在本研究中我們利用派屈網(Petri net)發展出系統化建模策略來描述原核生物中包含基因控制機構的生化反應系統之行為。我們首先建構了不同的單元模組來表示細胞中的單元功能，再逐步依層級式結構將之組合而成系統模式。我們利用了幾個虛擬案例來展示了此一模式的用途，並利用四組文獻數據來驗證其正確性，並進一步預測反應系統的動態行為。

　　A systematic strategy is developed in the present study to model biological reaction networks in prokaryotes with Petri nets. Component models are first developed to represent the cellular functional units in metabolic networks, i.e., operons, regulons, modulons and individual reactions. A step-by-step procedure is then presented to construct the hierarchical system models accordingly. The usefulness of the proposed model is demonstrated with a fictitious example. The model validity is shown by comparing simulation predictions with experimental data of four distinct systems in the literature.

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