1999, 51(1), 107-110.
178. Nguyen, T. M. P.; Trinh, T. C.; Dang, N. Q., Anti-inflammatory activity of methyl ferulate isolated from Stemona tuberosa Lour. Asian Pac. J. Trop. Med. 2014, 7(Suppl 1), S327-S331.
179. Bazin, M. A.; Kihel, L. E.; Jouanne, M.; Lancelot, J. C.; Rault, S., Synthesis of new avenalumic carboxamide derivatives in the ferulic series. Synth. Commun. 2008, 38(22), 3947-3959.
180. Zhang, X.; Geoffroy, P.; Miesch, M.; Julien-David, D.; Raul, F.; Aoudé-Werner, D.; Marchioni, E., Gram-scale chromatographic purification of β-sitosterol. Synthesis and characterization of β-sitosterol oxides. Steroids 2005, 70(13), 886-895.
181. Zhao, J.; Mück-Lichtenfeld, C.; Studer, A., Cooperative N-heterocyclic carbene (NHC) and ruthenium redox catalysis: oxidative esterification of aldehydes with air as the terminal oxidant. Adv. Synth. Catal. 2013, 355(6), 1098-1106.
182. Kuo, P. C.; Hung, H. Y.; Nian, C. W.; Hwang, T. L.; Cheng, J. C.; Kuo, D. H.; Lee, E. J.; Tai, S. H.; Wu, T. S., Chemical constituents and anti-inflammatory principles from the fruits of Forsythia suspensa. J. Nat. Prod. 2017, 80(4), 1055-1064.
183. González, A. G.; Estévez-Reyes, R.; Mato, C., Salicifoliol, a new furolactone-type lignan from Bupleurum salicifolium. J. Nat. Prod. 1989, 52(5), 1139-1142.
184. Aguiar, R. M.; Alves, C. Q.; David, J. M; de Rezende, L. C.; Lima, L. S.; David, J. P.; de Queiróz, L. P., Antioxidant activities of isolated compounds from stems of Mimosa invisa Mart. ex Colla. Quim. Nova 2012, 35(3), 567-570.
185. Woo, S. Y.; Wong, C. P.; Win, N. N.; Lae, K. Z. W.; Woo, B.; Elsabbagh, S. A.; Liu, Q. Q.; Ngwe, H.; Morita, H., Anti-melanin deposition activity and active constituents of Jatropha multifida stems. J. Nat. Med. 2019, 73(4), 805-813.
186. Zhang, W.; Wang, Y.; Geng, Z.; Guo, S.; Cao, J.; Zhang, Z.; Pang, X.; Chen, Z.; Du, S.; Deng, Z., Antifeedant activities of lignans from stem bark of Zanthoxylum armatum DC. against Triblium castaneum. Molecules 2018, 23(3), 617.
187. Marchand, P. A.; Zajicek, J.; Lewis, N. G., Oxygen insertion in Sesamum indicum furanofuran lignans. Diastereoselective syntheses of enzyme substrate analogues. Can. J. Chem. 1997, 75(6), 840-849.
188. Saladino, R.; Fiani, C.; Crestini, C.; Argyropoulos, D. S.; Marini, S.; Coletta, M., An efficient and stereoselective dearylation of asarinin and sesamin tetrahydrofurofuran lignans to acuminatolide by methyltrioxorhenium/H2O2 and UHP systems. J. Nat. Prod. 2007, 70(1), 39-42.
189. Deyama, T.; Ikawa, T.; Nishibe, S., The constituents of Eucommia ulmoides Oliv. II. Isolation and structures of three new lignan glycosides. Chem. Pharm. Bull. 1985, 33(9), 3651-3657.
190. Lee, C. K.; Lu, C. K.; Kuo, Y. H.; Chen, J. Z.; Sun, G. Z., New prenylated flavones from the roots of Ficus beecheyana. J. Chin. Chem. Soc. 2004, 51(2), 437-441.
191. Wei, J.; Zhang, X. Y.; Deng, S.; Cao, L.; Xue, Q. H.; Gao, J. M., α-Glucosidase inhibitors and phytotoxins from Streptomyces xanhthophaeus. Nat. Prod. Res. 2017, 31(17), 2062-2066.
192. Karakousi, C. V.; Gabrieli, C.; Kokkalou, E., Chemical composition and biological activities of Indigofera hirsuta aerial parts′ methanol fractions. Nat. Prod. Res. 2020, 34(4), 558-562.
