隨著現代人生活型態的改變，美國國家人類活動模式(National Human Activity Pattern Survey)統計現代人待在封閉的建築物中長達87%的時間，因此室內空氣品質逐漸受到重視，越來越多研究證實室內空氣品質與人體健康相關。室內空氣污染物可分為化學性、物理性、生物性，而生物性污染產生多種健康危害，並導致病態建築症候群(Sick Building Syndrome)，且臺灣屬於高濕度地區，若加上通風設備不良，易成為生物性污染物之溫床。
在生物性污染中，國內外圖書館常見真菌生長於書籍上，因紙張特性、空調使用行為、通風不良易導致真菌污染，物品保存不易。此外在空間配置上多為開放式書庫設計，且書庫與座位區交錯，使人體健康易受真菌危害，故須兼顧使用者健康與物品之保存。而過往針對國內圖書館真菌污染現況與使用者健康的調查較少，也少有針對個案之較完善的改善策略。因此本研究目的為實地調查圖書館真菌污染現況，以問卷調查使用者健康狀況與環境感受，最後提出建築改善策略，並評估改善之成效。
經由圖書館生物性污染現況調查後發現，多處書籍受真菌污染，故以問卷探討使用者健康是否受影響，確立提出改善策略之必要與改善對象。真菌偏好高濕度環境，但實際量測後，圖書相對濕度少高於70%，且以黴菌發芽模型評估後，室內並無真菌發芽風險，但圖書館室內確實有真菌污染之現況，且問卷統計分析結果顯示，使用者有四成以上感受到霉味並有症狀反應，而霉味與症狀之關係皆為顯著相關及正相關。
故本研究以改善建築通風換氣為策略，因通風有助於孢子顆粒在空氣中的移動，使其沉降困難、緩解生長，並加速污染物的移除。運用CFD模擬軟體分析室內氣流與污染物分布，提出策略包含改變污染源、人常駐留區、通風換氣之相對位置，以及改善通風換氣的方式，最後以污染物分布、室內空氣餘命SVE6確立改善策略之成效。整體而言，座位區、工作區、書架區之污染量最高值皆有減少，且整體空間污染物之排除量增加，藉此降低真菌污染對保存品與使用者健康之危害。

With the change of modern people's life style. National Human Activity Pattern Survey indicated that people spent up to 87% of time in their life staying in indoor. Considering that more and more studies have confirmed that indoor air quality was related to human health, indoor air quality has been gradually emphasized. Taiwan, located in a subtropical climate zone, with the weather of high humidity which would easily to be a hotbed of biological pollutants when the indoor environment was poorly ventilated.
Because of paper characteristics, air conditioning usage behavior, inadequate ventilation, bookshelf design and layout, library was more likely to become moldy and even resulted that the items were difficult to store and affected human health. So, the objective of this study was to investigate the mold situation of library and proposed improvement strategies for those serious cases.
In this study, 16 libraries in Taiwan, Tainan were carried out the current situation survey, results found that many books are contaminated by fungi in most of libraries. According to tha questionnaires, more than 40% occupant feel musty and had symptomatic reactions, and the results also found that the relationship between musty and symptoms was significant (P < 0.05) in statistical. Then, the mold germination risk was used to evaluate the mold level of libraries. Questionnaire and the mold germination risk model establish the necessity, methods, and objects of improvement strategies. Finally, the CFD was used to simulation the improvement strategies and SVE6 was used to evaluate the ventilation efficiency.
The simulation results showed that the amount of pollution in the seating area, work area and bookcase area has been reduced. Increased discharge of pollutants throughout the indoor space，In addition, the evaluated results of SVE6 (residual life time of air) found that decrease the pollutants discharge time which means the ventilation efficiency was be improved.

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