本研究目的係以噴塗作業勞工呼吸道及皮膚暴露揮發性有機化合物之採樣結果，結合空氣及皮膚之半定量暴露評估模式推估之長期暴露資料庫，利用貝氏決策分析(Bayesian decision analysis, BDA)技術，建立噴塗作業之長期揮發性有機化合物暴露危害評估。本研究包含現場勞工暴露調查與半定量模式選用兩大部分。現場勞工暴露調查選取噴塗作業勞工進行空氣及皮膚採樣，分別利用活性碳採樣管及活性碳貼布進行個人採樣，所獲得樣本以GC-FID進行分析，分析之物質包括：二甲苯、乙苯、正丁醇與異丁醇。分別選用三種空氣之半定量模式(新加坡「SQRA」、荷蘭「Stoffenmanage」及「Advanced Reach Tool (ART)」)及兩種皮膚之半定量模式(荷蘭「DREAM」與荷蘭「Stoffenmanage」)進行四種揮發性有機化合物之評估，將現場調查之暴露參數應用至半定量模式，藉由斯皮爾曼等級相關係數分析半定量模式結果與現場暴露濃度之相關性。
結果顯示空氣之半定量模式中，以ART之相關性最高，其呈現中度以上相關(乙苯：rs=0.713，p＜0.05)，皮膚之半定量模式中，以DREAM之相關性最高，其呈現中度相關(二甲苯：rs=0.486，p<0.05)，將上述半定量模式以線性回歸校正，修訂分別適用於評估噴塗作業空氣及皮膚暴露之半定量模式，作為勞工暴露預測模式。貝氏決策分析中顯示於半開放腔體噴漆之勞工進行作業時，其暴露超出容許範圍之機率較高，需進一步對危害進行控制。

The purpose of this study is to develop the suitable semi-quantitative models for establishing inhalatory and dermal long-term exposure data bank, and to combine them with the field sampling data to assess spraying workers’ long-term volatile organic compounds (VOCs) exposures via the use of Bayesian decision analysis (BDA) technique. In the field study, we collected spraying worker exposures of both inhalatory and dermal VOCs using charcoal tubes and charcoal patches, respectively. All collected samples were analyzed using the GC-FID for analyzing four chemical compounds, including xylene, ethylbenzene, n-butanol and isobutanol. For semi-quantitative models, we investigated the relevant exposure factors during spraying operations and applied them to the three semi-quantitative models of inhalatory exposures (Singapore-SQRA、Holland-Stoffenmanage and Advanced Reach Tool) and two of dermal exposures (Holland-DREAM and Holland-Stoffenmanage). Finally, we analyzed the correlation between models and sampling results by calculating the corresponding Spearman's rank correlation coefficients.
Results show that Advanced Reach Tool and DREAM had the highest correlation for inhalatory exposures (ethylbenzene：rs=0.713，p＜0.05) and dermal exposures (xylene：rs=0.486，p<0.05), respectively. The semi-quantitative models were calibrated by linear regression. The long-term exposures were estimated using Bayesian decision analysis. The results showed that inhalation exposures of all studied chemicals and dermal exposures of xylene posed on semi-opening chamber spraying workers were consistently found to be unacceptable. Hence, the control strategies (e.g., using appropriate respiratory protecting equipments) for semi-opening chamber spraying workers are needed to reduce their exposure levels.

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