193. Zhang, J.; Chen, J.; Liang, Z.; Zhao, C., New lignans and their biological activities. Chem. Biodivers. 2014, 11(1), 1-54.
194. During, A.; Debouche, C.; Raas, T.; Larondelle, Y., Among plant lignans, pinoresinol has the strongest antiinflammatory properties in human intestinal Caco-2 cells. J. Nutr. 2012, 142(10), 1798-1805.
195. López-Biedma, A.; Sánchez-Quesada, C.; Beltrán, G.; Delgado-Rodríguez, M.; Gaforio, J. J., Phytoestrogen (+)-pinoresinol exerts antitumor activity in breast cancer cells with different oestrogen receptor statuses. BMC Complement. Altern. Med. 2016, 16(1), 350.
196. Tran, H. Q.; Nguyen, T. T. N.; Chau, V. M.; Phan, V. K.; Bui, H. T.; Nguyen, P. T.; Song, S. B.; Kim, Y. H., Anti-inflammatory and PPAR transactivational effects of secondary metabolites from the roots of Asarum sieboldii. Bioorg. Med. Chem. Lett. 2012, 22(7), 2527-2533.
197. Sánchez, L. A.; Olmedo, D.; López-Pérez, J. L.; Williams, T. D.; Gupta, M. P., Two new alkylresorcinols from Homalomena wendlandii and their cytotoxic activity. Nat. Prod. Commun. 2012, 7(8), 1043-1046.
198. Cao, T. Q.; Tran, M. H.; Kim, J. A.; Tran, P. T.; Lee, J. H.; Woo, M. H.; Lee, H. K.; Min, B. S., Inhibitory effects of compounds from Styrax obassia on NO production. Bioorg. Med. Chem. Lett. 2015, 25(22), 5087-5091.
199. Chen, L.; Liu, Y.; Jia, D.; Yang, J.; Zhao, J.; Chen, C.; Liu, H.; Liang, X., Pharmacokinetics and biodistribution of aurantiamide and aurantiamide acetate in rats after oral administration of Portulaca oleracea L. extracts. J. Agric. Food Chem. 2016, 64(17), 3445-3455.
200. Li, W. T.; Yang, B. X.; Zhu, W.; Gong, M. H.; Xu, X. D.; Lu, X. H.; Sun, L. L.; Tian, J. K.; Zhang, L., A new indole alkaloidal glucoside from the aerial parts of Clematis terniflora DC. Nat. Prod. Res. 2013, 27(24), 2333-2337.
201. Yang, Y.; Zhang, L. H.; Yang, B. X.; Tian, J. K.; Zhang, L., Aurantiamide acetate suppresses the growth of malignant gliomas in vitro and in vivo by inhibiting autophagic flux. J. Cell. Mol. Med. 2015, 19(5), 1055-1064.
202. Zhou, B.; Yang, Z.; Feng, Q.; Liang, X.; Li, J.; Zanin, M.; Jiang, Z.; Zhong, N., Aurantiamide acetate from Baphicacanthus cusia root exhibits anti-inflammatory and anti-viral effects via inhibition of the NF-κB signaling pathway in influenza A virus-infected cells. J. Ethnopharmacol. 2017, 199, 60-67.
203. Ogunmoyole, T.; Olalekan, O. O.; Fatai, O.; Makun, J. O.; Kade, I. J., Antioxidant and phytochemical profile of aqueous and ethanolic extract of Garcinia kola. J. Pharmacog. Phytother. 2012, 4(5), 66-74.
204. Kumar, S.; Pandey, A. K., Chemistry and biological activities of flavonoids: an overview. Sci. World J. 2013, 2013, 162750.
205. Guo, P.; Feng, Y. Y., Anti-inflammatory effects of kaempferol, myricetin, fisetin and ibuprofen in neonatal rats. Trop. J. Pharm. Res. 2017, 16(8), 1819-1826.
206. Nguyen, T. T. T.; Tran, E.; Ong, C. K.; Lee, S. K.; Do, P. T.; Huynh, T. T.; Nguyen, T. H.; Lee, J. J.; Tan, Y.; Ong, C. S.; Huynh, H., Kaempferol-induced growth inhibition and apoptosis in A549 lung cancer cells is mediated by activation of MEK-MAPK. J. Cell. Physiol. 2003, 197(1), 110-121.